HealthDay News – Approximately 1 in 5 girls with type 2 diabetes has polycystic ovary syndrome (PCOS), according to a systematic review and meta-analysis published online in JAMA Network Open.
Milena Cioana, from McMaster University in Hamilton, Ontario, Canada, and colleagues conducted a systematic literature review to determine the prevalence of PCOS in girls with type 2 diabetes and to assess the association of obesity and race with this prevalence.
Based on 6 studies (470 girls with type 2 diabetes), the researchers found that the prevalence of PCOS was 19.58%. When excluding studies that did not report PCOS diagnostic criteria, the calculated prevalence was 24.04%. Results should be considered with caution because of the studies that did not report the criteria used to diagnose PCOS, which is a challenge during adolescence.
“It is critical that active screening for PCOS in girls with type 2 diabetes is initiated at diabetes diagnosis and follows international evidence-based guidelines for diagnosing PCOS in adolescents,” the authors write. “The associations of obesity and race with PCOS prevalence among girls with type 2 diabetes need further evaluation to help define at-risk subgroups and implement early assessment and treatment strategies to improve management of this type 2 diabetes-related comorbidity.”