A recently published report describes the case of a 59-year-old male patient who experienced olmesartan-associated enteropathy (OAE) and highlights the importance of performing thorough medication reviews.
The combination of vancomycin and fecal microbiota transplantation was found to be superior to fidaxomicin or vancomycin in the treatment of patients with recurrent Clostridioides (formerly Clostridium) difficile infection (CDI), according to a study published in Gastroenterology. This randomized, single-center trial was designed to compare the efficacy of fecal microbiota transplantation with that of fidaxomicin…
In overweight and obese women, administering probiotics during the second trimester of pregnancy did not reduce the risk of gestational diabetes mellitus (GDM), according to a study published in Diabetes Care. Researchers conducted the Study of Probiotics In Gestation (SPRING), a prospective,double-blind, randomized controlled trial of probiotics vs placebo, to analyze whether probiotics prevented GDM…
Evaluation of a colorectal cancer (CRC) screening outreach strategy by mailed invitation for either fecal immunochemical test (FIT) or colonoscopy revealed that more primary care patients chose FIT, according to a study published in Preventive Medicine. Researchers conducted post-hoc analyses of data collected from a trial of CRC screening outreach. Patients who were not up-to-date with CRC screening…
Topline data from the Phase 3 STELLAR-4 trial showed that selonsertib, an investigational treatment for patients with compensated cirrhosis due to nonalcoholic steatohepatitis (NASH), was not associated with a significant improvement in fibrosis without worsening of NASH. The safety and efficacy of selonsertib, an oral inhibitor of apoptosis signal-regulating kinase 1 (ASK1), was evaluated in a double-blind,…
Conventional approaches to treatment of opioid-induced constipation include the use of treatment modalities that address non-opioid-related constipation as well as new medications that target the OIC mechanism of action.
Over time, the prevalence of gastroschisis has increased, with more babies born with gastroschisis in areas with high and medium vs low opioid prescription rates.
A greater number of early adverse life events as well as more severe traumatic experiences were found to be associated with an increased risk for developing irritable bowel syndrome.
The number of enteric infection symptom reports was found to decrease with age, although older adults tend to have more severe illness and require hospitalization.
A new clinical guideline from the American Gastroenterological Association focuses on the medical management of patients with mild-to-moderate ulcerative colitis.
