Healthday News — While both improve gastrointestinal symptoms, the low Fermentable Oligo-Di-Mono-saccharides and polyols (FODMAP) diet shows greater benefit for patients with irritable bowel syndrome (IBS) than general dietary advice (GDA), according to a study published online Nov. 20 in the Journal of Gastroenterology and Hepatology.

Mohammad Javad Zahedi, MD, from the Kerman University of Medical Sciences in Iran, and colleagues compared the impact of diets on the clinical response in patients with diarrhea subtype of IBS (IBS-D). Participants were randomized to low FODMAP (55 patients) and GDA (55 patients) for six weeks after a 10-day screening period.

The researchers found that after 6 weeks, the low FODMAP diet significantly improved overall gastrointestinal symptom scores (P < 0.001), stool frequency (P < 0.001), and stool consistency (P = 0.003), compared to the GDA group. At the end of the study period, both intervention groups expressed a significant reduction in overall scores of the IBS-severity scoring system questionnaire, abdominal pain, distension, consistency, and frequency, although this reduction was greater in the low FODMAP diet group.

Continue Reading

“Both low FODMAP diet and GDA in patients with IBS-D led to adequate improvement of gastrointestinal symptoms for 6 weeks,” the authors write. “However, the low FODMAP diet has greater benefits in IBS improvement.”


Zahedi MJ, Behrouz V, and Azimi M. Low FODMAPs diet vs. general dietary advice improves clinical response in patients with diarrhea-predominant irritable bowel syndrome: a randomized controlled trial. Journal of Gastroenterology and Hepatology. 2017 Nov 20. doi: 10.1111/jgh.14051.