Unusual Cause of Chest, Abdominal Pain in Teen Following ACL Repair
A 17-year-old Black adolescent presents with a 1-day history of acute-onset abdominal pain, palpitations, and anemia. Can you make the diagnosis?
Hematology Information Center
Why Are Parents Refusing Vitamin K Administration in Newborns?
Refusal of vitamin K administration is also often correlated with refusal of other preventive care modalities in infants such as hepatitis B vaccination.
Sickle Cell Anemia Update: Gene Therapy Reverses Pain Events for Years
An update on the investigational gene therapy LentiGlobin for sickle cell disease and research on complications and outcomes of this disorder.
Atypical Celiac Disease: Diagnosing Nonintestinal Cases in Primary Care
Atypical celiac disease may present as dermatitis herpetiformis, anemia, elevated transaminases, short stature, and osteopenia/osteoporosis.
Impact of the Opioid Crisis on Pain Treatment in Sickle Cell Disease
Researchers sought to determine what the impact and challenges of the opioid crisis were on pain treatments for patients with sickle cell disease.
Clinical Challenge: Bruising, Bleeding Gums, Nosebleeds in Young College Athlete
A 21-year-old woman presents with complaints of easy bruising, bleeding gums, heavy periods, and nosebleeds. What is her diagnosis?
Major Bleeding Linked to Anticoagulant Overdose in ICU Patients With COVID‑19
Findings from a retrospective chart review showed a need to carefully monitor inflammatory biomarkers and anticoagulant dosage in patients with severe COVID-19.
Model May Predict Postpartum Hemorrhage With Immune Thrombocytopenia
Researchers attempted to develop a predictive model for the risk of postpartum hemorrhage in patients who have ITP.
Quality of Life Improvement Is the Most Important Treatment Goal for Patients With Sickle Cell Disease
Researchers sought to determine what should be the primary treatment goal for patients with sickle cell disease.
CAR-T Cell Therapy Promising in Multiple Myeloma
Researchers sought to determine whether idecabtagene vicleucel, a CAR-T cell therapy, would be a viable treatment option in heavily pretreated patients with relapsed or refractory multiple myeloma.
Mortality Trends in Patients With High-Risk Pulmonary Embolism
Although the mortality of patients with high-risk pulmonary embolism has decreased over time, the decrease cannot be attributed to improved treatments for pulmonary embolism.
Falsely Elevated HbA1c in a Patient With Euglycemia
Certain hemoglobin variants and conditions have been shown to affect red blood cell lifespan and hence may lead to false HbA1c results.
Cognitive Behavioral Therapy Effective Strategy for Chronic Pain Management in Hemophilia
Nonpharmacologic treatment with cognitive-behavioral therapy combined with physiotherapy may be an effective pain management strategy for patients with severe hemophilia.
Transplant Beneficial for Kidney Failure in Sickle Cell
Patients with kidney failure who receive a kidney transplant, including those with sickle cell disease, have lower mortality.
COVID-19 Convalescent Plasma Shows Early Survival Benefit
Researchers assessed the effect of COVID-19 convalescent plasma on survival benefit at 7 and 14 days for patients hospitalized with the disease.
Type O and Rh-Negative Blood Type Protective Against COVID-19
Investigators determined whether ABO and Rh blood groups were associated with risk for SARS-CoV-2 infection and severe COVID-19 illness.
Prophylactic Anticoagulation May Cut COVID-19 Mortality
Prophylactic anticoagulation is associated with reduced risk of 30-day mortality among patients admitted to hospital with COVID-19.
Top January 2021 FDA Approvals
January 2021 FDA approvals of import to physician assistants and nurse practitioners include treatments for HIV, heart failure, dry eye disease, and light chain amyloidosis.
Iron-Deficiency Anemia Secondary to Asymptomatic Celiac Disease: A Case Study
A 21-year-old woman presents with a complaint of continued iron deficiency despite treatment with oral iron supplementation.
Patterns of Bleeding Events in Women and Girls With Hemophilia
A team of investigators evaluated clinical characteristics, hemostasis management, and clinical outcomes of bleeding events in women and girls with hemophilia.
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