Clinical Guidelines Developed for Managing Nosebleeds
Ongoing active bleeding should be treated with nasal packing; patients should be educated on packing.
Hematology Information Center
Blood Biomarkers Do Not Hasten Diagnosis of Transient Ischemic Attacks
Currently available blood biomarkers are not ready to replace clinical signs and symptoms in the diagnosis of transient ischemic attack.
Endurance Exercise May Offer Vascular Benefit in Sickle Cell Disease
Increases in capillary density, functional exchange surface seen in microvasculature of skeletal muscle.
In T2DM Patients, Anemia Tied to Diabetic Retinopathy
In patients with type 2 diabetes mellitus, anemia is associated with the development of diabetic retinopathy.
Anemia in Early Pregnancy May Harm Child Neurodevelopment
Odds for ASD, ADHD, intellectual disability increased with anemia diagnosed during first 30 weeks.
1,125,000 Men/Boys Expected to Have Hemophilia Worldwide
Prevalence of all severities of hemophilia A and hemophilia B estimated at 17.1 and 3.8 cases per 100,000.
Novel Therapy Treats Triple-Class Refractory Multiple Myeloma
Partial response or better observed in 26% of patients receiving oral selinexor-dexamethasone.
Medicare to Cover CAR-T Therapy for Leukemia, Lymphoma
Chimeric antigen receptor T-cell therapy boosts a patient’s own immune cells.
Depression at Time of Diagnosis May Worsen Survival in Blood Cancers
Risk for death higher even with depression remission vs never experiencing depression.
WHO Updates List of Essential Medicines
The World Health Organization (WHO) has updated the WHO Model List of Essential Medicines for 2019.
Factors Associated With Long-Term Fatigue in Non-Hodgkin Lymphoma Survivors
Severe fatigue was more common in NHL survivors compared with the general population.
Voxelotor Improves Hemoglobin Levels in Sickle Cell Disease
Fewer individuals in voxelotor group versus placebo group have worsened anemia at week 24.
Mortality Not Higher With Transfusions From Female Donors
Findings seen for red blood cells from female, previously pregnant, or sex-discordant donors.
Number of Hematologic Complications of Immune Checkpoint Inhibitors Appears to Be Increasing
Hemolytic anemia and immune thrombocytopenic purpura were the most common complications of immune checkpoint inhibitor therapy.
Body Mass Index Associated With Increased von Willebrand Factor, Factor VIII Levels
For both type 1 and type 2 von Willebrand disease, higher BMI was associated with increased VWF:Ag and FVIII:C levels.
Low Response Rates to Hypomethylating Agents in Chronic Myelomonocytic Leukemia
Researchers evaluated response rates to azacitidine and decitabine in patients with chronic myelomonocytic leukemia according to various sets of response criteria.
FDA: Arizona Company Promoting Unapproved Stem Cell Products for Lyme Disease, Diabetes, Other Serious Conditions
The FDA has sent an untitled letter to R3 Stem Cell, LLC of Scottsdale, Arizona for marketing unapproved stem cell products to treat a variety of diseases and conditions.
Differing Coping Strategies of Patients With Hemophilia
Researchers sought to determine whether disposition and disease severity affected behavioral and cognitive coping strategies in patients with hemophilia.
Managing Pediatric Systemic Lupus Erythematosus in Thrombotic Thrombocytopenic Purpura
Researchers recommended performing lactate dehydrogenase level and blood smear testing in patients with renal and neurological symptoms.
Cerebrovascular Disease: A Serious Complication After Allogeneic Hematopoietic Stem Cell Transplantation
Patients who developed cerebrovascular disease following allogeneic hematopoietic stem cell transplantation experienced decreased survival.
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