Clinical Challenge: Bruising, Bleeding Gums, Nosebleeds in Young College Athlete
A 21-year-old woman presents with complaints of easy bruising, bleeding gums, heavy periods, and nosebleeds. What is her diagnosis?
Hematology Information Center
Major Bleeding Linked to Anticoagulant Overdose in ICU Patients With COVID‑19
Findings from a retrospective chart review showed a need to carefully monitor inflammatory biomarkers and anticoagulant dosage in patients with severe COVID-19.
Model May Predict Postpartum Hemorrhage With Immune Thrombocytopenia
Researchers attempted to develop a predictive model for the risk of postpartum hemorrhage in patients who have ITP.
Quality of Life Improvement Is the Most Important Treatment Goal for Patients With Sickle Cell Disease
Researchers sought to determine what should be the primary treatment goal for patients with sickle cell disease.
CAR-T Cell Therapy Promising in Multiple Myeloma
Researchers sought to determine whether idecabtagene vicleucel, a CAR-T cell therapy, would be a viable treatment option in heavily pretreated patients with relapsed or refractory multiple myeloma.
Falsely Elevated HbA1c in a Patient With Euglycemia
Certain hemoglobin variants and conditions have been shown to affect red blood cell lifespan and hence may lead to false HbA1c results.
Mortality Trends in Patients With High-Risk Pulmonary Embolism
Although the mortality of patients with high-risk pulmonary embolism has decreased over time, the decrease cannot be attributed to improved treatments for pulmonary embolism.
Cognitive Behavioral Therapy Effective Strategy for Chronic Pain Management in Hemophilia
Nonpharmacologic treatment with cognitive-behavioral therapy combined with physiotherapy may be an effective pain management strategy for patients with severe hemophilia.
Transplant Beneficial for Kidney Failure in Sickle Cell
Patients with kidney failure who receive a kidney transplant, including those with sickle cell disease, have lower mortality.
COVID-19 Convalescent Plasma Shows Early Survival Benefit
Researchers assessed the effect of COVID-19 convalescent plasma on survival benefit at 7 and 14 days for patients hospitalized with the disease.
Type O and Rh-Negative Blood Type Protective Against COVID-19
Investigators determined whether ABO and Rh blood groups were associated with risk for SARS-CoV-2 infection and severe COVID-19 illness.
Prophylactic Anticoagulation May Cut COVID-19 Mortality
Prophylactic anticoagulation is associated with reduced risk of 30-day mortality among patients admitted to hospital with COVID-19.
Top January 2021 FDA Approvals
January 2021 FDA approvals of import to physician assistants and nurse practitioners include treatments for HIV, heart failure, dry eye disease, and light chain amyloidosis.
Iron-Deficiency Anemia Secondary to Asymptomatic Celiac Disease: A Case Study
A 21-year-old woman presents with a complaint of continued iron deficiency despite treatment with oral iron supplementation.
Patterns of Bleeding Events in Women and Girls With Hemophilia
A team of investigators evaluated clinical characteristics, hemostasis management, and clinical outcomes of bleeding events in women and girls with hemophilia.
Hematopoietic Stem Cell Transplantation May Not Reduce Renal Function in Sickle Cell Disease
For patients with sickle cell disease, HSCT may not be associated with a significant increase in CKD incidence or prevalence following transplantation.
Iron Deficiency Anemia: Vitamin C Supplementation May Not Be Necessary
For patients with iron deficiency anemia, oral iron supplementation use alone is comparable to oral supplementation with vitamin C.
High-Dose Anticoagulation May Not Aid COVID-19 Patients
Higher doses of blood thinners are potentially harmful and have no clear benefits for hospitalized COVID-19 patients.
ASH 2020 Guidelines on Venous Thromboembolism Management
The American Society of Hematology released evidence-based guidelines for the treatment of DVT and PE in patients without cancer.
Serum Antiphospholipid, Phospholipid-Binding Protein Antibodies in Coronavirus Disease 2019
Prothrombotic autoantibodies, similar to those with antiphospholipid syndrome, appear to be elevated in hospitalized patients with COVID-19.
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