INF Treatment Lowers Risk for Diabetes and Mortality in HIV/HCV Coinfection
Sustained virologic response to the HCV in patients with HCV and HIV coinfection is associated with a lowered risk of diabetes and mortality.
Hepatology Information Center
Higher Intake of Whole Grains May Lower Risk for Liver Cancer
Whole grains and possibly cereal fiber, bran appear linked to lower risk for hepatocellular carcinoma.
Impacts of Hypercholesterolemia and Statin Use in Cirrhosis
A team of investigators sought to identify the independent effects of hyperlipidemia and statin exposure on mortality, hepatic decompensation, and hepatocellular carcinoma in individuals with cirrhosis.
Universal Prenatal Hepatitis C Virus Screening Improves Health Outcomes
Universal healthcare screening at the first clinical encounter of pregnancy was found to be cost-effective and improved health outcomes in women diagnosed with HCV and identification of HCV exposure in neonates.
Topline Data Announced for Selonsertib in Patients With Compensated Cirrhosis Due to NASH
Topline data from the Phase 3 STELLAR-4 trial showed that selonsertib, an investigational treatment for patients with compensated cirrhosis due to nonalcoholic steatohepatitis (NASH), was not associated with a significant improvement in fibrosis without worsening of NASH.
ACIP Updates Recommendations for US Adult Immunization Schedule
The ACIP and CDC have approved and released 2019 recommendations for the adult immunization schedule in the US.
Gender Gap Seen in Accessing Alcohol Treatment With Cirrhosis
Women less likely to be treated than men; treatment visit, medication tied to improved 1-year outcomes.
CDC: Proportion of Increased-Risk Deceased Organ Donors on Rise
Increased-risk donors significantly more likely to have positive HBV, HCV screening results.
Physical Activity Associated With Reduced Risk of Hepatocellular Carcinoma
Physical activity was found to be associated with a reduced risk for hepatocellular carcinoma.
Liver Transplants for Alcohol-Linked Disease Increased From 2002 to 2016
Much of the increase due to decrease in hepatitis C virus infection as indication for transplant.
FDA: Chocolates, Candies May Be Contaminated With Hepatitis A
Worker at Bauer’s Candies facility in Kentucky tested positive for hepatitis A.
USPSTF Affirms Guidance for Hep B Screening at First Prenatal Visit
Evidence convincing that universal prenatal screening reduces perinatal transmission of HBV.
Nurse-Led Program in Primary Care Can Improve Detection of Liver Disease
More incident cases identified in intervention arm with nurse-led primary care-based liver clinics.
Genotype G Linked With Liver Fibrosis in Hepatitis B-HIV Coinfection
Investigators sought to determine the association between liver fibrosis and hepatitis B virus genotype G in patients with comorbid HIV and HBV.
Updated Recommendations, Hepatitis A Vaccine Postexposure Prophylaxis and Travel
The Advisory Committee on Immunization Practices Hepatitis Vaccines Work Group has updated recommendations for hepatitis A vaccination for PEP and PrEP.
New Four-Drug Regimen Effective in Patients With HCV Who Inject Drugs
Those with HCV genotype 1 with recent injection drug use and/or current opioid substitution therapy, paritaprevir/ritonavir, ombitasvir, and dasabuvir with/without ribavirin is effective.
Survival Similar With Donor Hearts From Hepatitis C+ Donors
Second study shows no significant difference in patients’ survival based on donor BMI.
Glecaprevir and Pibrentasvir Improve Extrahepatic Manifestations in Hepatitis C
Patients with chronic HCV undergoing short-term glecaprevir and pibrentasvir treatment show improved cardiovascular and metabolic extrahepatic manifestations.
Targeted HCV Testing Misses High Number of Cases in Prisons
Findings based on birth cohort, risk-based testing vs opt-out testing in prison system.
Novel NASH Treatment Gets FDA’s Fast Track Designation
The Company has completed a first in human study in healthy volunteers; a Phase 2 trial in adults with NASH is due to begin soon in the US.
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