HealthDay News — A considerable proportion of women with HIV have a high probability of viremia above 200 copies/mL, according to a study published online May 17 in JAMA Network Open.
Seble G. Kassaye, MD, from the Georgetown University Medical Center in Washington, DC, and colleagues conducted a prospective study of HIV-positive women with a minimum of 5 follow-up visits from 1994 to 2017. Women were categorized into groups based on their probability of achieving viral load suppression below 200 copies/mL.
The researchers identified three trajectory groups with low, intermediate, and high probability of viremia above 200 copies/mL (28.6, 39.4, and 32.0%, respectively). In these groups, the respective mean cumulative years of viral suppression were 18.7, 12.2, and 5.8 years, respectively. Younger age, African American race, Hispanic race/ethnicity, increased levels of depressive symptoms, drug use, lower CD4+ T-lymphocyte counts, and unstable housing were associated with a high probability of viremia. Overall, 71.2% of women demonstrated viral suppression between 2015 and 2017, including 89.6, 83.4, and 35.2% of those with low, intermediate, and high probability of viremia, respectively.
“So, the rosy picture is that 71% of the women achieved viral suppression, but the granular detail tells us that some women are doing very well, with 89.6% of the women in the low probability of viremia consistently suppressed in the recent years, but others are still struggling to get to viral suppression,” Kassaye said in a statement.
One author disclosed financial ties to the pharmaceutical industry.