FDA Approves Veklury as First Treatment for COVID-19
The FDA approved Veklury (remdesivir; Gilead Sciences) for the treatment of COVID-19 in patients aged ≥12 years (weighing ≥40kg) requiring hospitalization.
Infectious Diseases Information Center
NIH: Study Will Identify Most Promising Therapies for COVID-19
So far, the therapies scheduled to be part of the trial are risankizumab, an interleukin-23 antagonist, and lenzilumab, an anti-human granulocyte macrophage-colony stimulating factor monoclonal antibody.
Survey Reveals Factors Contributing to COVID-19 Vaccine Acceptance
To estimate the association between attribute level and probability of choosing and receiving a vaccine, the study authors calculated the average marginal component effects sizes as well as marginal means.
Lessons Learned From a COVID-19 Outbreak at Boston Hospital
The outbreak prompted the hospital’s infection control team to increase testing capacity, modify policies about social distancing and PPE, and review contact tracing protocol to keep patients and providers safe.
Comparing Clinical Features of Seasonal Influenza and COVID-19 in Children
Researchers conducted a retrospective cohort study to compare characteristics of children with a confirmed diagnosis of COVID-19, seasonal influenza A, and influenza B.
CDC: US COVID-19 Deaths Could Reach 233,000 by End of October
COVID-19 deaths in the United States could reach 233,000 by the end of October, according to the US Centers for Disease Control and Prevention.
Individuals With Blood Group O Have Lower Risk for COVID-19
Compared with patients with blood group O or B, a higher proportion of COVID-19 patients with blood group A or AB required mechanical ventilation and continuous renal replacement therapy.
Case Report Details COVID-19 Reinfection in Immunocompromised Patient
A case report detailed reinfection with SARS-CoV-2 in an immunocompromised patient with Waldenström macroglobulinemia.
FDA Releases Guidance for Instructing Patients in Self-Swabbing for SARS-CoV-2 Testing
Verbal instructions may be supplemented with written or animated information to guide patients through the self-collection process.
Only Two-Thirds of Parents Planning to Get Flu Shots for Their Children
One-third of parents say they will forgo the flu vaccination for their children this year, despite public health recommendations.
Rehabilitation Trends in Patients With COVID-19 Requiring Invasive Ventilation
In patients with COVID-19 admitted to the ICU with a high acuity of illness and a prolonged period of mechanical ventilation, the time to start rehabilitation was often delayed because of the severity of an individual’s condition.
Symptoms of COVID-19 Poor Marker for SARS-CoV-2 Infection
Researchers examined the sensitivity, specificity, positive predictive value and negative predictive value of COVID-19 symptoms as a marker of SARS-CoV-2 infection.
Antibodies Decrease With Time After COVID-19 Symptom Onset
Researchers encourage patients recovering from COVID-19 not to wait too long to donate plasma since antibodies disappear rapidly.
CDC Reports Cases of Multisystem Inflammatory Syndrome in Adults
Adult patients with COVID-19 can develop a hyperinflammatory syndrome, which resembles multisystem inflammatory syndrome in children.
Study Findings Do Not Support Use of Lopinavir-Ritonavir for COVID-19
The RECOVERY trial is the first randomized controlled trial to report on the effects of lopinavir-ritonavir in hospitalized COVID-19 patients.
Severe COVID-19 Infection, Death Risk Higher in Comorbid Interstitial Lung Disease
Patients with interstitial lung disease have an increased risk of severe disease and death associated with COVID-19.
Continued Antihypertensive Medication in COVID-19 Lowers Morbidity and Mortality
Researchers conducted a prospective study to analyze the relationship between continued angiotensin-converting enzyme inhibitor (ACEi) or angiotensin II receptor blocker (ARB) use in the hospital and better clinical outcomes (ICU admission, morbidity, mortality).
ACIP Provides Recommendations on Meningococcal Vaccination
Routine vaccination with a quadrivalent meningococcal conjugate vaccine is recommended for adolescents aged 11 to 12 years.
Rising Costs of HIV Preexposure Prophylaxis May Hinder Benefit and Decrease Access
Researchers conducted a retrospective cohort study to analyze national trends in drug payments and other associated costs of HIV PrEP treatment.
Slowing the Spread of Congenital Syphilis: Guidance for Clinicians
A group of researchers provides guidance for diagnosing and treating syphilis, especially for pregnant women who can spread the infection to the fetus.
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