HealthDay News — The intensive care unit (ICU) mortality from COVID-19 is lower than initially thought, with a combined mortality of 41.6% based on 24 studies, according to a review published online in Anaesthesia.

Richard A. Armstrong, MBBS, from Severn Deanery in Bristol, England, and colleagues conducted a systematic review and meta-analysis to examine ICU mortality among patients with confirmed COVID-19. Data were included from 24 observational studies with 10,150 patients identified from centers across Asia, Europe, and North America.

The researchers found that ICU mortality varied from 0% to 84.6% among studies. Outcome data for all patients were reported in 7 studies. In the remaining studies, there was variation in the proportion of patients discharged from the ICU at the point of reporting from 24.5% to 97.2%. The combined ICU mortality was 41.6% in COVID-19 patients with completed ICU admissions. Mortality was broadly consistent across the globe in a subgroup analysis by continent. The reported mortality rates decreased from greater than 50% to close to 40% as the pandemic progressed.

“There were no significant effects of geographical location, but reported ICU mortality fell over time. Optimistically, countries in the later phase of the pandemic may be coping better with COVID-19,” the authors write. “Our analysis is reassuring in that in-ICU mortality is lower than early reports suggested.”


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