HealthDay News — Middle-aged adults with borderline personality disorder (BPD) seem to have an increased cardiometabolic risk, according to a study published online Oct. 24 in Personality Disorders: Theory, Research, and Treatment.

Taylor A. Barber, from the Philadelphia College of Osteopathic Medicine, and colleagues examined the correlation for BPD traits and contemporaneously assessed depressive mood with instrumented measures of cardiometabolic risk in a sample of 1295 non-Hispanic Caucasian and African-American individuals (30 to 54 years) recruited during 2001 to 2005. Dimensional, multi-informant trait measures were used to assess BPD pathology; depressive symptomatology was self-reported; and multiple indicators of insulin resistance, adiposity, dyslipidemia, and blood pressure were used to index cardiometabolic risk.

The researchers found that both BPD features and depressive symptomatology were both related to the extent of cardiometabolic risk. Only BPD was associated independently with risk indicators when BPD and depression were examined simultaneously.

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“Understanding the relationship between BPD pathology and cardiovascular disease risk has implications for direct clinical application, as well as the potential to enrich theories of the interface between physical and psychological functioning,” the authors write.

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