HealthDay News — Vitamin D supplementation could reduce headache attacks per month and headache days per month among migraine patients, according to a review published in the December issue of The American Journal of Emergency Medicine.

Chen Hu, from the Chongqing Hospital of Traditional Chinese Medicine in China, and colleagues conducted a systematic review of randomized controlled trials exploring the effect of vitamin D for migraine patients. Data were included for 6 randomized controlled trials with 301 patients.

The researchers found that vitamin D supplementation could reduce headache attacks per month, headache days per month, and migraine disability assessment questionnaire scores (mean differences, −2.74, −1.56, and −5.72, respectively) compared with controls, but it had no obvious effect on attack duration or headache severity.

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“Our analysis is based on only 6 randomized controlled trials, and all of them have relatively small patient samples,” the authors write. “We need more randomized controlled trials with large patient [samples] to explore this issue.”

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