Data for this analysis were sourced from the Danish High Risk and Resilience Study. Participants were identified through the Danish Civil Registration System and Danish Psychiatric Central Research Register.
In this study, mental disorders were determined using data from the Danish Psychiatric Central Research Register and general medical conditions from the Danish National Patient Register.
Some patients with schizophrenia may experience residual symptoms when treated with antipsychotics, due in part to their side effects. This analysis aims to examine both short-term improvement and residual symptoms of prescribed medication.
Outpatients with schizophrenia who were seeking treatment for cannabis use disorder were recruited between 2017 and 2020 at the Center for Addiction and Mental Health in Canada.
A panel of 15 experts and stakeholders reviewed findings of a systematic literature search and discussed the impact of the COVID-19 pandemic on mental health care, clinical practice, and management of individuals with schizophrenia and BP-I.
A clinical decisions support system provides personalized treatment recommendations on lowering cardiovascular risk factors in patients with schizophrenia, schizoaffective disorder, and bipolar disorder.
Three-quarters of all psychiatric disorders occur by early adulthood (mid-20s). This fact suggests that bio-psychosocial factors occurring from the fetal period through early adulthood could play a crucial role in risk. This nonsystematic review sought to synthesize key epidemiological evidence of relevant risk factors.
Researchers investigated the influencing factors, prevalence, and cognitive characteristics of depressive symptoms in older patients with chronic schizophrenia.
Researchers are exploring affective lability as a therapeutic target for bipolar disorder, but limited evidence exists on its prevalence and impact among people with schizophrenia and other psychosis spectrum disorders.
With people who have major psychiatric disorders being more likely to have comorbidities which could lead to worse results concerning COVID-19, researchers using a US database assessed the odds of testing positive for COVID-19, as well as mortality from COVID-19.
While extreme phenotype sequencing has brought about the identification of high-impact rare genetic variants for many complex disorders, this has yet to be tested in studies of severe schizophrenia. A total of 112 individuals with severe, extremely treatment resistant schizophrenia were sequenced and the burden of rare, damaging missense and loss-of-function variants between severe, extremely treatment-resistant schizophrenia, typical schizophrenia, and controls across mutation intolerant genes were compared.
In a study, perceptual updating was assessed via a random dot motion perception task. Midway through the test, the motion direction changed. Study participants were then asked to report the direction.
Investigators assessed the relationship between clinical and cognitive features and oddball neural deviations across the schizophrenia-bipolar spectrum.
Smoking increases the metabolism of clonidine through the CYP1A2, which may require the dose to be doubled to have the same plasma concentration as a non-smoker.
