This study aimed to evaluate changes in sleep during the COVID-19 outbreak, and used data-driven approaches to identify distinct profiles of changes in sleep-related behaviors. Demographic, behavioral and psychological factors associated with sleep changes were also investigated.
Cognitive behavioral therapy is the first line treatment for insomnia, but studies have reported potential negative effects. This review aims to understand the extent to which adverse events are monitored for and reported in trial literature.
Patients with fibromyalgia suffer from chronic pain, which limits physical activity and is associated with disturbed sleep. However, the relationship between physical activity, pain, and sleep is unclear.
In order to assess the efficacy and safety of JZP-258, a lower sodium alternative product to sodium oxybate, study authors designed a double-blind, placebo-controlled, randomized withdrawal, multicenter study with an open-label safety extension.