CDC: Fully Vaccinated Can Now Go Maskless With Some Exceptions
Fully vaccinated individuals may resume indoor and outdoor activities without wearing masks or physical distancing, except under certain circumstances.
Web Exclusives
Why Colorectal Cancer May Be Increasing in Young People and How You Can Educate Them
Colorectal cancer rates have been rising in younger people for years, and screenings are now recommended to begin at a younger age. How much and why have rates been increasing, and what preventive steps can you teach these patients to lessen their risk?
Direct-Acting Antiviral Therapy Reduces Extrahepatic Manifestations of HCV
Studies have demonstrated an association between direct-acting antiviral therapy and a reduction in both the incidence and severity of extrahepatic manifestations of HCV.
HBV Infection Not Linked to Liver Injury, Mortality in COVID-19
Patients with current or past HBV infection are not at greater risk for liver injury or mortality during COVID-19 infection.
Predictors of Relapse in Patients With Chronic Hepatitis B Who Discontinue Nucleos(t)ide Analogue Therapy
Researchers analyzed data from patients with chronic hepatitis B to identify predictors of relapse in those who discontinued NAs and determined if existing rules for stopping NA therapy can be improved.
Four Bipolar Experiences and Risks Unique to Adolescents
Adolescent patients with bipolar disorder are at a uniquely vulnerable period in their lives, which presents challenges in treatment. What are some of their experiences and risks that medical professionals should be looking out for and communicating to parents?
AANP Applauds Updated Opioid Use Disorder Guidance
Eligible NPs and PAs can now prescribe buprenorphine for up to 30 patients with OUD.
UMSON Offers Post-Grad Certificate in Substance Use and Addictions Nursing
The online 90-hour clinical practicum is designed for registered and advanced practice registered nurses.
Guselkumab Shows Skin Clearance in Psoriasis, Joint Symptom Improvement in Psoriatic Arthritis
At AAD VMX 2021, researchers presented data on skin clearance rates through 5 years with guselkumab in patients with moderate to severe plaque psoriasis.
Pregnancy Found to Increase Risk of First-Time Symptomatic Kidney Stones
The risk for a first-time symptomatic kidney stone begins to increase in the second trimester and peaks 0 to 3 months after delivery, a study findings suggest.
Defining Molecular Endotypes of Allergy, Asthma in Urban Children
High-risk children living in urban neighborhoods in the United States develop specific phenotypes of respiratory health vs disease, which may link environmental exposures in early life to childhood allergic sensitization and asthma.
Suboptimal Asthma Status May Be Linked to Less Physical Activity in Urban Children
Interventions designed to enhance physical activity in urban children with asthma need to address both the management of asthma and physical activity.
Expanding Roles for Advanced Practice Registered Nurses in Oncology
Roles for advance practice registered nurses are expanding in cancer centers.
Small Intestinal Bacterial Overgrowth Linked to Poor Outcomes in Patients With Heart Failure
Investigators sought to determine the prevalence of small intestinal bacterial overgrowth and establish its prognostic value in patients with heart failure.
5 Lifestyle Changes That May Help Overactive Bladder Symptoms
Patients with overactive bladders may experience stress, embarrassment, and a lowered quality of life. However, there are a number of lifestyle changes they can implement that may lessen their symptoms. Making some small changes can be easier than patients realize. What are some changes patients can make?
Hormone Replacement Therapy in Menopause Linked to Asthma Development
Airway symptoms may develop in menopausal women with no prior history of asthma following the initiation of hormone replacement therapy.
Medication-Assisted Treatment is Cost-Effective for Opioid Use Disorder
The researchers sought to assess the cost-effectiveness of OUD treatments and association of treatments with outcomes in the United States.
Number of Nurse Practitioners Reaches Over 325,000
NPs provide patients with high-quality, comprehensive, patient-centered primary, acute, and specialty health care services in more than 1 billion patient visits each year.
The Role of Nurse Practitioners as Prescribers in Cancer Treatment
Nurse practitioners play an essential role in the chemotherapy plan for patients with cancer.
Dupilumab and Topical Corticosteroids Improve Atopic Dermatitis Symptoms
Nearly half of patients in the dupilumab arms achieved all 3 clinically meaningful endpoints in the phase 3 LIBERTY AD PEDS trial.
Patient-Reported Outcomes Best for Assessing Health Status in HFrEF
Patient-reported outcomes are a more sensitive measure than NYHA functional class for assessing changes in health status in HFrEF.
Guideline-Noncompliant Opioids Prescribed for Many With Diabetic Peripheral Neuropathy
Opioids were prescribed to nearly 43% of patients newly diagnosed with diabetic peripheral neuropathy who were started on pain medications.
Rash Following Medication Change Prompts Evaluation of Excipient Allergy
The patient developed a generalized maculopapular rash approximately 3 hours after receiving warfarin.
Younger Teens Highly Susceptible to Lifetime Substance Abuse
Teens who use alcohol, cannabis, tobacco, or illegal drugs are more likely to develop life-long substance abuse disorder than those who start at a later age.
Does Eating Ultraprocessed Foods Raise the Risk for CV Events?
Regular consumption of ultraprocessed foods is associated with an increased risk for CV events and mortality, independent of other CV risk factors.
New DOAC Users Had Lower Risks for Ischemic Stroke, Major Bleeding vs New Warfarin Users
Study authors assessed the effectiveness and safety of DOACs compared with warfarin in patients with valvular atrial fibrillation.
Serosorting vs Condom Use: HIV Prevention Among Men Who Have Sex With Men
Investigators sought to identify variables that influence condom use likelihood with carrying serostatus partners to learn about HIV prevention strategies.
Spinal Cord Stimulation May Provide Relief in Painful Diabetic Neuropathy
At follow-up, 65.9% of the treatment group and 8.5% of the control cohort exhibited improvements in painful diabetic neuropathy.
Intranasal Ketamine Reduces Pain and Concomitant Drug Use for Refractory Headache
This study assessed the efficacy and safety of intranasal ketamine as an outpatient treatment for refractory headache.
Evekeo ODT Approved for Younger Patients With ADHD
Evekeo ODT, a Schedule II controlled substance, contains a 1:1 racemic mixture of dextroamphetamine sulfate and levoamphetamine sulfate.
Diovan Approved for Younger Patients With Hypertension
The approval was based on data from 3 clinical studies that assessed the antihypertensive effect of valsartan in 290 children 1 to less than 6 years of age.
Similar to HIV, COVID-19 Highlights Racial Inequities in Black Communities
Study authors described racial disparities related to the HIV epidemic and compared key findings with the COVID-19 pandemic.
Bariatric Surgery Reduces Cancer Risk in Patients With Nonalcoholic Fatty Liver Disease and Obesity
Investigators examined the effects of bariatric surgery on cancer risk in patients with NAFLD and severe obesity.
Pertussis Vaccination in Pregnancy Not Linked to Asthma, Infections in Children
Tdap exposure is linked to a reduced risk for upper respiratory, gastrointestinal infections in children up to 6 years of age.
Two New Poliovirus Vaccines Safe and Effective in Children and Infants
These 2 randomized, partly-masked studies aimed to address the emergence and spread of circulating vaccine-derived type 2 polioviruses and vaccine-associated paralytic poliomyelitis from Sabin monovalent OPV2.
Low Potassium Dialysate May Improve Inpatient Survival in End-Stage Kidney Disease
Modifying the potassium concentration used for dialysis may decrease mortality risk among hospitalized patients with end-stage kidney disease and severe hyperkalemia, according to investigators.
WHO Influenza Vaccine Recommendation for 2021-22
The 2020-21 flu season was historically low because of mitigating strategies applied to prevent the spread of COVID-19.
2021 Updated Immunization Schedule for Children
The 2021 updates to the child and adolescent immunization schedule are designed to make immunization easier for parents and health care providers.
Blood Cell Score for Identifying Aggressive Melanoma
The myeloid index score captures the prognostic value of blood myeloid cells and may be used in the management of patients with melanoma.
SGLT2i Use Linked to Reduced Mortality in Comorbid HF, Diabetes
SGLT2i use was linked to reduced mortality and morbidity in a real-world cohort of patients with heart failure and diabetes.
Addressing Racial Disparities in COVID-19 Vaccinations: What Do We Know So Far?
The COVID-19 vaccine has been available to citizens for several months, but there are still racial disparities in who is receiving vaccinations. What do we know about these inequities, and what have some states been doing to try and remedy it?
Dietary Fiber Intake Associated With Reduced Uremic Toxins
Patient characteristics, such as dialysis use and diabetes status, appeared to be influential factors.
Endoscopic Surgery Improved OS for Locally Recurrent Nasopharyngeal Cancer
A team of investigators conducted a randomized controlled trial to assess outcomes following salvage endoscopic surgery vs radiation therapy in patients with resectable, locally recurrent nasopharyngeal cancer.
Hand Grip Strength Linked to Greater Bone Size, Strength in Older Individuals
Researchers determined the association between grip strength and distal radius bone density, size, and strength in both older men and women enrolled in the Framingham Osteoporosis study.
mRNA COVID-19 Vaccine Generates Robust Response in Pregnant, Lactating Women
Researchers evaluated the immunogenicity and reactogenicity of COVID-19 mRNA vaccines in pregnant and lactating women compared with women who were not pregnant and those who were naturally infected with SARS-CoV-2 during pregnancy.
Social Media Asthma Promotions Are Inconsistent With GINA Guidelines
Most Instagram posts incorporating a common, asthma-related hashtag promoted products or services that were not supported by the Global Initiative for Asthma (GINA) recommendations.
Retinal Pathology Present in Nearly 20% of Ebola Survivors
In a secondary analysis of data from the EVICT study, conditions such as chorioretinal scarring, retinal detachment, and other posterior pathology were present in 19.2% of EVD survivors.
Premature Mortality Not Associated With Chronic or Increasing Pain Among Patients With Psoriatic Arthritis
Researchers sought to determine if a higher cumulative pain intensity is associated with premature mortality risk in patients with PsA.
Cardiorenal Disease Burden Increased in Type 1 Diabetes Across Lifespan
Patients with type 1 and type 2 diabetes have a high risk of cardiovascular disease (CVD), but now, a new study shows that type 1 diabetes patients are more susceptible to both cardiovascular and renal disease.
Artesunate for Injection Now Available for Severe Malaria
Artesunate and its metabolite DHA are both active against the blood-stage asexual parasites and gametocytes of Plasmodium species including the chloroquine resistant strains.
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