Researchers at the University of Michigan sought to identify the percentage of older adults who may have experienced isolation or loneliness during the COVID-19 pandemic in their National Poll on Healthy Aging.
Considering the impact quarantine has on resources and individual liberty, it is important to evaluate under what conditions individual quarantine can more effectively control COVID-19 than active monitoring.
Although the Centers for Medicare and Medicaid Services had proposed a rule to allow non-physician providers the ability to provide the same services as physicians, more than 120 medical organizations opposed this ruling, and it ultimately was passed with limitations.
Recommendations for pharmacotherapy with antipsychotics as both acute and maintenance treatment of schizophrenia were made following a systematic literature review of current clinical practice guidelines.
Post-hoc analyses of pooled data from the randomized, double-blind ASPIRE 1 and ASPIRE II studies were conducted to assess the effect of esketamine in adult patients with major depressive disorder and active suicidal ideation.
Depression, a significant cause of disability in the United States, is largely managed by primary care providers; therefore, understanding how these clinicians manage depression is an important step toward identifying opportunities for improvement.
In order to assess the efficacy and safety of JZP-258, a lower sodium alternative product to sodium oxybate, study authors designed a double-blind, placebo-controlled, randomized withdrawal, multicenter study with an open-label safety extension.
Researchers conducted an 8-week, open-label, single-arm study and a subsequent 2-stage, sequential, parallel comparison study to assess the use of pimavanserin among patients with Parkinson disease and major depressive disorder.
Clinical trials were conducted to assess the effect brexanolone and zuranolone, neuroactive steroids that are positive allosteric modulators of the gamma-aminobutyric acid receptor, on depression in postpartum women.
Investigators conducted a randomized clinical trial to assess the safety and efficacy of the investigational stimulant AR19 for the treatment of symptoms of attention-deficit/hyperactivity disorder in adults.
Researchers sought to evaluate the prevalence of pre-existing conditions for adverse events and potential drug-drug interactions related to selected atypical antipsychotics and other non-antidepressant agents among adults with treatment-resistant depression.
Research was conducted to assess the impact of initiation of treatment with second-generation antipsychotics and treatment interruptions on weight gain in patients with schizophrenia and bipolar 1 disorder.