Depression, Suicide Concerns Up Among Teens During Pandemic
Increase seen in percent of teens screening positive for depression, positive suicide risk screening, and recent suicidal thoughts.
Web Exclusives
Bydureon BCise Approved for Adolescents With Type 2 Diabetes
The expanded approval was based on data from a phase 3 study that evaluated exenatide extended-release in 82 patients aged 10 to 17 years with type 2 diabetes.
Nurses Experience Fatigue and Lack of Sleep During 12-Hour Shifts
Fatigue resulting from insufficient sleep can negatively affect cumulative daytime performance and hamper adequate patient care.
40% of Incident Heart Failure Diagnoses Occur in Acute Care
46 percent of those diagnosed in acute care had potential heart failure symptoms in previous six months.
1.5 Million Children Left Orphaned by COVID-19 Pandemic
Pandemics carry secondary impacts beyond morbidity and mortality, including children who are left orphaned.
Extended Bisphosphonate Treatment Does Not Improve Survival in High-Risk Early Breast Cancer
There was no benefit to extending zoledronate treatment beyond 2 years.
Survival Up for Multiple Cancer Types for Teens, Young Adults
Limited or no improvement seen in female breast cancer, cervical cancer, ovarian cancer, and bone and joint sarcomas.
CDC/AAP: Face Masks Essential for In-Person Learning
Mask wearing is important as there are concerns about variants being more easily spread among young children, adolescents, and adults.
Early-Stage Hypertension Linked to Increased Prevalence of Retinal Atherosclerosis
The association between high blood pressure and the prevalence of retinal atherosclerosis was examined.
Respiratory Virus Detections, Antibiotic Prescribing Rates Decreased During COVID-19 Pandemic
The researchers tested their hypothesis that a decrease in respiratory virus incidence would be associated with a reduction in inappropriate ambulatory antibiotic orders.
Cardiovascular Health and Risk Among People With HIV Eligible for Primary Prevention
Researchers used global baseline data to examine cardiovascular disease risk factors among middle-aged people with HIV.
Guidelines Updated for Treatment of Sexually Transmitted Infections
Updated recommendations include alternative regimens for bacterial vaginosis, management of Mycoplasma genitalium
Prior Statin Use Linked to Reduced Risk for Death in COVID-19
Risk for death significantly reduced with prior statin and/or antihypertensive use among those with history of CVD and/or hypertension
Antibiotic Use May Increase the Risk of Early-Onset Colon Cancer
The association was observed with colon cancer but not rectal cancer.
FDA Requests Removal of Pregnancy Contraindication for Statins
The FDA conducted a comprehensive review of all available data associated with the use of statins during pregnancy.
Heart Failure With Mildly Reduced Ejection Fraction: Treatment Options Explored
Despite an increasing emphasis on HFmrEF over the past several years, there is a lack of authoritative guidance surrounding therapeutic approaches for these patients.
AAP Issues Guideline for Managing Young Infants With Fever
Recommendations address evaluation, management of fever in infants aged 8 to 21, 22 to 28, 29 to 60 days; role of parents emphasized.
Continuous Glucose Monitoring vs Blood Glucose Meter Monitoring in Type 2 Diabetes
Researchers studied the effectiveness of continuous glucose monitoring in adults with type 2 diabetes treated with basal insulin without prandial insulin in primary care practices.
Obstructive Sleep Apnea Persisting From Childhood to Adolescence Increases Risk for Hypertension
The researchers examined the links between pediatric obstructive sleep apnea (OSA) and elevated blood pressure and OSA’s orthostatic reactivity in adolescence.
High Rate of COVID-19 Vaccine Hesitancy Among Young Adults in United States
As COVID-19 cases rise globally, adolescents and young adults show hesitancy towards taking the vaccine, putting herd immunity at risk.
Restrictive Eating Disorders Up Among Teens During Pandemic
For first 12 months of pandemic, number of admissions at children’s hospital more than double for same period in previous three years
Methamphetamine-Linked Heart Failure Up in California
Increase of 585 percent seen in methamphetamine-associated cardiomyopathy/heart failure hospitalizations from 2008 to 2018
Top June 2021 FDA Approvals
June 2021 FDA drug approvals include treatments for smallpox, weight loss, candidiasis, and Alzheimer disease.
NAPNAP Updates Position Statement on Childhood Obesity
The purpose of the updated statement stems from NAPNAP’s commitment to encouraging healthy lifestyles to establish a foundation of optimal health.
Severity of Gastric Intestinal Metaplasia Can Be Used to Estimate Gastric Cancer Risk
Investigators assessed the incidence of gastric cancer due to gastric intestinal metaplasia using Operative Link on Gastric Intestinal Metaplasia staging.
Many Patients With AMI Have Disturbed Glucose Metabolism but No History of Diabetes
One of the researchers’ goals was to investigate the association between newly detected disturbances of glucose metabolism and long-term prognosis after AMI.
Self-Reported Symptoms of Depression Increase After Recovery From an Acute COVID-19 Infection
With depressive symptoms rising after an acute COVID-19 infection, study researchers looked at whether these symptoms are a consequence of stress associated with COVID or, do they reflect more specific sequelae associated with the pathophysiology of the illness.
Smoking History May Predict Immune Checkpoint Inhibitor Outcomes in Metastatic Non-Small Cell Lung Cancer
A detailed smoking history may help to inform patient outcomes.
Disparities in Breast Cancer Survival Persist for Black Women
Although nearly all metrics improved for racial-ethnic minorities, recent breast cancer-related mortality in Florida still higher in Black women
Seroclearance of Hepatitis B Surface Antigens by 10 Years Rare After Antiviral Therapies
Investigators estimated the incidence of HBsAg seroclearance in patients with hepatitis B virus infection on long-term therapy with entecavir or tenofovir disoproxil fumarate.
Hepatitis B Virus Monitoring Needed After Liver Transplantation
While the risk is small, there have been 20 cases of unexpected donor-derived hepatitis B virus infection
Critical Care NPs Successfully Identify Patients at High Risk for ICU Readmission
More than one-third of patients deemed at high risk had an unplanned ICU readmission during their hospitalization.
Omega-3 Fatty Acids Tied to Better Cardiovascular Outcomes
Cardiovascular risk reduction more prominent with EPA monotherapy versus EPA + DHA therapy
Digital Self-Monitoring Effective for Weight Loss, Healthy Lifestyle
Finding significantly associated with tailored advice among adults with obesity, overweight
Bariatric Gastric Bypass Surgery Alters Gut Microbiome in Adults With T2D and Mild Obesity
Researchers assessed how gut microbiota changes are associated with anthropometric, metabolic, and inflammatory profiles following metabolic surgery in adults with type 2 diabetes and mild obesity.
Metformin Possibly Beneficial in Advanced Prostate Cancer
In a randomized controlled study, adding metformin to androgen deprivation therapy for low-tumor-volume metastatic hormone-sensitive prostate cancer significantly delayed development of castration-resistant disease.
Study Compares Remote Electrical Neuromodulation to Migraine Meds in Adolescents
Nerivio is a wireless remote electrical neuromodulation device approved for the acute treatment of episodic or chronic migraine in patients 12 years of age and older.
Oral Contraceptives Lower Ovarian Cancer Risk in BRCA Carriers
Findings seen in BRCA1 and BRCA2 mutation carriers; reduction greater with longer duration of use in BRCA1 carriers
CDC Issues Alert About Respiratory Syncytial Virus Spread in Southern US
Agency is encouraging broader testing for RSV among patients presenting with acute respiratory illness who test negative for COVID-19
Glucose-Lowering Therapy Delayed for Newly Diagnosed T2DM Patients
Factors in therapeutic inertia examined in adults newly diagnosed with T2DM receiving primary care in the U.K.
Racial Differences Seen in Inherited Risk of Early-Onset Cancer
Higher familial risks for early-onset cancer seen in Latino, Black patients for solid tumors and in Asian/Pacific Islander patients for hematologic cancers
Gestational Diabetes May Increase Risk for Fetal Hypoxia
Hypoxia-related ZigZag pattern, late decelerations of FHR on intrapartal CTG and increased risk of fetal asphyxia seen in GDM pregnancies
Promises and Pitfalls of Wearable Devices for Atrial Fibrillation Detection Evaluated
Using photoplethysmography (PPG) embedded in a smartwatch or wristband, patients can take an ECG with the tap of a button.
Culturally Tailored Shared Medical Appointments Increase Diabetes Knowledge
Intervention significantly increased Black patients confidence in diabetes self-care abilities and perceived knowledge about diabetes.
ADA: Peds Hospitalization Rates for New-Onset T2D Up During Pandemic
Hospitalization rate for new-onset diabetes in children up from 0.27% in 2019 to 0.62% in 2020.
NP-Led Intervention Reduces 30-Day Hospital Readmission Rates, Health Care Costs
A transitional care model utilizing NPs to conduct telehealth visits within 3 days of hospital discharge led to reduce health care costs and increased 14-day follow-up rates.
Heart Failure Linked to Increased Incidence of Cancer
Increased rates of cancer seen among women and men and for cancer at multiple sites, including lip, oral cavity, pharynx, respiratory organs
Pneumococcal Vaccine Associated With Steep Decline in Antibiotic Use Among Children in Israel
Researchers compared trends in antibiotic prescription rates during the period preceding the pneumococcal conjugate vaccine (PCV), as well as the early and late PCV periods, among Jewish vs Bedouin children.
Stool, Rectal Samples Detect Pathogens in Children With Isolated Vomiting
A team of investigators assessed the presence of enteropathogens in children with isolated vomiting.
Asthma Flares Down Among Black, Hispanic Patients During Pandemic
Greatest decrease seen for those previously working outside of the home and in those without ‘allergic-type’ inflammation
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