Opioid Stewardship Program May Improve Opioid Prescribing After Orthopedic Surgery
A health system-wide opioid stewardship program may have a positive influence on opioid prescribing habits after orthopedic surgery.
Web Exclusives
Essential Steps to Implementing Guidelines for Cognitive Dysfunction in Diabetes
Evidence to date suggests that the risk for all-cause dementia is 40% to 60% higher in patients with type 1 or type 2 diabetes.
We Surveyed HCPs About CBD: Here’s What We Learned
How is CBD affecting clinical practices? We surveyed hundreds of HCPs to find out.
Acute Lipoid Pneumonia in Adults Who Used Marijuana Oils in E-Cigarettes
After recent use of marijuana oils in e-cigarettes, 5 patients in North Carolina were diagnosed with acute exogenous lipoid pneumonia.
Diverse Physical Health Outcomes and HIV Infection
Results from an umbrella review of observational studies showed highly suggestive or suggestive evidence for HIV and the presence of several physical health outcomes.
Effect of Hormone Therapy on Muscle Mass in Postmenopausal Women
Although use of hormone therapy can have some protective effect on muscle mass in postmenopausal women, the benefit is small in the general population.
High Rates of Low-Intensity Aggressive, Suicidal Behavior in Early Psychosis
This is the first study to report an association between obstetric complications, atypical development, and aggressive behavior in first-episode psychosis.
Updated Recommendations for Clinical Management of Rosacea
Updated recommendations include discussing disease burden with patients during consultations, and having complete clearance as the primary treatment objective.
Parent-Child Interactive Therapy Effective for Selective Mutism
Children with selective mutism who participated in parent-child interaction therapy showed significant gains in speaking behaviors; teachers and parents also reported improvements in child anxiety.
Better Insight Predicts Worsening and Suicidality in Schizophrenia
New research suggests a temporal cascade from QoL to suicidality via depression in patients with schizophrenia.
Upcoming Clinical Guidance on Chronic Pain Management With Opioids Plus Cannabinoids
Researchers are developing a consensus report to provide clinical guidance for the management of patients with chronic non cancer pain who are taking both opioids and cannabinoids.
CBT and DBT Reduce Suicide Behaviors Compared With Treatment as Usual
Cognitive behavioral therapy (CBT) and dialectical behavior therapy (DBT) are effective psychological treatments that may be used to reduce suicidal risk among adults.
Depression May Attenuate Physical Activity Gains in Diabetes Prevention Programs
Primary care diabetes prevention programs that promote physical activity become less effective when patients experience depressive symptoms.
Pneumococcal Vaccination Responses Greater in Certain Patients
Serotype-specific IgG responses to the pneumococcal vaccine Pneumovax®23 were greater in patients with subnormal IgG1 than subnormal IgG3.
Guidelines for Inpatient Pain Management May Lead to Safer Opioid Prescribing
An interdisciplinary work group has developed new guidelines for inpatient pain management that was perceived as helpful by clinicians.
Type and Timing of Menopausal Hormone Therapy May Affect Breast Cancer Risk
Use of menopausal hormonal therapy for 5 years around the start of menopause may be associated with increased risk for breast cancer.
USPSTF Issues Recs on Using Breast Cancer Risk-Reducing Meds
The US Preventive Services Task Force has issued final recommendations on the use of medications for primary prevention of breast cancer.
Interventions Focused on High-Risk Behaviors May Reduce HIV Transmission
Focusing on interventions that address high-risk sexual behaviors and injection practices may reduce HIV transmission rates among individuals who are HIV-positive and inject drugs.
Effective Intervention Evidence Lacking in Prevention of Vertical Transmission of HIV
Evidence on intervention effectiveness in improving uptake and retention of mothers and infants in the prevention of mother-to-child transmission care in HIV regimens is lacking.
Abnormal Involuntary Movement Scale Scores May Predict Psychosis Risk
Findings showed associations between abnormal involuntary movements and biological markers such as regional cerebral blood flow and grey matter volume in a psychiatric sample, indicating a pathophysiological involvement of the associated motor cortex.
Readdressing Opioid Dose Tapering and Buprenorphine Indications
Recognizing prescription opioid dependence and expanding the use of buprenorphine could improve the quality of life for patients with chronic pain.
Preterm Infants Often Undervaccinated at 19 and 36 Months
Preterm infants are undervaccinated at 19 and 36 months when compared with infants born at term or postterm.
Mindfulness-Related Analgesia May Be Associated With Increased PNS Activity
Greater high-frequency heart rate variability during mindfulness meditation was found to be associated with reduced pain unpleasantness.
C difficile Colonization in Infants May Trigger Antitoxin Immune Response
Infant nontoxigenic and toxigenic C difficile colonization may be linked to humoral immune responses that can provide protection against C difficile infection later in life.
Altered Administration Rule Has Potential to Harm Immigrants and Families
The Department of Homeland Security has expanded the criteria for determining if an individual is considered a public charge.
HIV Infection Associated With Poor Cancer Outcomes
Elderly patients with HIV who have cancer, and specifically breast and prostate cancer, may have worse outcomes when compared with elderly patients without HIV with cancer.
Analgesic Ceiling Dose of Ibuprofen for Acute Pain in the ED Determined
Ibuprofen doses of 400, 600, and 800 mg were found to provide comparable analgesia in adult patients seen in the emergency department with moderate to severe acute pain.
Bullying During Medical Residency May Cause Depression, Burnout
Researchers evaluated survey results to determine the prevalence and impact of perceived bullying during residency.
Link Between Schizophrenia Liability and Magnified Psychological Stress Sensitivity
Among other findings, investigators unexpectedly found that a protective function of schizophrenia liability contrasts with the effect of positive features.
Fixed-Dose Combination Polypill Effectively Prevents Major CV Events
A fixed-dose combination pill may be an effective component of a preventive strategy to reduce cardiovascular disease.
Evolutionary and Anthropologic Compassion for the Death Mother
Dr Sieff explores research that posits being born to a parent who wishes you dead can contribute to the development of schizophrenia and suggests some ways to heal the trauma.
Midlife Hypertension Tied to Changes in Late-Life Brain Structure
Investigators studied the effects of midlife high or increasing blood pressure on late-life brain structure.
Enterovirus A71 Vaccine Effective in Preventing Non-Severe Hand, Foot, and Mouth Disease
This study shows that full EV-A71 vaccination was effective in preventing EV-A71-associated hand, foot, and mouth disease in children, and partial vaccination may also provide protective effects, especially in older children.
High-Dose Short-Term Corticosteroids May Not Increase AEs in Children
Short-term high-dose inhaled or systemic corticosteroid use does not appear to correlate with increased adverse events across organ systems in children aged ≤6 years.
Physician Assistants Given Autonomy Under New IHS Policy
Updates to the Indian Health Service Manual allow PAs to exercise autonomous medical decision making and assume full clinical responsibility for American Indians and Alaska Native people.
Community Health Nursing Intervention Improves Self-Care and Reduces STI Positivity
Investigators of this study sought to compare the efficacy of a community health nursing intervention vs standard of care to improve self-management of pelvic inflammatory disease.
Preventing Persistent Norovirus Outbreaks: Lessons From a Nebraska Event Center
A comprehensive prevention strategy that attempts to address all possible routes of norovirus transmission and a strict ill employee exclusion policy are key to halting successive norovirus outbreaks.
Clozapine Response and Adverse Events Differ Based on Gender
Investigators found data that showed in women taking clozapine the risk of developing diabetes was high, among other risks, and that in men there were cardiovascular risks, including a poorer lipid profile.
Clearance Granted to New HbA1c Test Device
The FDA has granted 510(k) market clearance to the OneDraw A1C Test system, which monitors HbA1c levels in individuals with diabetes for long-term glucose control.
Analyzing Hospital Utilization Following the 1966, 2014 Health Insurance Coverage Expansions
Researchers sought to determine whether the implementation of Medicare and Medicaid in 1966 and the Patient Protection and Affordable Care Act of 2014 affected hospital use.
Sleep Disturbances Associated With Severity of Attenuated Psychotic Symptoms
Investigators found data that showed sleep disturbances correlate with the severity of symptoms in patients with psychosis.
Deficits in P300 Amplitude Associated With Psychosis Risk Syndrome
Researchers found that in patients with schizophrenia P3b might be a biomarker for clinical outcomes in psychosis risk syndrome.
Effects of Total Cumulative and Early vs Late Dose Reductions in FEC-D for Early Stage Breast Cancer
In this retrospective study, researchers sought to determine the survival impact of reductions in total cumulative dose and early vs late dose reductions of third-generation adjuvant chemotherapy regimens in patients with early-stage breast cancer.
FDA Rejects sNDA for Hetlioz in Jet Lag Disorder
The FDA has rejected the supplemental New Drug Application for Hetlioz (tasimelteon; Vanda Pharmaceuticals) for the treatment of jet lag disorder.
Out-of-Network Billing Common for Privately Insured Patients Receiving In-Network Care
Little is known about the frequency and financial repercussions of out-of-network billing, despite frequent news in the media about surprise medical bills.
Targeting Psychosis, Depression, Cognition May Improve Functional Outcomes in Bipolar Disorder
Variables that significantly contributed to functional outcomes in bipolar disorder included a history of psychotic symptoms followed by depression and executive functioning and verbal memory.
HCV, HIV Association With Peripheral Artery Disease Examined
Investigators analyzed the relationship between HIV, hepatitis C virus, and peripheral artery disease in women.
Younger Patients With Colorectal Cancer Experience Delays in Primary Care Referrals
Researchers sought to identify missed opportunities for diagnosis of colorectal cancer in primary care that lead to referral delays and emergency diagnoses in younger patients.
Baseline Urinary Dysfunction May Increase Following Rectal Cancer Treatment
Study concludes that few of the associated risk factors are modifiable and that clinicians should stress possible outcomes related to urinary dysfunction prior to patients receiving treatment for rectal cancer.
Antipsychotics Cause Short-Term Somatic Serious Adverse Events
Researchers found data that showed in older patients with schizophrenia that concurrently somatic serious adverse events occurred independent of treatment and due to treatment with antipsychotics.
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