Are Boiled Peanuts the Answer to Peanut Allergy?
Researchers used sequential doses of boiled peanuts followed by roasted peanuts to desensitize children to peanut allergy.
Web Exclusives
Top January 2023 FDA Approvals
January FDA approvals include treatments for mood disorders, pertussis in infants, Alzheimer disease, and type 2 diabetes.
Odactra Approved for Adolescents With House Dust Mite Allergic Rhinitis
Odactra is an allergen extract indicated as immunotherapy for the treatment of HDM-induced allergic rhinitis.
FDA Greenlights Ibuprofen Oral Suspension Compounding to Help With Hospital Supply
Increased demand for ibuprofen oral suspension products due to a surge in 3 circulating viruses prompted the Agency to issue compounding guidance.
Emzahh Gets FDA Approval for Pregnancy Prevention
Emzahh is an AB-rated generic equivalent of Ortho Micronor.
Liver May Be Reservoir for HIV DNA in Patients With HBV Coinfection on ART
Researchers evaluated whether HIV DNA persists in the liver among individuals receiving suppressive antiretroviral therapy.
Brodalumab Promising for the Treatment of Plaque Psoriasis in a Real-World Setting
The effectiveness and safety profile of brodalumab during a period of 104 weeks in everyday practice are reported.
Acetaminophen Cuts Risk of Acute Kidney Injury After Cardiac Surgery
Results were consistent for patients with and without pre-existing chronic kidney disease.
Nirsevimab Under Review for Protection Against RSV for All Infants
Nirsevimab is a long-acting anti-RSV for nirsevimab for the prevention of RSV lower.
Adolescent Transition Package Improves Readiness for Independent HIV Care
The tools used in an adolescent transition program to aide patients with HIV infection transition to independent care were evaluated for effectiveness.
Rykindo Approved for Schizophrenia, Bipolar Disorder
The approval was based on data from adequate and well-controlled studies with risperidone long-acting injection (intramuscular).
Systemic Agent Initiation for Psoriasis Is Highest in Spring
Does systemic agent prescribing for psoriasis vary by season or other exacerbating factors?
Safety Signal in Seniors Prompts Investigation of Bivalent COVID-19 Vaccine
The preliminary safety signal was identified by the CDC’s Vaccine Safety Datalink.
Socioeconomic Disadvantages Explain Maternal Age and ADHD Causal Association
Researchers examined the relationship between maternal age and childhood ADHD to determine which factors may mediate or confound the association.
Rybelsus Now First-Line Option for Type 2 Diabetes Following Label Update
Rybelsus is a glucagon-like peptide receptor agonist indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
AAD Releases Updated Guidance on Managing Atopic Dermatitis With Topical Therapies
The guidelines were developed by a multidisciplinary workgroup.
HIV Serostatus Affects Hepatitis C Virus Care Cascade
Researchers sought to evaluate differences in immunologic markers between those with HIV and those at risk for HIV with opioid use disorder.
Semaglutide Plus Lifestyle Intervention Beneficial in Adolescents With Obesity
Investigators sought to evaluate the effect of subcutaneous semaglutide therapy for treatment of obesity in adolescents.
Short- and Long-Term Outcomes Following Laparoscopic vs Open Resection for ICC
Researchers analyzed the outcomes of laparoscopic liver resection of intrahepatic cholangiocarcinoma.
Women With ADHD at Increased Risk for Depression With Hormonal Contraceptive Use
Do women or girls with ADHD using hormonal contraceptives (HCs) have an increased risk for depression compared with HC users who do not have ADHD?
COVID-19 Update: Long COVID Rehab, Post-mRNA Vaccine Myocarditis, and Home Test-to-Treat Program
Recent COVID-19 updates include a successful pacing program for people with long COVID symptoms, a blood marker for post-vaccine myocarditis, and the first home test-to-treat program.
Top December 2022 FDA Approvals
December FDA approvals include treatments for weight loss in adolescents, major depressive disorder, lung cancer detection, metastatic non-small cell lung cancer, multiple sclerosis, and lymphoma.
FDA Allows Certified Retail Pharmacies to Dispense Mifepristone
Mifepristone is a progestin antagonist indicated, in a regimen with misoprostol, for the medical termination of intrauterine pregnancy through 70 days gestation.
ASRA Recommends Screening for Cannabis Use Before Surgery
Frequent cannabis users may have poor response to pain control after surgery and may require more rescue medications such as opioids.
ACP Recommends Bisphosphonates for Initial Treatment of Osteoporosis
The American College of Physicians updated its 2017 guideline on pharmacologic treatment of osteoporosis or low bone mass to prevent fractures in adults.
Best Diets According to the Experts: 2023 Rankings Revealed
A 33 person panel of physicians, registered dietitian nutritionists, and nutritional epidemiologists assessed 24 diets to come up with the final results.
Wegovy Gains Approval for Treating Obesity in Adolescents
Wegovy contains semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist.
Hypertension but Not Medication Type Affects Risk for Severe COVID-19
Researchers sought to assess whether individuals with hypertension have a higher risk for severe COVID-19 compared with those without hypertension and whether systolic blood pressure or the type of antihypertensive medication affects that risk.
Anxiety and Depression Association in Patients With Pediatric Psoriasis
Investigators sought to elucidate the prevalence of anxiety and depression in patients with pediatric psoriasis and advocate for psychological screening and intervention as needed.
Infection-Unrelated Cancers Predominant Among Older Adults With HIV
Researchers evaluated rates of infection-related and infection-unrelated cancers among younger and older adults with HIV infection.
Morning Benzoyl Peroxide, Evening Retinol Regimen May Bring Acne Relief
Investigators assess the efficacy of a morning topical low-dose benzoyl peroxide (BPO) acne treatment combined with an evening retinol treatment in patients with acne.
Do Patients With IBD Continue Using Pain Medication After Starting Advanced Therapy?
Researchers examined pain medication usage trends before and after initiating advanced therapy in patients newly diagnosed with inflammatory bowel disease.
Left Atrial Reservoir Strain Plus CHA₂DS₂-VASc Ups Stroke Prediction
Addition of left atrial reservoir strain also yields predicted net benefit in people without prior atrial fibrillation or stroke
Not All Children With Type 2 Diabetes Have Obesity
Meta-analysis results show the prevalence of obesity among children with type 2 diabetes.
Legislative Update: VA Employee Fairness Act Passed and More PA, NP News
Updates on the VA Employee Fairness Act, AMA’s House of Delegates meeting, and PA Licensure Compact Model Legislation
CDC Extends Growth Charts to Monitor Severe Obesity in Children, Adolescents
Extended method uses additional data from 1999 to 2016 NHANES, rather than extrapolation; improves characterization of extremely high BMI in children
CDC Issues Interim Guidance for Prioritizing Oseltamivir in Influenza Treatment
The issue appears to be related to the availability of generic oseltamivir.
Deaths Mentioning Long COVID Identified in United States
The percentage of COVID-19 deaths with long COVID peaked in June 2021 and April 2022 at 1.2% and 3.8%
2023 Standards of Care in Diabetes Released
ADA’s Dr Gabbay discusses the top changes to the Standards of Care in Diabetes—2023
How Does Physical Exercise Affect Rheumatic Disease Outcomes?
Though patients with rheumatic diseases may think physical activity may exacerbate their pain and fatigue, studies show that exercise can be beneficial to disease activity. How does exercise impact certain rheumatic conditions?
ADHD Medications Not Linked to Cardiovascular Disease Risk
Meta-analysis shows no significant associations between ADHD medication use and cardiovascular disease risk for children, adolescents, or adults or for female patients.
Moderna, Merck Report on Promising Melanoma Vaccine
Companies announced that the vaccine performed well in a small study of patients who had melanomasurgically removed
SGLT2 Use Before COVID-19 May Reduce Adverse Outcomes in Patients With Diabetes
SGLT2 inhibitors are associated with lowest probability for adverse outcomes followed by GPL1 receptor agonists and metformin
HIV Treatment, Prevention Recommendations Updated
Because people with HIV are living longer, management of comorbidities throughout the life span is increasingly important.
Bivalent COVID-19 Vaccines Authorized for Children 6 Months and Older
The bivalent formulations contain the original strain of the SARS-CoV-2 virus and a strain from the BA.4 and BA.5 lineages of the Omicron variant.
New Guideline on Diabetes-Related Hypoglycemia Management Released
Endocrine Society Clinical Practice Guideline examines better ways to manage hypoglycemia in people with diabetes.
Healthier Diets Cut ASCVD Risk by 10% in 8 Weeks
The researchers found that DASH and F/V diets changed 10-year ASCVD risk by −10.3% −9.9%, respectively.
Narcan Nasal Spray Gets Priority Review for OTC Treatment of Opioid Overdose
If approved, the OTC nasal spray would deliver 4 mg of naloxone per spray.
AAP Releases “Choosing Wisely” Recommendations for Pediatric Emergency Medicine
The AAP outlines 5 tests and procedures commonly ordered in pediatric emergency medicine that clinicians and patients should question.
Does Obesity Have an Effect on Patients With IBD Receiving Biologic Treatments?
Researchers examined the association between obesity and risk for surgical procedures, hospitalization, and serious infections in patients with IBD treated with biologics.
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