Management of Pediatric Bowel and Bladder Dysfunction in Primary Care
Pediatric patients with suspected bowel and bladder dysfunction may not need specialty intervention if they receive appropriate treatment in primary care.
Web Exclusives
Integrating Opioid Use Disorder Training in Physician Assistant Education
Following integration of a robust OUD training curriculum, PA students demonstrated improved confidence in their ability to evaulate possible OUD in their patients with complaints of chronic pain.
Gender, Race Linked to Increased Stress in PA Students, Graduates
Gender, race, and ethnicity may influence both stress and sense of belonging in physician assistant programs.
Incorporating Autism Spectrum Disorder Training Into PA Education
Results from a survey deployed by the AAPA found that more PA students are willing to receive proper education and training on the signs of autism spectrum disorder.
Prescription Stimulant Misuse Examined Among PA Students
An anonymous survey administered to PA students found that more than 1 in 10 admitted to misusing prescription stimulants.
Expectations for PA Faculty: Will a Doctorate Degree Be Necessary?
Researchers analyzed PA job postings to determine whether advanced faculty positions preferred candidates with doctorate degrees.
Short-Term Medical Marijuana Therapy for Chronic Pain
Short-term marijuana use may be more beneficial than long-term use for patients with chronic pain.
Buprenorphine Initiation in the Emergency Department Beneficial for Opioid Withdrawal
Researchers conducted a literature search to identify whether buprenorphine initiation in the emergency department would reduce mortality rates in patients suspected of opioid withdrawal.
PAs Recommend Lifestyle Changes to Treat Hypertension
A survey found that most PAs are following JNC 8 guidance and recommending lifestyle changes as first-line treatment for their patients with hypertension.
Factors Influencing Smoking Cessation Can Assist in Intervention Strategies
A survey was administered to former adult smokers in order to identify ways to more effectively target smoking cessation in current smokers.
Medication Reconciliation Training Improves Medication List Accuracy
Researchers implemented a medication reconciliation interview to improve accuracy of and adherence to medication reconciliation.
Higher BMI Linked to Overestimation of Caloric Value in Food
A survey was conducted to assess whether BMI influences the ability of an individual to estimate the caloric value of food.
Benzodiazepine Use in Early Pregnancy Linked to Spontaneous Abortion
According to the results of a recently published nested case-control study, exposure to any benzodiazepine in early pregnancy may increase the risk of spontaneous abortion (SA).
First Anticoagulant Approved to Treat Symptomatic VTE in Pediatric Patients
The FDA has approved Fragmin, a low molecular weight heparin, for the treatment of symptomatic venous thromboembolism to reduce the recurrence of VTE in pediatric patients 1 month of age and older.
Inhaled Levodopa Effectively Maintains ON State in Parkinson Disease
Extension study showed that levodopa inhalation powder maintained its efficacy in achieving an ON state in patients with Parkinson disease experiencing OFF periods.
Anxiety, Depression Associated With Levodopa-Responsive Freezing of Gait in Parkinson Disease
Depression and anxiety are associated with levodopa-responsive freezing of gait in patients with Parkinson disease.
Pimavanserin and Quetiapine Comparable for Psychosis in Parkinson Disease
There were no significant differences between pimavanserin and quetiapine in time to discontinuation, mortality, or improvement in psychosis in patients with Parkinson disease and Lewy body dementia.
NDA for Once-Monthly Injectable HIV Treatment Submitted to FDA
The New Drug Application (NDA) for the long-acting injectable formulation of rilpivirine + cabotegravir (Janssen and ViiV Healthcare) for patients with HIV-1 infection has been submitted to the Food and Drug Administration (FDA).
Hospital-Treated Infections Linked to Risk for Adolescent Eating Disorders
Infections that require hospitalization and treatment with anti-infective agents in childhood are associated with an increased risk for eating disorders in adolescent girls.
Hemolysis, Inflammation, and Iron Overload Characterize Congenital Hemolytic Anemias
Researchers assessed the predictive value of various laboratory parameters for iron overload in patients with congenital hemolytic anemias.
Bipolar Disorder in Siblings May Increase Risk for Cardiometabolic Disease
The unaffected siblings of patients with bipolar disorder have increased risks for dyslipidemia and ischemic stroke.
Determining the Appropriate Use of Trackable Pills and Other Nanodrugs
Although trackable and other nanotechnologies represent medical breakthroughs for treatment of many diseases, they could have unintended implications and thus their use must be carefully considered in the individual case.
Q&A: Long-Term Stroke Risk in Women With Prior Hypertensive Disorders of Pregnancy
Researchers investigated the long-term risk for stroke in women with prior history of hypertensive disorders during pregnancy.
Diagnostic Utility of Bleeding Assessment Tool for Identifying Platelet Function Disorders
A bleeding assessment tool yielded higher scores for patients with suspected or confirmed platelet function disorders.
Integrating Nurse Practitioners, Physician Assistants Into Hepatology and Liver Transplant Roles
As the roles of nurse practitioners and physician assistants continue to evolve, efforts are being made to integrate a NP/PA model into the hepatology and liver transplant field.
Abnormal Superficial White Matter Connectivity Linked to Schizophrenia, Bipolar Disorder
Generalized fractional anisotropy reductions in bundles connecting regions involved in mood regulation and motor function were seen in patients with schizophrenia and bipolar disorder.
Novel Treatment for Schizophrenia Gets FDA’s Breakthrough Therapy Designation
The Food and Drug Administration (FDA) has granted Breakthrough Therapy designation to SEP-363856 (Sunovion), an investigational treatment for schizophrenia.
Prevalence of Alcoholic Fatty Liver Disease in the Unites States, 2001-2016
Prevalence of alcoholic fatty liver disease remained relatively unchanged from 2001 to 2016, but alcoholic fatty liver disease with fibrosis stage 2 and 3 or greater increased significantly.
Lower Body Mass Index in Teens Negatively Associated With Acne
Investigators sought to determine a link between body mass index and acne in this study of youths who reported for obligatory military duty between 2002 and 2015.
Risk for Chronic Pain May Be Doubled in Patients With Gout
A diagnosis of incident or new chronic pain may be twice as likely in patients with vs without gout.
CDC to Receive Large Donation of PrEP Medication to Help With HIV Prevention
Truvada is approved in combination with safer sex practices for HIV-1 PrEP to reduce the risk of sexually acquired HIV-1.
Quadrivalent HPV Vaccine Less Effective in Immunocompromised Youth
Antibody titers to the HPV4 vaccine were lower for all HPV serotypes in individuals who were infected with HIV perinatally than those who were exposed to HIV perinatally.
Nurse-Led Telephone Intervention Beneficial for Medication Adherence in Schizophrenia
Patients with schizophrenia who participated in a telephone intervention problem-solving program were found to have higher rates of medication adherence compared with patients who received routine hospital care for schizophrenia.
Varying Amyloid-β Levels Affect Attitudes Toward Physician-Assisted Death
Attitudes about physician-assisted death vary among patients with Alzheimer disease.
Rates of Lung Cancer Screening Discussions Low Between Physicians and Patients
The rate of discussions between physicians and patients regarding lung cancer screenings is very low.
Gene Therapy Cures Infants Born With SCID-X1
Infants with X-linked severe combined immunodeficiency were found to have fully functioning immune systems following treatment with gene therapy.
Best Practices for the Ethical Use of Nanosensors in Employee Surveillance
The authors explain 5 best practices to encourage nano-enabled worker monitoring programs that are acceptable, effective, and ethical.
Are Febrile Seizures Associated With Increased Sudden Death Risk in Young Children?
Recent data suggest that FS may contribute to sudden unexplained death in childhood.
Anemia in Pregnancy Associated With Adverse Maternal, Infant Outcomes
Anemia in pregnancy is associated with obstetric and maternal complications, as well as a higher risk for preterm birth for the infant.
Individualized Management Approach May Improve Care and Cut Costs for Sickle Cell Pain
A multidisciplinary intervention strategy led to a 61% decrease in hospital stay duration for patients with sickle cell disease and vaso-occlusive pain.
Childhood Trauma Associated With Increased Risk for Suicide in Schizophrenia
Investigator data shows a higher risk for suicide in patients with schizophrenia who have experienced childhood trauma with an increase in suicidal ideation linked to neglect and depression, while suicide attempts were associated with sexual abuse.
Apremilast Effective for Patients Dissatisfied With Topical Corticosteroids
Addition of apremilast to a regimen of topical corticosteroids was safe and effective in patients with moderate plaque-type psoriasis.
Repetitive TMS Effective for Comorbid Major Depressive Disorder, Anxiety
In those with comorbid major depressive and anxiety disorders, 23.3% met criteria for remission.
Self-Stigma Correlated With Depression in Individuals With Schizophrenia
Self-stigma significantly affected patients who are afraid to disclose their disease, which results in increased depression.
Treatment-Emergent Adverse Events With Lasmiditan Use for Acute Migraine
Study evaluated safety profile of lasmiditan based on findings from the 2 phase 3 studies (SPARTAN and SAMURAI) for the treatment of acute migraine.
Diazepam Nasal Spray Safe to Treat Frequent Breakthrough Seizures in Epilepsy
Diazepam nasal spray is safe and well tolerated in people with epilepsy who have frequent breakthrough seizures.
Cigarette Smoking Increases MS Severity Despite Smoke Load, Smoking Cessation
Cigarette smoking is associated with more severe multiple sclerosis disease course with lower lifetime cigarette smoking load and smoking cessation having no significant effect on disease severity.
FDA Passes on Barhemsys NDA Again Due to Facility Issues
The FDA has issued a second complete response letter to Acacia Pharma regarding the New Drug Application for Barhemsys (amisulpride injection).
Breastfeeding Rates Lower Among Women With Rheumatoid Arthritis
Participants indicated that the main reason they discontinued breastfeeding was the restart of their medication.
Is Turmeric Good For You? Here’s What Science Says
Is turmeric good for you? We look at what science has to say about its potential role in combating cancer, type 2 diabetes, depression, and arthritis.
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