HealthDay News — Drinking green tea may lessen the effects of the antihypertensive medication nadolol, results of a small, preliminary study suggest.

Shingen Misaka, PhD, from Fukushima Medical University in Japan, and colleagues gave 10 volunteers a single dose of 30 milligrams of nadolol after they had consumed either water or about three cups of green tea daily for 14 days.

Blood levels of the drug were 76% lower in the group that drank green tea compared to the water-drinking group, the researchers reported in Clinical Pharmacology & Therapeutics.

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“Individuals who take nadolol and also consume green tea should be aware of this potential interaction and discuss this with their physician,” Gregg Fonarow, MD, a professor of cardiology at the University of California, Los Angeles, and a spokesman for the American Heart Association, told HealthDay. He reviewed the findings but did not take part in the study.


  1. Misaka S et al. Clin Pharmacol Ther. 2014; doi: 10.1038/clpt.2013.241.