HealthDay News — Higher dietary intake of whole grains may reduce the risk of coronary heart disease, results of a meta-analysis published in The American Journal of Cardiology indicate.

“Epidemiologic studies evaluating the association of whole-grain intake with risk for coronary heart disease (CHD) have produced inconsistent results,” noted Gang Tang, MD, of Third Military Medical University in Chongqing, China, and colleagues.

To summarize the evidence from observed studies regarding the association between whole grain intake and risk for CHD, the investigators culled data from 15 cohort studies and three case-control studies involving 14,237 patients with CHD.

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Analysis of data suggested that the highest amount of whole grain intake, compared with the lowest amount of whole grain intake, was significantly associated with reduced risk for CHD (summary relative risk, 0.787). No between-study heterogeneity was observed. This association was significant in the cohort studies but not in the case-control studies. Inverse associations between whole grain intake and CHD risk were found in the United States and Europe.

“This meta-analysis indicates that higher whole-grain intake has a protective effect against CHD,” concluded the researchers.


  1. Tang G et al. The American Journal of Cardiology. 2015; doi: