HealthDay News — Although rates of many hospital-acquired infections are on the decline, more work is needed to protect patients, according to a CDC report.

On any given day, one in 25 patients in the United States will contract an infection through the course of their hospital stay, noted the agency.

Using national data to track outcomes at more than 14,500 health-care centers across the United States, CDC investigators found a 46% drop in central line-associated bloodstream infections between 2008 and 2013. During that same time, there was a 19% decrease in surgical-site infections among patients who underwent the 10 types of surgery tracked in the report.

Between 2011 and 2013, there was an 8% drop in multidrug-resistant Staphylococcus aureus infections, and a 10% fall in Clostridium difficile infections. Both of these infections have prompted concern because some strains have grown resistant to many antibiotics.

Catheter-associated urinary tract infections rose 6% since 2009, but initial data from 2014 suggests that these infections have also started to decrease, according to the CDC report.

Despite these advances, CDC officials reported that the nation did not meet 2013 goals. “More action is needed at every level of public health and health care to improve patient safety and eliminate infections that commonly threaten hospital patients,” wrote the agency.