HealthDay News — If all patients in the United States had their hypertension under control, 56,000 fewer cardiovascular events would occur each year, and 13,000 fewer patients would die – without increasing health costs, research published in the New England Journal of Medicine suggests.

To project the effect of guideline adherence on patients aged 35 to 74 years, Kirsten Bibbins-Domingo, MD, PhD, of the University of California in San Francisco, and colleagues developed a computer program that simulated drug-treatment and monitoring costs, costs averted for the treatment of cardiovascular disease, and quality-adjusted-life-years (QALYs) gained by treating previously untreated patients.

Full implementation of the new hypertension guidelines would reduce deaths and treatment costs for men and women aged 45 to 74 years with cardiovascular disease, found the investigators. It would also prevent patients with moderate hypertension from developing cardiovascular disease.

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The results of the study suggest it’s not cost-effective to treat women aged 35 to 44 years who don’t have cardiovascular disease for moderate hypertension. The researchers did not look at the cost-effectiveness of treating hypertension in patients aged 75 years and older.

“Controlling hypertension in all patients with cardiovascular disease or stage 2 hypertension could be effective and cost-saving,” concluded the study authors.


  1. Bibbins-Domingo K et al. N Engl J Med. 2015; doi: 10.1056/NEJMsa1406751