Healthday News – Multiparametric magnetic resonance imaging may be an accurate detection method for prostate cancer in patients with clinically low-risk cancer, and particularly for cancers with larger volume and higher Gleason grade, according to researchers.
Using multiparametric MRI (T2 weighted, diffusion weighted, and dynamic contrast material enhanced) to examine 100 patients with clinically determined low-risk prostate cancer, Jin Young Kim, MD and colleagues found high diagnostic performance for the detection of cancer. The images were compared to histopathologic examination.
For cancer volumes greater than or equal to 0.05³ cm (with respect to Gleason grade), multiparametric magnetic resonance imaging had a high diagnostic performance.
The accuracy of multiparametric MRI was significantly higher for cancers with a volume greater than 1 cm³, compared to those with a volume of 0.5 to 1 cm³ (87.7% vs. 82.6%; P=0.02) and for cancers with Gleason grades greater than 7 versus grades greater or equal to 6 (89.2% vs. 80.6%; P=0.01).
“Detection of prostate cancer in patients with clinically low-risk cancer with multiparametric [MRI] is highly accurate, and larger cancer volume and higher Gleason grade are associated with higher detection accuracy,” wrote the authors.