HealthDay News — The odds of episodic migraine (EM) are increased in obese versus normal-weight individuals, according to a study published in Neurology.

B. Lee Peterlin, DO, from Johns Hopkins University in Baltimore, and colleagues analyzed data from 3,862 adults participating in the National Comorbidity Survey Replication, 188  of whom had EM.

The International Classification of Headache Disorders was used as the basis for EM diagnosis. Classification of body mass index included underweight (<18.5 kg/m²), normal (18.5 to 24.9 kg/m²), overweight (25 to 29.9 kg/m²) or obese (≥30 kg/m²). A total of 188 participants had EM.

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The odds of EM were 81% greater in individuals who were obese compared with those of normal weight, with a significant trend of increasing odds of EM with increasing obesity status (from normal weight to overweight to obese).

The odds of EM were significantly greater in obese individuals who were younger than 50 years of age (odds ratio [OR], 1.86); white (OR, 2.06); or female (OR, 1.95), compared to the odds of EM in normal-weight individuals.


  1. Peterlin BL et al. Neurology. 2013; doi: 10.1212/wnl.0B013e3182a824f7.