HealthDay News — Childhood obesity prevention programs are beneficial for low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C), according to a study published in Obesity Reviews.

To examine the effects of childhood obesity prevention programs on blood lipids in high-income countries, Li Cai, of Sun Yat-sen University in China, and colleagues conducted a systematic review and meta-analysis of data obtained from 17 relevant randomized controlled trials, quasi-experimental studies, and natural experiments that implemented diet and/or physical activity interventions in children aged two to 18 years.

In 70% of interventions, there were significant or no effects on adiposity and lipid outcomes: adiposity and lipid outcomes were improved in 15% of interventions, although there were no significant effects on either in 55% of programs.

The pooled intervention effect was −0.97 mg/dL−1 for total cholesterol (P=0.408); −6.06 mg/dL−1 for LDL-C (P=0.018); 1.87 mg/dL−1 for HDL-C (P=0.013); and −1.95 mg/dL−1 for triglycerides (P=0.202).

Childhood obesity prevention programs had a significant desirable effect on LDL-C and HDL-C,” concluded the researchers.

“Assessing lipids outcomes provides additional useful information on obesity prevention program benefits.”


  1. Cai L et al. Obesity Reviews. 2014; doi: 10.1111/obr.12227