HealthDay News — Higher carbohydrate intake, particularly starch, is linked to increased breast cancer recurrence risk, according to a study presented at the annual San Antonio Breast Cancer Symposium, held from Dec. 6 to 10.
“Dietary modifications targeting starch intake warrant further investigation as a preventive measure against breast cancer recurrence,” study researcher Jennifer A. Emond, MS, a public health doctoral student at the University of California in San Diego said in a press release.
Edmond and colleagues investigated the effect of carbohydrate intake on breast cancer recurrence in 2,651 women diagnosed with breast cancer within the previous four years.
Carbohydrate intake data were compared based on recurrence status, after being extracted from multiple 24-hour dietary recalls at study entry and one year. After multivariable adjustment, time to recurrence was modeled on year-one changes in carbohydrate intake. Mean carbohydrate intake was 233 g/day at baseline.
There was a mean increase in carbohydrate intake over the first year for participants who had cancer recurrence, versus a decrease for nonrecurrence participants (2.3 versus −2.7 g/day; P=0.188). Starch intake accounted for 48% of overall carbohydrate intake change, the researchers found.
No difference was noted when comparing baseline starch intake with recurrence status (P = 0.219). The mean year-one change in starch intake was −4.1 and −8.7 g/day, among women who recurred and those who did not, respectively (P=0.015); this change was independent of the study intervention (P=0.326). On adjusted analysis, recurrence risk increased 3% based on a 5-g/day starch increase (HR=1.03; 95% CI: 1.01-1.06), among women with low-grade tumors.