Infectious Disease

Nine Cases of Polio-Like Illness Suspected in Children in Illinois

Nine Cases of Polio-Like Illness Suspected in Children in Illinois

Five possible cases reported in Washington state; 14 confirmed cases reported in Colorado.

Rituximab Linked to HBV Reactivation in Patients With Prior Functional Cure

Rituximab Linked to HBV Reactivation in Patients With Prior Functional Cure

The study authors searched MEDLINE from inception through July 2018 to obtain relevant cohort studies and randomized trials assessing HBVr incidence secondary to pharmaceutical agents.

Sofosbuvir-Based Regimens Safe, Effective for Chronic Hepatitis C in the Community

Sofosbuvir-Based Regimens Safe, Effective for Chronic Hepatitis C in the Community

Investigators examined treatment response of sofosbuvir-based DAA in patients with chronic hepatitis C with compensated liver cirrhosis in a community care setting.

More Than 14 Million Preteens Need to Receive HPV Vaccine

More Than 14 Million Preteens Need to Receive HPV Vaccine

14 million need to receive two doses of vaccine to reach goal of 80% vaccination by 2026.

Relationships Between Prescribing for UTI, <i>E coli</i> Bacteremia, Resistance

Relationships Between Prescribing for UTI, E coli Bacteremia, Resistance

New data suggest an association between general practitioners' prescribing habits for urinary tract infections and UTI-related E coli bacteremia incidence.

Active Choice Intervention Effective in Increasing Influenza Vaccination Rates at Primary Care Practices

Active Choice Intervention Effective in Increasing Influenza Vaccination Rates at Primary Care Practices

Influenza vaccination rates decline as the clinic day progresses.

Monovalent Acellular Pertussis Vaccine Safe and Effective for Neonates With Mothers Unvaccinated for Tdap

Monovalent Acellular Pertussis Vaccine Safe and Effective for Neonates With Mothers Unvaccinated for Tdap

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The monovalent acellular pertussis vaccine may be beneficial to neonates whose mothers did not receive Tdap vaccine during pregnancy.

Switching IV to Oral Antibiotics Noninferior for Some Endocarditis Events

Switching IV to Oral Antibiotics Noninferior for Some Endocarditis Events

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For certain patients with endocarditis on the left side of the heart under stable condition, switching from intravenous (IV) antibiotics to orally administered antibiotics is noninferior to staying on IV treatment.

HIV Infection Diagnoses on the Rise in Young Homosexual Men

HIV Infection Diagnoses on the Rise in Young Homosexual Men

Number of HIV diagnoses in those aged 13 to 29 4x higher than those aged 50 years.

HPV Vaccination Decreases High-Grade Cervical Lesions in Women

HPV Vaccination Decreases High-Grade Cervical Lesions in Women

From 2008 to 2015, both cervical intraepithelial neoplasia grades 2, 3 and adenocarcinoma in situ rates and cervical cancer screening declined in women age 18 to 24 years.

Advocacy Group Calls for Shutdown of Sepsis Clinical Trial

Advocacy Group Calls for Shutdown of Sepsis Clinical Trial

Clovers trial seeks to determine which IV fluids, vasopressors combo works best to curb sepsis.

Corticosteroid Use May Modestly Reduce Mortality Risk in Sepsis

Corticosteroid Use May Modestly Reduce Mortality Risk in Sepsis

The use of corticosteroids in sepsis appears to modestly reduce the risk for death and modestly increase neuromuscular weakness but the evidence is not definitive.

Ground Beef Recalled After <i>E Coli</i> Outbreak

Ground Beef Recalled After E Coli Outbreak

Beef was produced and packaged at Cargill Meat Solutions in Fort Morgan, Colo.

High Population Immunity Aids in Global Elimination of Sabin-2 Poliovirus

High Population Immunity Aids in Global Elimination of Sabin-2 Poliovirus

High population immunity is an indicator of the decline in serotype 2 Sabin vaccine poliovirus after serotype 2 oral poliovirus vaccine withdrawal.

Final CDC Update on <i>Salmonella</i> Linked to Backyard Poultry

Final CDC Update on Salmonella Linked to Backyard Poultry

Live chicks, ducklings obtained from relatives, feed supply stores, websites, and hatcheries.

Extreme Flooding Can Up Exposure to Pathogens

Extreme Flooding Can Up Exposure to Pathogens

Increase in levels of E. coli in bayou water samples compared with historical levels.

AHA: Update on Diagnosis, Treatment for Chagas Cardiomyopathy

AHA: Update on Diagnosis, Treatment for Chagas Cardiomyopathy

Prevalence has increased in US; statement aims to increase recognition, improve care.

130 Now Sickened by Salmonella-Tainted Honey Smacks Cereal

130 Now Sickened by Salmonella-Tainted Honey Smacks Cereal

Thirty-four people have been hospitalized, but no deaths have been reported.

Gaps in Prevention, Management of Tickborne Diseases Identified

Gaps in Prevention, Management of Tickborne Diseases Identified

Diagnostic and surveillance limitations and lack of treatment options, vaccines hamper efforts.

Real-World Efficacy of DAAs in African Americans With Chronic HCV GT-1 Infection

Real-World Efficacy of DAAs in African Americans With Chronic HCV GT-1 Infection

Direct-acting antivirals are safe and effective in African-American patients with chronic HCV.

Toward Integrated Care for Hepatitis C Infection and Addiction

Toward Integrated Care for Hepatitis C Infection and Addiction

There is an opportunity to improve HCV treatment rates for people who inject drugs by integrating DAA therapy into current models of community-based addiction.

Immune Cells' Gene Expression May Predict Flu Susceptibility

Immune Cells' Gene Expression May Predict Flu Susceptibility

Expression of KLRD1 by natural killer cells before infection associated with influenza severity.

CDC: Increase in Rate of STDs for Fourth Consecutive Year in US

CDC: Increase in Rate of STDs for Fourth Consecutive Year in US

Nearly 2.3 million total cases of chlamydia, gonorrhea, syphilis diagnosed in the United States in 2017.

USPSTF Reaffirms Screening for Syphilis in Pregnancy

USPSTF Reaffirms Screening for Syphilis in Pregnancy

Screening results in decrease in incidence of congenital syphilis; no harms identified for penicillin.

China Withholding H7N9 Bird Flu Virus Samples From US

China Withholding H7N9 Bird Flu Virus Samples From US

Specimens of the rapidly evolving virus are needed to develop vaccines and treatments.

FDA Approves Two New Oral Treatments for HIV-1 Infection

FDA Approves Two New Oral Treatments for HIV-1 Infection

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Delstrigo is approved as a complete regimen whereas Pifeltro is to be administered in combination with other antiretrovirals.

FDA: Cases of Rare Gangrene of Genital Area Tied to Diabetes Drug Class

FDA: Cases of Rare Gangrene of Genital Area Tied to Diabetes Drug Class

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The infection developed within several months of the patients starting SGLT2 therapy and the drug was discontinued in most cases. All patients required surgery and there was 1 reported death.

CDC: <i>Salmonella</i> Outbreak in 4 States Linked to Kosher Chicken

CDC: Salmonella Outbreak in 4 States Linked to Kosher Chicken

To date, 8 people have been hospitalized and 1 patient has died.

Serogroup B Meningococcal Vaccine, Disease Knowledge Gaps Apparent in Primary Care

Serogroup B Meningococcal Vaccine, Disease Knowledge Gaps Apparent in Primary Care

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Due to a gap in knowledge regarding serogroup B meningococcal (MenB) disease and vaccination, the majority of clinicians are not discussing MenB vaccines with their adolescent patients during routine visits.

CDC: Updated Influenza Vaccination Recommendations for 2018-2019

CDC: Updated Influenza Vaccination Recommendations for 2018-2019

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In general, routine annual vaccination is recommended for all patients ≥6 months of age who have no contraindications.

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