Infectious Disease News Archive
With vaccination, risks reduced for readmission, outpatient visits, fever, clinical evaluations for infection.
Minimum inhibitory concentration levels of resistance to either clarithromycin or metronidazole may play a role in Helicobacter pylori therapy outcome.
Adults hospitalized for pneumonia who received an influenza vaccination during their stay were less likely to seroconvert if they had diabetes, bacterial detection, baseline seropositive titers for influenza B, or influenza vaccination in the previous season.
Evidence convincing that universal prenatal screening reduces perinatal transmission of HBV.
Risk greatest with higher-dose opioids and opioids with immunosuppressive properties.
Flu-positive patients have higher crude mortality and critical illness vs flu-negative patients.
The quadrivalent LAIV4 is less effective than IIV against influenza A/H1N1pdm09 in all pediatric age groups.
Higher incidence seen for in-hospital mortality, acute respiratory failure, acute kidney injury.
More incident cases identified in intervention arm with nurse-led primary care-based liver clinics.
Patients with voriconazole-resistant invasive aspergillosis have a higher mortality rate compared with patients with voriconazole-susceptible infection.
Zoliflodacin was effective in treating gonococcal urogenital and rectal infections, but less effective in the treatment of pharyngeal gonorrhea.
Highest levels of contamination on practitioner stethoscopes, those in patient rooms.
Investigators sought to determine the association between liver fibrosis and hepatitis B virus genotype G in patients with comorbid HIV and HBV.
Small number of reports include infections, vaginal irritation, localized vaginal injury.
After adjustment for confounders, vaccine linked to lower all-cause, cardiovascular death.
The Advisory Committee on Immunization Practices Hepatitis Vaccines Work Group has updated recommendations for hepatitis A vaccination for PEP and PrEP.
Those with HCV genotype 1 with recent injection drug use and/or current opioid substitution therapy, paritaprevir/ritonavir, ombitasvir, and dasabuvir with/without ribavirin is effective.
Second study shows no significant difference in patients' survival based on donor BMI.
Patients with chronic HCV undergoing short-term glecaprevir and pibrentasvir treatment show improved cardiovascular and metabolic extrahepatic manifestations.
A rise in anorectal lymphogranuloma venereum, caused by Chlamydia trachomatis invasive serovars, observed from 2012-2015 in NYC sexual health clinics.
Findings based on birth cohort, risk-based testing vs opt-out testing in prison system.
Gepotidacin, a novel triazaacenaphthelene bacterial type II topoisomerase inhibitor shows potential in treating resistant Neisseria gonorrhoeae.
The Company has completed a first in human study in healthy volunteers; a Phase 2 trial in adults with NASH is due to begin soon in the US.
So far, 32 people across 11 states have become sick with E. coli after eating romaine lettuce.
The approval was based on data from the KEYNOTE-224 study, a single-arm trial in patients with HCC who had disease progression on or after sorafenib or were intolerant to sorafenib; had measurable disease; and Child-Pugh class A liver impairment.
Adherence to the American Association for the Study of Liver Diseases criteria for evaluation and treatment of chronic HBV infection was found to be poor in all practice settings assessed.
Investigators aimed to determine rates and predictors of cirrhosis and cirrhosis-related complications in patients with chronic hepatitis B infection.
Unlike other antibiotics used to treat gonorrhea, zoliflodacin, a spiropyrimidinetrione antimicrobial agent, works by inhibiting DNA biosynthesis by arresting the cleaved covalent gyrase complex, thereby impeding bacterial growth.
These areas often overlap with regions of prevalent nontuberculous mycobacterial lung disease.
Outbreak in North Kivu province is in its fourth month, and there have been nearly 300 cases.
Influenza Vaccines May Protect Against Lab-Confirmed Influenza-Linked Hospitalization During Pregnancy
For women who are pregnant, influenza vaccines may moderately protect against laboratory-confirmed influenza-associated hospitalization.
Overall, 1.7 and 1.0% of all US adults HCV antibody-positive and HCV RNA-positive.
The introduction of DAAs has caused a significant reduction in the percentage of liver transplant recipients for HCV who are viremic after surgery.
Candidates who accept organ from older donor have lower mortality within and beyond 90 days
The CHEST Expert Cough Panel agreed on cough, dyspnea, pleural pain, sweating, shivers, aches, temperature of ≥38°C, tachypnea, and new and localizing chest examination signs as clinical symptoms as criteria suggestive of pneumonia in outpatient adults.
"This is the first new antiviral flu treatment with a novel mechanism of action approved by the FDA in nearly 20 years," said FDA Commissioner Scott Gottlieb, MD.
Prior-season vaccination is not associated with reduced vaccine effectiveness among children aged 2 to 17 years.
Research results indicated vaccination rates declined as clinic day progressed and that active choice intervention was linked with increased vaccinations.
HIV-exposed infants have high rates of congenital cCMV infection, and in utero HIV infection seems to be a major risk factor for cCMV.
HIV-infected Hispanics have an increased risk for human papillomavirus-related cancers than Hispanics in the general population.
Family-centered pediatric advance care planning is associated with a lower likelihood of symptoms and suffering for adolescents with HIV.
Seven percent of those with indications for PrEP were prescribed PrEP, including 2.1% of women.
Universal 1-time screening for chronic HCV infection is cost-effective compared with no screening or with birth cohort-based screening alone.
The American Association for the Study of Liver Diseases (AASLD) and the Infectious Diseases Society of America (IDSA) released updates guidelines for treating hepatitis C infection.
Similar weight, liver enzyme improvements seen with group- and web-based programs for NAFLD patients.
Larger cities with higher base transmission potentials have more diffuse influenza epidemics.
But drinking 1.5 drinks/day linked to increased mortality after adjustment for multiple confounders.
The study authors searched MEDLINE from inception through July 2018 to obtain relevant cohort studies and randomized trials assessing HBVr incidence secondary to pharmaceutical agents.
One of the goals of the US Department of Health and Human Services National Viral Hepatitis Action Plan is to eliminate mother-to-infant transmission of HCV infection.
Investigators examined treatment response of sofosbuvir-based DAA in patients with chronic hepatitis C with compensated liver cirrhosis in a community care setting.
Wide variations in influenza vaccine coverage have been noted across healthcare personnel based on occupation and worksite.
Analysis of 2 phase 3 clinical trials evaluating the safety/efficacy of glecaprevir/pibrentasvir in people with HCV coinfected with HIV-1 found an overall sustained virologic response of 98% at week 12 of treatment in those with or without cirrhosis.
Active Choice Intervention Effective in Increasing Influenza Vaccination Rates at Primary Care Practices
Influenza vaccination rates decline as the clinic day progresses.
A combination single tablet once-a-day regimen of doravirine/lamivudine/tenofovir disoproxil fumarate demonstrated non-inferiority and no significant adverse events when compared with continuation of established antiretroviral therapy in adults infected with HIV-1.
The first human case of a strain of hepatitis E previously found only in rats was diagnosed in a Hong Kong man who received a liver transplant in May 2017.
Ten to 14 days after being hung, curtains show increased MRSA positivity.
Barriers found among PCPs in surveillance of HCC indicate the need for clinical interventions, including provider education.
2017 to 2018 flu strains hit the very young and elderly especially hard; poor vaccine/strain match-up.
Congenital syphilis up from 362 cases in 2013 to 918 in 2017, with 46.17% increase since 2016.
Number of HIV diagnoses in those aged 13 to 29 4x higher than those aged 50 years.
Beef was produced and packaged at Cargill Meat Solutions in Fort Morgan, Colo.
The PELD score underestimates the actual probability of 90-day pretransplant mortality for children undergoing a primary liver transplant.
Inspection at the VIP Spa in Albuquerque detected practices that might spread HIV or hepatitis B and C.
As infections from drug-resistant microbes continue to rise, the development of new antibiotics has declined since the golden age of antibiotic discovery in the mid-20th century.
Curing HCV infection with direct-acting antiretrovirals is associated with regression of liver fibrosis for most patients.
Live chicks, ducklings obtained from relatives, feed supply stores, websites, and hatcheries.
Bisexual females, 'not sure' males have higher prevalence of many sexual risk behaviors.
The researchers found a significant difference in mean time to direct-acting antiviral agent treatment among participants with public insurance payers compared with private insurance payers.
The neuropsychiatric symptoms associated with HCV infection are likely caused by the body's response to the virus' effects on brain function.
A robust anamnestic response was mounted in most adolescents when challenged with a dose of monovalent HBV vaccine.
All children age 6 months and older, including teens, advised to undergo annual immunization.
There is an opportunity to improve HCV treatment rates for people who inject drugs by integrating DAA therapy into current models of community-based addiction.
Direct-acting antivirals are safe and effective in African-American patients with chronic HCV.
Expression of KLRD1 by natural killer cells before infection associated with influenza severity.
Nearly 2.3 million total cases of chlamydia, gonorrhea, syphilis diagnosed in the United States in 2017.
Decision made 'out of an abundance of caution and concern for the safety of students and employees'.
Specimens of the rapidly evolving virus are needed to develop vaccines and treatments.
Delstrigo is approved as a complete regimen whereas Pifeltro is to be administered in combination with other antiretrovirals.
To date, 8 people have been hospitalized and 1 patient has died.
Compared with uninfected individuals, people with HIV controlled with combination antiretroviral therapy are not at increased risk of developing thyroid dysfunction.
Patient navigation may be considered an effective strategy to enhance engagement and continuation in disease treatment among people with HIV.
In general, routine annual vaccination is recommended for all patients ≥6 months of age who have no contraindications.
Lower odds of having detectable viral load for older adults and those using ISTI-based regimen.
In high-volume centers, patients with liver metastases from colorectal cancer may often be eligible for minimally invasive liver surgery via laparoscopy, thereby reducing potential morbidity risks associated with open surgery.
Lower degree of susceptibility to ibalizumab for 9 of 10 patients with virology failure, rebound.
The International Antiviral Society-USA Panel has updated its recommendations for the management and prevention of HIV infection, to reflect the most current data on new treatment regimens and strategies.
Intervention group had greater reduction in condomless sex acts vs standard of care group.
A systematic literature review, published in Clinical Infectious Diseases, found no evidence supporting a benefit to antibacterial therapy for osteomyelitis in patients with stage IV sacral pressure ulcers.
Close to one-third of sexually active HIV-positive men who have sex with men (MSM) have not received syphilis screening in the past 12 months.
First to be vaccinated will be health workers, contacts of confirmed Ebola patients.
Findings among teens diagnosed with pelvic inflammatory disease in the emergency department.
Asian longhorned tick currently considered a greater threat to livestock than to humans.
All 20 recipients experienced HCV cure, good quality of life, excellent renal function.
Sensitization to Aspergillus fumigatus increased the risk for severe asthma.
Enterococci bacteria surviving exposure for longer periods of time.
Circulating hepatic markers may predict the risk for diabetes in women.
ART recommended for almost all HIV-infected; should be initiated as soon as possible post diagnosis.
Women receiving the inactivated influenza vaccine demonstrated superior antibody response compared with those receiving the live attenuated influenza vaccine.
Investigators added hepatitis C virus and HIV screening tests to standard trauma activation laboratory orders.
Drop in median price of WHO-prequalified generic tenofovir from 208 to 32 from 2004 to 2016