Infectious Diseases

Fidaxomicin Effective for Long-Term Cure of <i>Clostridium difficile</i>

Fidaxomicin Effective for Long-Term Cure of Clostridium difficile

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Fidaxomicin demonstrated the strongest evidence for being the most effective treatment in providing a long-term cure for C difficile infection.

High Rates of <i>Salmonella</i> Contamination Identified in Kratom

High Rates of Salmonella Contamination Identified in Kratom

As of end of May 2018, 199 cases of salmonellosis identified that were linked to kratom consumption.

Chagas Disease in the United States: A Growing Public Health Concern

Chagas Disease in the United States: A Growing Public Health Concern

The United States has the seventh highest prevalence of Chagas infection in the Western hemisphere, with most cases seen among immigrants from Latin America.

Public Health Vaccine Opposition Growing in the United States

Public Health Vaccine Opposition Growing in the United States

Inverse association identified between NME rate and MMR vaccine coverage of kindergarteners.

Otitis Media-Related Ambulatory Visits Declined After Pneumococcal Conjugate Vaccine

Otitis Media-Related Ambulatory Visits Declined After Pneumococcal Conjugate Vaccine

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The administration of PCV7 and PCV13 reduced the number of ambulatory visits for otitis media in pediatric patients.

Universal Purchase Programs in the United States May Not Effectively Increase Vaccination Rates

Universal Purchase Programs in the United States May Not Effectively Increase Vaccination Rates

Using state- and individual-level data from the 1995-2014 National Immunization Survey, the effect of a state's Universal Purchase adoption on vaccination rates was estimated.

Viruses Identified As Most Common Cause of Meningitis in UK Adults

Viruses Identified As Most Common Cause of Meningitis in UK Adults

Estimated annual incidence of viral meningitis is 2.73 per 100,000 UK adults.

CDC Surveillance Information for the 2017-2018 Influenza Season in the United States

CDC Surveillance Information for the 2017-2018 Influenza Season in the United States

The 2017-2018 influenza season in the United States (October 1, 2017-May 19, 2018) was a high-severity season.

National HIV Testing Day Is on June 27

National HIV Testing Day Is on June 27

Annual occasion is a good time for health care providers to encourage testing

CDC Issues Update for Resistant <i>Shigella</i> Infections

CDC Issues Update for Resistant Shigella Infections

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The CDC has identified an increasing number of Shigella isolates that test within the susceptible range for the fluoroquinolone antibiotic ciprofloxacin.

Novel Antibiotic for <i>C Difficile</i> Infection Gets FDA's QIDP Designation

Novel Antibiotic for C Difficile Infection Gets FDA's QIDP Designation

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ACX-362E is a targeted, narrow spectrum oral antibiotic that blocks the DNA replication process through inhibition of polymerase III, which has been shown to be bactericidal.

Florida Teen First Human Case of Another Mosquito-Borne Virus

Florida Teen First Human Case of Another Mosquito-Borne Virus

First documented case of Keystone infection in a human.

WHO Independent High-Level Commission on Noncommunicable Diseases Issues Recommendations

WHO Independent High-Level Commission on Noncommunicable Diseases Issues Recommendations

Although heads of state and governments have pledged to reduce premature mortality from noncommunicable diseases by one-third by 2030, many countries are not on track to achieve this goal.

Lyme Neuroborreliosis: Long-Term Survival and Health Outcomes

Lyme Neuroborreliosis: Long-Term Survival and Health Outcomes

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Lyme neuroborreliosis diagnosis had no substantial effect on long-term survival, health, or educational/social functioning yet may be associated with an increased risk of hematologic and nonmelanoma skin cancers.

CDC Says <i>E Coli</i> Outbreak Tied to Romaine Lettuce Is Over

CDC Says E Coli Outbreak Tied to Romaine Lettuce Is Over

197 cases of illness linked to the E coli outbreak, 5 of which were fatal

CDC: Get Vaccinated for Measles Before Traveling

CDC: Get Vaccinated for Measles Before Traveling

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The CDC recommends 2 doses of the MMR vaccine, which provides 97% protection against measles, prior to international travel.

Robust Immune Responses for Herpes Zoster Subunit Vaccine

Robust Immune Responses for Herpes Zoster Subunit Vaccine

Humoral response seen for 97.8% of HZ/su vaccine recipients vs 2% of placebo

CDC: Recommendations on the Use of Heplisav-B Published

CDC: Recommendations on the Use of Heplisav-B Published

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Benefits of protection with 2 doses administered over 1 month make the vaccine an important option for prevention of HBV.

More Comprehensive HDV Surveillance Needed in High-Risk Individuals

More Comprehensive HDV Surveillance Needed in High-Risk Individuals

Future studies might focus on the use of electronic medical record warning systems or other prompts to improve diagnostic test use in at-risk individuals.

Metabolic Syndrome Common With Chronic Hepatitis B Infection

Metabolic Syndrome Common With Chronic Hepatitis B Infection

Metabolic syndrome also associated with higher alanine aminotransferase levels longitudinally

Hepatitis C Screening Increasing Among Baby Boomers

Hepatitis C Screening Increasing Among Baby Boomers

Screening prevalence 11.5 to 12.8%; similar rate for cohort born from 1966 to 1985

A Zika vaccine could virtually eliminate prenatal infections

Zika virus shown to be of moderate to high efficacy in eliminating prenatal infections.

Effectiveness of Shortened Treatment Regimen for Hepatitis C Assessed

Effectiveness of Shortened Treatment Regimen for Hepatitis C Assessed

In this large, real-world cohort of patients with chronic hepatitis C virus infection, equivalent sustained virologic response rates were found with both 8-week and 12-week treatment.

End-of-Treatment HBsAg Levels May Predict HBV Relapse in Chronic Hepatitis B

End-of-Treatment HBsAg Levels May Predict HBV Relapse in Chronic Hepatitis B

End-of-treatment HBsAg levels may be a clinically useful biomarker to predict HBV relapse in patients with chronic hepatitis B regardless of HBeAg status.

Case Study: Headache, Back Pain, and Fever

Case Study: Headache, Back Pain, and Fever

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A 25-year-old woman presents to the emergency department with a chief complaint of headache, back pain, and fever, while also experiencing some vaginal itching and discharge.

Antibiotic-Resistant Bacteria Found in 221 US Healthcare Facilities in 2017

Antibiotic-Resistant Bacteria Found in 221 US Healthcare Facilities in 2017

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Antibiotic resistance is a nationwide issue that affects every state, so how do we combat it?

Pink Eye: Prevention and Treatment Tips from the CDC

Pink Eye: Prevention and Treatment Tips from the CDC

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Pink eye, also known as conjunctivitis, is an inflammation of the conjunctiva.

Daily dose of PrEP raises coverage, protective drug concentrations

Daily dose of PrEP raises coverage, protective drug concentrations

Recommendations for daily doses of emtricitabine (FTC)/tenofovir disoproxil fumarate (TDF) resulted in protective drug concentrations for men and transgender women.

Maternal TDF not effective in reducing hepatitis B transmission

Maternal TDF not effective in reducing hepatitis B transmission

TDF did not reduce mother-to-child HBV transmission in mothers taking hepatitis B Ig and HBV vaccine.

Drug combination effective for hepatitis C

Drug combination effective for hepatitis C

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Elbasvir and grazoprevir, taken in combination for 12 weeks, successfully treated virologic response in patient with hepatitis C genotype 1b.

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