Influenza Information Center Archive

Healthday Provider-demanded flu testing less likely in elderly patients

Provider-demanded flu testing less likely in elderly patients

Younger adults are more likely to have provider-ordered flu testing than older adults.

Feature The flu pandemic of 1918: 100 years later

The flu pandemic of 1918: 100 years later

In 1918, between 50 and 100 million people are thought to have died from the great influenza pandemic, representing as much as 5% of the world's population.

Healthday Multiple flu vaccinations may prevent death, serious infection

Multiple flu vaccinations may prevent death, serious infection

Intensive care and death were greatly prevented in patients who were annually vaccinated.

News Man flu: man-made or real illness?

Man flu: man-made or real illness?

Men may experience a lower immune response than women, adding insight to the man flu debate.

Healthday Flu vaccine safe for individuals with egg allergy

Flu vaccine safe for individuals with egg allergy

Inactivated and live attenuated flu vaccines can be safely administered to people with egg allergies.

News Healthcare system fires 50 employees for refusing influenza vaccination

Healthcare system fires 50 employees for refusing influenza vaccination

A Minnesota-based hospital chain fires about 50 employees for refusal to receive the influenza vaccine.

News Reduced effectiveness of last season's flu vaccine traced to mutation in chicken eggs

Reduced effectiveness of last season's flu vaccine traced to mutation in chicken eggs

New virus mutations make antibody binding difficult as mismatches in vaccines and viruses emerge.

News No evidence that the influenza vaccine causes VTE

No evidence that the influenza vaccine causes VTE

In the 1 to 10 days after flu vaccine administration, there was no increased risk for VTE.

News Positive mood associated with enhanced responses to influenza vaccination

Positive mood associated with enhanced responses to influenza vaccination

Greater positive mood significantly predicted greater antibody responses to the influenza vaccination.

News 2017-2018 recommendations for pediatric influenza vaccination

2017-2018 recommendations for pediatric influenza vaccination

The guidelines include a strong recommendation for annual seasonal influenza immunization for everyone 6 months and older.

Healthday Influenza vaccination rates drop in children when nasal spray is unavailable

Influenza vaccination rates drop in children when nasal spray is unavailable

Total influenza vaccination rates among children in the 2016 to 2017 influenza season dropped 1.6% from the year before.

Healthday Newer influenza diagnostic tests more accurate than traditional tests

Newer influenza diagnostic tests more accurate than traditional tests

Digital immunoassays and rapid nucleic acid amplification tests have higher sensitivities for detecting influenza than rapid influenza diagnostic tests.

News CDC releases updated influenza vaccine recommendations for 2017-2018

CDC releases updated influenza vaccine recommendations for 2017-2018

The Advisory Committee on Immunization Practices has released the guidelines for the 2017-2018 season.

News Influenza A virus transmitted from swine to humans at agricultural fair

Influenza A virus transmitted from swine to humans at agricultural fair

Researchers found the H3N2 virus in swine at state fairs in Ohio and Michigan, which was transmitted to humans.

News Live attenuated influenza vaccine ineffective in children during 2015-2016 season

Live attenuated influenza vaccine ineffective in children during 2015-2016 season

The live attenuated vaccine was ineffective among children between 2 and 17 years of age during the 2015-2016 season.

Healthday Previous maternal influenza vaccine does not weaken newborn benefit

Previous maternal influenza vaccine does not weaken newborn benefit

Researchers found that in a cohort of pregnant women, receipt of influenza vaccine the previous year predicts higher baseline antibody titers and decreased peak antibody responses against all influenza strains.

News Clinician communication affects parental decision-making with pediatric influenza vaccine

Clinician communication affects parental decision-making with pediatric influenza vaccine

About half of patients accepted influenza vaccination for their child if the clinician used a presumptive vs participatory initiation format.

Blog Post The flu vaccine's influence on public health

The flu vaccine's influence on public health

Improving influenza vaccination rates will require a much greater commitment to preventative public health to change public perception of the importance and efficacy of flu vaccination.

News CDC: 101 influenza deaths in children reported for 2016-17

CDC: 101 influenza deaths in children reported for 2016-17

A total of 101 influenza-related deaths occurred among children throughout the 2016-17 flu season.

Video Study finds flu shots less effective for obese adults

Study finds flu shots less effective for obese adults

Study finds flu shots are less effective for obese adults compared to healthy weight individuals.

News CDC: Influenza vaccine rate low this season

CDC: Influenza vaccine rate low this season

Forty percent of people have reported receiving the flu vaccine thus far, including 37% of children.

Healthday Mortality rate from infectious diseases remains unchanged in the United States

Mortality rate from infectious diseases remains unchanged in the United States

The number of patients dying from infections has remained stable, but some disease threats have changed.

News The flu shot versus flu nasal spray—which is more effective?

The flu shot versus flu nasal spray—which is more effective?

In a study of pediatric patients, vaccine coverage in both LAIV and IIV groups was similar.

News FDA approves generic Tamiflu

FDA approves generic Tamiflu

Oseltamivir phosphate can be used to prevent flu in patients aged 1 year and older.

Feature A clinician and patient mistake

A clinician and patient mistake

It is well-accepted that healthcare practitioners have a duty to their patients, but do patients have a duty as well?

Healthday Nasal flu vaccine not recommended for 2016-2017 flu season

Nasal flu vaccine not recommended for 2016-2017 flu season

The nasal flu vaccine had a protection rate of only 3%.

News Concomitant vaccine administration may increase febrile seizure risk

Concomitant vaccine administration may increase febrile seizure risk

Children who receive the influenza vaccine at the same time as PCV or a DTaP-containing vaccine have an increased risk for febrile seizure.

News Predicting viral mutations may improve flu vaccine efficacy

Predicting viral mutations may improve flu vaccine efficacy

Natural viral mutations ensure that the seasonal flu vaccine must be updated on a yearly basis.

News ACIP recommends minor changes in flu vaccination practices

ACIP recommends minor changes in flu vaccination practices

An ACIP panel recommended adding live-attenuated influenza vaccination as an option for individuals with egg allergy of any severity.

Feature A side effect of the flu vaccine?

A side effect of the flu vaccine?

A clinician questions wonders if there is a connection between cardiac arrhythmia and the flu vaccine.

News CDC reports nearly 60% efficacy for influenza vaccine

CDC reports nearly 60% efficacy for influenza vaccine

The ACIP announced the latest vaccine effectiveness percentages at their February 24th meeting.

News CDC urges rapid antiviral treatment of very ill and high-risk patients suspected of having influenza

CDC urges rapid antiviral treatment of very ill and high-risk patients suspected of having influenza

Cases of both influenza A and influenza B have been reported since October 2015.

Feature Flu vaccine in pregnant women

Flu vaccine in pregnant women

A clinician expresses concerns about potentially misleading flu vaccination information for pregnant women.

Feature A clinician's guide for managing patient perceptions of the flu vaccine

A clinician's guide for managing patient perceptions of the flu vaccine

By presenting research on the safety and efficacy of the flu vaccine, clinicians can successfully promote vaccination to patients in their care.

News Influenza vaccine may reduce all-cause mortality rates in patients with heart failure

Influenza vaccine may reduce all-cause mortality rates in patients with heart failure

Patients with heart failure who receive the influenza vaccine may have a lower risk for all-cause mortality compared with those who do not get the vaccine.

Feature Stat Consult: Influenza 
in children

Stat Consult: Influenza 
in children

Learn how to diagnose and treat influenza in children.

Feature The CDC's statistics on influenza—fact or hype?

The CDC's statistics on influenza—fact or hype?


Clinicians debate the fact or hype present in the CDC's most recently released statistics on influenza death rate.

Opinion The flu shot remains a vital healthcare tool

The flu shot remains a vital healthcare tool

Even if the flu shot "misses," as it did last year, it remains one of the best tools we have to help our patients live healthier lives.

Healthday FDA approves adjuvant flu vaccine for use in the elderly

FDA approves adjuvant flu vaccine for use in the elderly

The FDA has approved Fluad, a trivalent flu vaccine with the adjuvant MF59, for use in patients aged 65 and older.

Feature Stat Consult: Influenza in adults

Stat Consult: Influenza in adults

Learn how to diagnose and treat influenza in adults.

Feature Influenza: How serious is it?

Influenza: How serious is it?

Providers should educate their patients on the prevalence of influenza, its potential complications, and the available prevention options.

Healthday Influenza vaccine can prevent pneumonia hospitalizations

Influenza vaccine can prevent pneumonia hospitalizations

The influenza vaccine may be able to prevent approximately 57% of hospitalizations due to influenza pneumonia.

News Early treatment for flu beneficial for seniors

Early treatment for flu beneficial for seniors

Seniors with the flu should be treated as soon as possible in order to reduce hospital stay length and the need for extended care after discharge.

News Higher influenza vaccination rate 
leads to lower risk for seniors

Higher influenza vaccination rate 
leads to lower risk for seniors

Higher influenza vaccination rates among healthy adults may lower the risk for influenza among older adults, according to a study published online ahead of print September 9 in Clinical Infectious Diseases.

News Egg-free influenza vaccine now available

Egg-free influenza vaccine now available

The makers of the egg-free flu vaccine, Flublok, have announced that it is now available nationwide.

News Flu, pneumococcal vaccines recommended by CDC, NFID

Flu, pneumococcal vaccines recommended by CDC, NFID

Clinicians are advised to lead by example and encourage all patients to get their annual influenza vaccine.

Healthday AAP calls for mandatory flu vaccines for children, health care workers

AAP calls for mandatory flu vaccines for children, health care workers

The American Academy of Pediatrics recommends that flu vaccines should be mandatory for children and health care workers.

Healthday Nursing home residents should receive annual flu vaccine

Nursing home residents should receive annual flu vaccine

A new study provides evidence that yearly influenza vaccination benefited residents of nursing homes.

Healthday Decreased flu vaccine efficacy due to differing strains

Decreased flu vaccine efficacy due to differing strains

The strain of H3N2 used in last year's flu vaccine differed from the circulating strain.

MPR Drug News A more effective flu vaccine?

A more effective flu vaccine?

Flublok Quadrivalent vaccine was 33% more effective in preventing flu than the traditional vaccine.

Curated CDC updates vaccine recommendations, approves 9-valent HPV vaccine

CDC updates vaccine recommendations, approves 9-valent HPV vaccine

The CDC's Advisory Committee on Immunization Practices met to vote on updates to several vaccine recommendations, including for HPV.

Healthday Flu vaccine rates low among nursing home workers

Flu vaccine rates low among nursing home workers

More education is needed to increase influenza vaccination rates among nursing home workers.

Healthday Flu vaccine only 23% effective this season

Flu vaccine only 23% effective this season

Most years, the effectiveness of the flu vaccine ranges from 10% to 60%.

Healthday Flu-related outpatient visits increase this season

Flu-related outpatient visits increase this season

The proportion of outpatient visits for flu-like symptoms rose nearly 4% by the end of December 2014.

Healthday Peramivir earns FDA approval to ease flu symptoms in adults

Peramivir earns FDA approval to ease flu symptoms in adults

Patients given paramivir had flu symptoms ease 21 hours sooner compared with patients left untreated.

Healthday High-dose flu vaccine better for seniors in nursing homes

High-dose flu vaccine better for seniors in nursing homes

Stronger improvement in the immune response was seen in frail senior patients living in nursing homes who received a high-dose flu vaccine.

Healthday Less than 50% of Americans received their flu shot so far this year

Less than 50% of Americans received their flu shot so far this year

CDC officials are urging the public to get the flu vaccine even though it may not be as effective against the mutated H3N2 strain.

Curated Dispelling vaccine myths may not increase vaccine uptake

Dispelling vaccine myths may not increase vaccine uptake

Providing corrective information to patients with high concerns regarding the side effects of the flu vaccine didn't encourage vaccination.

Healthday Prepare for a potentially severe flu season

Prepare for a potentially severe flu season

Even though this year's vaccine does not directly protect against the most widely circulated H3N2 strain this year, CDC still urges clinicians to immunize patients.

News Timing of flu vaccine in HIV patients impacts future incidence

Timing of flu vaccine in HIV patients impacts future incidence

Early season influenza vaccination of patients with HIV may influence the risk of infection later in the season.

News Urge all patients to get flu vaccine

Urge all patients to get flu vaccine

Flu-related complications last year caused more than 100 deaths in children and most of whom were not vaccinated.

Feature Provider/pharmacist collaboration reduces flu visits

Provider/pharmacist collaboration reduces flu visits

A key element of the collaborative practice agreement is communication.

Feature Q&A: Over-the-counter medicine use during flu season

Q&A: Over-the-counter medicine use during flu season


The Clinical Advisor asked infectious-diseases specialist Michael E. Klepser, PharmD, about the role over-the-counter agents play in seasonal influenza.

Curated Novel single-dose flu drug shortens fever

Novel single-dose flu drug shortens fever

The investigational drug peramivir has been shown to reduce the duration of symptoms of the flu, according to researchers.

News Influenza vaccine effective in HIV pregnancy

Influenza vaccine effective in HIV pregnancy

Pregnant women with HIV experienced partial protection from the flu when given the trivalent inactivated influenza vaccine.

News High-dose flu shot better for seniors

High-dose flu shot better for seniors

A high-dose trivalent vaccine demonstrated improved protection for seniors against flu than the standard-dose vaccine.

News Antibiotics Rxs more common than antivirals for flu

Antibiotics Rxs more common than antivirals for flu

Among patients diagnosed with PCR-confirmed influenza, more receive antibiotic prescriptions than antivirals.

News Most flu cases asymptomatic

Most flu cases asymptomatic

Reported cases of influenza represent the "tip of a large clinical and subclinical iceberg," researchers say.

News First human death from H10N8 bird flu reported

First human death from H10N8 bird flu reported

Patient died nine days after illness onset; visited live poultry farm four days before illness.

News CDC: False-negatives common with rapid flu tests

CDC: False-negatives common with rapid flu tests

Healthcare providers should not rely entirely on rapid flu tests when determining if patients have influenza.

News Health officials warn of liquid Tamiflu shortage

Health officials warn of liquid Tamiflu shortage

Shortage should be resolved in week; Tamiflu capsules, flu shots widely available, U.S. officials say

News Pediatric quadrivalent flu vaccine effective

Pediatric quadrivalent flu vaccine effective

A novel inactivated quadrivalent flu vaccine was effective in preventing influenza, reducing attack rate in moderate-to-severe disease.

News FDA approves H5N1 bird flu vaccine

FDA approves H5N1 bird flu vaccine

The vaccine is not intended for commercial distribution, but to supplement the national stockpile of influenza vaccines in the event of a pandemic.

News Novel H6N1 bird flu jumps to humans

Novel H6N1 bird flu jumps to humans

A woman from Taiwan has been infected with novel H6N1 influenza A virus, an avian influenza that's been circulating since 1972.

News Gelatin allergy may induce reaction to flu shot

Gelatin allergy may induce reaction to flu shot

A case report describes a 4-year-old undergoing an adverse reaction within 15 minutes of receiving flu shot.

News CDC: Get 2013-2014 flu shot now

CDC: Get 2013-2014 flu shot now

Although influenza activity has been low through mid-October, health officials expect cases to increase in the coming weeks.

News Flu vaccine lowers risk for cardiac events

Flu vaccine lowers risk for cardiac events

Getting a flu shot was associated with lower risk for cardiac events, with the effect more pronounced in those with more active coronary disease.

News Inactivated flu vaccine OK for egg-allergic patients

Inactivated flu vaccine OK for egg-allergic patients

Patients should have vaccine in primary care or allergist office, depending on allergy severity

News Maternal flu vax protects against prematurity, LBW

Maternal flu vax protects against prematurity, LBW

Vaccinating against influenza during pregnancy reduced the odds of a preterm birth during a widespread influenza activity period.

News Combo approach ups flu vaccination in pregnancy

Combo approach ups flu vaccination in pregnancy

Healthcare providers must both recommend the vaccine and offer to vaccinate.

News AAP issues 2013-2014 flu vaccine recs

AAP issues 2013-2014 flu vaccine recs

Don't wait for quadrivalent vaccines to immunize kids against influenza.

News Person-to-person transmission reported with H7N9

Person-to-person transmission reported with H7N9

Almost genetically identical strains of H7N9 avian influenza were isolated from a man in eastern China and his daughter, both who died of the illness.

News Quadrivalent flu vaccine approved for kids younger than 2 years

Quadrivalent flu vaccine approved for kids younger than 2 years

The FDA has approved Fluzone Quadrivalent to protect adults and children aged 6 months and older during the 2013-2014 influenza season.

News Double-dose oseltamivir no better for severe flu

Double-dose oseltamivir no better for severe flu

Doubling the dose of oseltamivir has no virological or clinical advantage compared with standard-dose treatment for children with severe influenza.

News H7N9 bird flu resistant to oseltamivir

H7N9 bird flu resistant to oseltamivir

A study shows that drug-resistant mutations have been identified in patients infected with the avian H7N9 influenza A virus.

News Vaccine in development as bird flu epidemic spreads

Vaccine in development as bird flu epidemic spreads

Although no evidence exists of sustained ongoing human-to-human H7N9 transmission, health officials are taking steps to prepare for a potential pandemic.

Feature Swine flu crisis stirs vaccine debate

Swine flu crisis stirs vaccine debate

In response to a federal initiative, a school clinician immunizes a child—but without parental consent.

News New bird flu strain kills two

New bird flu strain kills two

H7N9 influenza A, a strain of avian flu not previously known to infect humans, has sickened seven and killed two in China.

News Adjuvanted H1N1 flu vaccine linked to narcolepsy in kids

Adjuvanted H1N1 flu vaccine linked to narcolepsy in kids

British study shows link between European ASO3-adjuvanted pandemic influenza A H1N1 vaccine and narcolepsy risk.

News Pandemic flu vaccine safe in pregant women

Pandemic flu vaccine safe in pregant women

Vaccination with AS03-adjuvanted monovalent pandemic vaccine did not increase risk for stillbirth or other adverse birth outcomes.

News Flublok egg-free flu vaccine approved

Flublok egg-free flu vaccine approved

The FDA has approved a new cell-culture seasonal influenza vaccine that does not use live influenza virus or chicken eggs in its production.

News Influenza activity increasing across the U.S.

Influenza activity increasing across the U.S.

Influenza incidence has surpassed the 2011-2012 season, but associated mortality is below epidemic thresholds.

News High-dose flu vaccine better protects adults with HIV

High-dose flu vaccine better protects adults with HIV

Immunization with a trivalent influenza vaccine four times the strength of a standard dose conferred better protection in adults with HIV.

News FDA approves GSK quadrivalent flu vaccine

FDA approves GSK quadrivalent flu vaccine

The new flu vaccine will protect against two influenza A strains and two influenza B strains to limit the likelihood of a mismatch between the vaccine and circulating viruses.

News CDC: Flu season earliest in a decade

CDC: Flu season earliest in a decade

More severe disease, poorer outcomes expected with predominant influenza A H3N2 strain.

News Model accurately forecasts peak flu season

Model accurately forecasts peak flu season

Researchers were able to predict peak flu season seven weeks early, using a model that combines Google search terms with weather forecasting techniques.

Blog Post Eliminating barriers to the flu shot

Eliminating barriers to the flu shot

Time constraints make it difficult to adequately educate patients about the benefits of vaccines in the office, but there are several strategies that may help.

News First cell-culture flu vaccine approved

First cell-culture flu vaccine approved

The FDA has approved Flucelvax, the first seasonal flu vaccine using cell culture technology.

News AAP updates 2012-2013 flu vaccine recommendations

AAP updates 2012-2013 flu vaccine recommendations

New influenza vaccine recommendations from the American Academy of Pediatrics include two options for vaccine dosing in children ages 6 months through 8 years.

News Influenza H1N1 vaccine with adjuvant safe for pregnant women

Influenza H1N1 vaccine with adjuvant safe for pregnant women

Influenza A H1N1 vaccine not associated with birth defects, but linked to slight increased risk for Guillain-Barré syndrome.

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