November 2016 Issue of Clinical Advisor

November 2016 Issue of Clinical Advisor


Bipolar disorder treatment more effective in earlier stages

Treatment initiated in the early stages of bipolar disorder is more effective than treatment in later stages.

Binge-eating disorder: a review of effective treatment options

Cognitive behavioral therapy, lisdexamfetamine, second-generation antidepressants, and topiramate reduced binge eating.

Timolol effective treatment for infantile hemangiomas

Topical timolol maleate may be safe and effective for infantile hemangiomas, amid concerns about the potential overuse of propranolol.

Screening for preeclampsia recommended by USPSTF

The USPSTF releases a draft recommendation statement regarding preeclampsia screening in pregnant women.

Stepwise diabetes prevention effective in patients with prediabetes

Individuals with prediabetes may reduce their risk of diabetes with stepwise diabetes prevention.

Statin-based therapy less effective in advanced chronic kidney disease

Statin-based therapy had a smaller effect in reducing major vascular events in patients with advanced chronic kidney disease.

NCCPA survey results show PA certification continues to increase

The biggest challenges for recently certified PAs are the lack of clinical PA opportunities for recent graduates and the lack of clinical PA opportunities in ...

Hormonal contraception use associated with depression

Women who use hormonal contraception have an increased risk for first use of an antidepressant and first diagnosis of depression.

Reducing the duration of hepatitis C therapy may be effective

Shortening the duration of HCV therapy from 12 weeks to 3 weeks could substantially reduce the cost of treatment.

FDA requires black box warning on HCV drugs regarding potential HBV reactivation

The FDA issues a warning about the risk of hepatitis B virus reactivation among patients taking direct-acting antivirals to treat hepatitis C infections.

NSAID use linked to increased risk of heart failure hospitalization

Some individual NSAIDs may be linked to increased risk of hospital admission for heart failure.

Advisor Forum

Treatment tips for tinea pedis and yeast infections

Creams, sanitizers, and antiperspirant are all acceptable forms of treatment for tinea pedis and yeast infections.

Stopping the bleeding

Pressure on a wound is the key to stopping blood flow.

Vitamin D3 and type 1 diabetes

Vitamin D3 at 2000 IU reduced the incidence of type 1 diabetes by 88%.

Providing care for veterans exposed to Agent Orange

Evidence suggests that exposure to Agent Orange is linked with a number of serious and potentially fatal diseases.

Clinical Feature

Interventions in childhood obesity

Effective use of research-based interventions and recommendations for overweight and obese children begin with initiating a conversation with the family.

The role of biofilms in chronic infections

Bacteria in contact with living tissues form layers that resist penetration by the immune system or antibiotics, but promising treatments abound.


Recertifying from inactive status

For the APN who is recertifying, it is important to establish relationships with other APNs at the local and national level.

Alternative Meds Update

Vitamin K

Foods are the preferred source of vitamin K; however, supplements are widely available in many subtypes.

Stat Consult

Celiac disease

In celiac disease, the surface pattern of the jejunal mucosa becomes flattened.

Legal Advisor

Outdated vaccine protocol

A child deals with the consequences of a lesser vaccine, because a medical practice did not update its immunization policies.

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