Menopause

Comparing Osteoporosis Screening, Treatment Strategies in Postmenopausal Women

Comparing Osteoporosis Screening, Treatment Strategies in Postmenopausal Women

The need for effective osteoporosis screening tools and treatment strategies is high, as the current methods have a low sensitivity for determining postmenopausal women at risk for a major osteoporotic fracture.

Topical Methyl Estradiolpropanoate Safe, Effective for Treating Estrogen-Deficient Skin

Topical Methyl Estradiolpropanoate Safe, Effective for Treating Estrogen-Deficient Skin

A study was conducted to assess the safety, tolerability, and efficacy of methyl estradiolpropanoate, a topical soft estrogen cosmeceutical for the treatment of estrogen-deficient skin.

Postmenopausal Women With Normal BMI May Still Be at Increased Risk for Breast Cancer

Postmenopausal Women With Normal BMI May Still Be at Increased Risk for Breast Cancer

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Postmenopausal women with normal BMI and elevated body fat levels are at increased risk of breast cancer.

Food Deprivation During Fetal Development Linked to Early Menopause, Premature Ovarian Failure

Food Deprivation During Fetal Development Linked to Early Menopause, Premature Ovarian Failure

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Women born during the Chinese famine period may be at increased risk for early natural menopause and premature ovarian failure.

Menopausal Hormone Therapy May Reduce Carpal Tunnel Syndrome Risk

Menopausal Hormone Therapy May Reduce Carpal Tunnel Syndrome Risk

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To investigate the association between hormone therapy and carpal tunnel syndrome risk, researchers conducted a secondary analysis of the Women's Health Initiative (WHI) hormone therapy trials.

Sleep Quality in Women With Surgical vs Natural Menopause

Sleep Quality in Women With Surgical vs Natural Menopause

Women who undergo surgical menopause have significantly worse sleep quality than those who experience natural menopause.

History of Partner Violence Tied to Menopause Symptoms

History of Partner Violence Tied to Menopause Symptoms

History of sexual assault and current PTSD also associated with higher risk for menopause symptoms.

Severe Symptoms of Vulvovaginal Atrophy Associated With Reduced Quality of Life

Severe Symptoms of Vulvovaginal Atrophy Associated With Reduced Quality of Life

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Severity of symptoms of vulvovaginal atrophy in postmenopausal women was found to have an impact on quality of life.

Healthy Diet Associated With Reduced Menopausal Symptoms

Healthy Diet Associated With Reduced Menopausal Symptoms

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A diet high in fruits, vegetables, nuts, and legumes was found to be associated with a lower risk for physical, mental, and genitourinary symptoms of menopause compared with a diet high in fats, meats, desserts, and salts.

Early Menopause Associated With Shorter Life Expectancy, Early Diagnosis of Type 2 Diabetes

Early Menopause Associated With Shorter Life Expectancy, Early Diagnosis of Type 2 Diabetes

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Early age of menopause development is associated with lower overall life expectancy and fewer years of life without diabetes.

Functional Disability Progression More Rapid in Postmenopausal Women With RA

Functional Disability Progression More Rapid in Postmenopausal Women With RA

Functional disability progressed more rapidly in postmenopausal compared with premenopausal women with rheumatoid arthritis.

Tissue-Selective Estrogen Complex May Benefit Postmenopausal Women With Vaginal Bleeding, Breast Discomfort

Tissue-Selective Estrogen Complex May Benefit Postmenopausal Women With Vaginal Bleeding, Breast Discomfort

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Switching to tissue-selective estrogen complex from hormone therapy may benefit women with breast discomfort or vaginal bleeding.

Bijuva Approved for Moderate to Severe Vasomotor Symptoms From Menopause

Bijuva Approved for Moderate to Severe Vasomotor Symptoms From Menopause

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Approval from the Food and Drug Administration (FDA) was supported by the Phase 3 Replenish trial which evaluated the safety and efficacy of Bijuva in generally healthy, postmenopausal women with a uterus for the treatment of moderate to severe hot flashes.

Atherosclerosis Progression Differs According to Timing of Estradiol Therapy After Menopause

Atherosclerosis Progression Differs According to Timing of Estradiol Therapy After Menopause

Higher levels of estradiol were inversely associated with carotid artery intima-media thickness progression in the early postmenopausal cohort but positively associated with it in the late postmenopausal group.

Weight Loss May Reduce Breast Cancer Risk in Postmenopausal Women

Weight Loss May Reduce Breast Cancer Risk in Postmenopausal Women

Postmenopausal women with weight loss have a reduced risk for breast cancer.

Disorders in Pregnancy May Increase Risk for Hot Flashes During Menopause

Disorders in Pregnancy May Increase Risk for Hot Flashes During Menopause

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Hypertensive disorders of pregnancy and gestational diabetes may increase the risk for hot flashes during menopause.

Light Therapy Offers Nonpharmacologic Treatment for Perimenopausal Depression

Light Therapy Offers Nonpharmacologic Treatment for Perimenopausal Depression

Light treatments successfully corrected abnormal timing of melatonin circadian rhythms in perimenopausal women with depression and improved mood and sleep within 2 weeks.

Physical Activity as a Lifestyle Factor Influencing Early Menopause

Physical Activity as a Lifestyle Factor Influencing Early Menopause

Researchers concluded that physical activity was not associated with risk for early menopause.

Imvexxy Now Available in 4mcg Dosage Strength for Dyspareunia Due to Menopause

Imvexxy Now Available in 4mcg Dosage Strength for Dyspareunia Due to Menopause

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According to the Imvexxy prescribing information, women should generally be started at the 4mcg dosage strength with dosage adjustment guided by clinical response.

Guidelines for Managing Perimenopausal Depression Now Available

Guidelines for Managing Perimenopausal Depression Now Available

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The 5 topics addressed by the 11-member expert panel include epidemiology, clinical presentation, therapeutic effects of antidepressants, effects of hormone therapy, and the effectiveness of other therapies (eg, psychotherapy, exercise, natural health products).

Breastfeeding Linked to Lower Risk of Stroke Post-Menopause

Breastfeeding Linked to Lower Risk of Stroke Post-Menopause

Stroke risk 19% lower with breastfeeding for 1 to 6 months; stronger link for longer duration.

Genitourinary Syndrome of Menopause:  A Consensus Statement From the ISSWSH

Genitourinary Syndrome of Menopause: A Consensus Statement From the ISSWSH

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The International Society for the Study of Women's Sexual Health convened an expert consensus panel to discuss the use of androgens in the management of genitourinary syndrome of menopause.

Characteristics of Menstrual Cycle Associated With Early Natural Menopause

Characteristics of Menstrual Cycle Associated With Early Natural Menopause

Investigators examined the relationship between menstrual cycle characteristics in adolescence and early adulthood and the risk for early natural menopause.

No Impact on Carotid Artery Intima-Media Thickness Following Cessation of Menopausal Hormone Therapy

No Impact on Carotid Artery Intima-Media Thickness Following Cessation of Menopausal Hormone Therapy

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A follow-up study from KEEPS found that cessation of menopausal hormone therapy did not change the expected trajectory of carotid artery intima-media thickness over a 3-year period.

Ectopic Lipid Deposition and Insulin Resistance Higher in Postmenopausal Women

Ectopic Lipid Deposition and Insulin Resistance Higher in Postmenopausal Women

The insulin sensitivity in post- and premenopausal women along with lipid deposition in the liver and skeletal muscle was examined.

Menopause Transition Often Prompts Changes in Migraine Pattern, Characteristics

Menopause Transition Often Prompts Changes in Migraine Pattern, Characteristics

This retrospective study sought to assess migraine patterns in 69 menopausal women between ages 40 and 60 who were treated at Partners Healthcare Hospitals for concurrent migraine headache.

Reproductive Dysfunction Risk in Women Taking Long-Term Opioids for Musculoskeletal Pain

Reproductive Dysfunction Risk in Women Taking Long-Term Opioids for Musculoskeletal Pain

Women prescribed long- vs short-term opioids for chronic musculoskeletal pain may be at increased risk for menopause and abnormal menstruation.

Menopausal Hormone Therapy Slows Cognitive Decline in Postmenopausal Women

Menopausal Hormone Therapy Slows Cognitive Decline in Postmenopausal Women

Hormone therapy in postmenopausal women with mild cognitive impairment was examined.

No Additional Benefits With Vaginal Estradiol Tablets, Moisturizers for Postmenopausal Vulvovaginal Symptoms

No Additional Benefits With Vaginal Estradiol Tablets, Moisturizers for Postmenopausal Vulvovaginal Symptoms

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Prescribed vaginal estradiol tablets and over-the-counter vaginal moisturizers may not be more effective than placebos for postmenopausal vulvovaginal symptoms.

Nutraceuticals Containing Equol May Be Effective for Postmenopausal Symptoms

Nutraceuticals Containing Equol May Be Effective for Postmenopausal Symptoms

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Equol-containing nutraceuticals may be beneficial for postmenopausal women with vaginal symptoms.

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