Mood Disorders

Combinatorial Pharmacogenetics Useful in Treatment for Depression

Combinatorial Pharmacogenetics Useful in Treatment for Depression

These data support the clinical use of combinatorial pharmacogenetics for patients with major depressive disorder.

Age of Onset of Bipolar Disorder Linked With Substance Use Disorders

Age of Onset of Bipolar Disorder Linked With Substance Use Disorders

Older adults with bipolar disorder may benefit from a detailed assessment of the use of substances.

Bipolar Disorder Knowledge Scale Shows Internal Consistency and Reliability

Bipolar Disorder Knowledge Scale Shows Internal Consistency and Reliability

A 25-item true and false questionnaire was used to assess knowledge of bipolar disorder.

Novel Psychological Intervention Feasible, Acceptable for Treating Anxiety in Bipolar Disorder

Novel Psychological Intervention Feasible, Acceptable for Treating Anxiety in Bipolar Disorder

Personal recovery improved more rapidly for participants in the anxiety in bipolar disorder intervention, but not social and personal functioning.

Testing the Current Guidelines for Antidepressant Treatment of New Onset Depression

Testing the Current Guidelines for Antidepressant Treatment of New Onset Depression

Investigators determined that titrating sertraline to 100 mg/day vs 50 mg/day for initial antidepressant therapy for a new MDD episode has no added benefit and increases cost.

TMS Device Cleared to Treat Obsessive Compulsive Disorder

TMS Device Cleared to Treat Obsessive Compulsive Disorder

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Transcranial magnetic stimulation (TMS) uses magnetic fields to stimulate nerve cells in the brain.

Parental Depression Ups Odds of Child Use of Health Services

Parental Depression Ups Odds of Child Use of Health Services

Findings seen across spectrum of care -- outpatient, emergency department, inpatient.

Does Bipolar I Disorder Effect the Course of Conduct/Antisocial Personality Disorders in Adolescents?

Does Bipolar I Disorder Effect the Course of Conduct/Antisocial Personality Disorders in Adolescents?

Adolescents with bipolar I disorder whose symptoms are in remission are significantly less likely to experience conduct disorder or antisocial personality disorder.

FAST Scores for Functioning Are Meaningful for Recovery in Bipolar Disorder

FAST Scores for Functioning Are Meaningful for Recovery in Bipolar Disorder

There is no distinct cut off for the Functional Assessment Short Test between none, mind, moderate, and severe functional impairment.

Once-Monthly Perseris Approved for the Treatment of Schizophrenia

Once-Monthly Perseris Approved for the Treatment of Schizophrenia

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Perseris, an atypical antipsychotic, has an extended-release delivery system that releases sustained levels of risperidone over 1 month.

Lithium Use During Pregnancy Linked to Infant, Maternal Health Risks

Lithium Use During Pregnancy Linked to Infant, Maternal Health Risks

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Maternal lithium use in the first trimester of pregnancy may increase the risk for infant malformations.

Prenatal Depression More Common in Young Moms Today

Prenatal Depression More Common in Young Moms Today

Depressed mood more common in young pregnant women today than in their mothers' generation.

Differences Between Cyclothymic Disorder and Unspecified Bipolar Disorder in Youth May Indicate Course of Disorder

Differences Between Cyclothymic Disorder and Unspecified Bipolar Disorder in Youth May Indicate Course of Disorder

Investigators sought to determine the differences between youth with cyclothymic disorder and bipolar disorder not otherwise specified.

Screening for Tardive Dyskinesia Associated with Antipsychotic Treatment

Screening for Tardive Dyskinesia Associated with Antipsychotic Treatment

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Patients receiving treatment with antipsychotic agents would benefit from screening for tardive dyskinesia as these repetitive movements can negatively affect quality of life.

Regular Repeated Assessments Align Self-Reports, Case Manager Reports in Schizophrenia

Regular Repeated Assessments Align Self-Reports, Case Manager Reports in Schizophrenia

Repeated assessments improved the patients' ability to assess their own situation and the case workers' understanding of the patients' situations.

Childhood Abuse Linked to Compromised White Matter Integrity in Bipolar Disorder

Childhood Abuse Linked to Compromised White Matter Integrity in Bipolar Disorder

These findings are in line with previous research, which suggested that abuse and neglect in childhood have different effects on the brain.

Medication Adherence Predictors in Patients With Severe Psychiatric Disorders

Medication Adherence Predictors in Patients With Severe Psychiatric Disorders

As antipsychotic medications are vital to the effective management of severe psychiatric disorders, investigators sought to examine reasons for medication nonadherence in patients with schizophrenia, bipolar disorders, and other psychotic disorders.

Schizophrenia, Major Depressive Disorder, Bipolar Disorder Linked With Abnormal Functional Connectivity

Schizophrenia, Major Depressive Disorder, Bipolar Disorder Linked With Abnormal Functional Connectivity

Local functional connectivity may serve as neuroimaging marker to investigate the human brain connectome.

Prenatal antidepressant exposure may increase risk of poor motor development

A meta-analysis of 18 studies examining the association of prenatal antidepressant exposure with motor development in children showed a small overall effect of worse motor development outcomes among children exposed to antidepressants in pregnancy.

Medications with depression as a possible adverse effect associated with increased depression risk

In this cross-sectional study, the use of medications with depression as an adverse effect was associated with a higher prevalence of depression while a similar association was not observed for medications without depression as a possible side effect.

Depression an Adverse Effect in One-Third of Prescription Medications

Depression an Adverse Effect in One-Third of Prescription Medications

Prevalence of depression higher for adults reporting use of multiple meds with depression as side effect

Personality Disorders Related to Adverse Outcomes in Bipolar Disorder

Personality Disorders Related to Adverse Outcomes in Bipolar Disorder

These data may lead to a more nuanced understanding of bipolar disorder and to a better definition of the effectiveness of interventions directed at treating both personality disorders and bipolar disorder.

Older Age Tied to Poorer Course of Major Depressive Disorder

Older Age Tied to Poorer Course of Major Depressive Disorder

Results were slightly attenuated but remained mostly significant with adjustment for prognostic factors

Recommendations for Psychological Treatment of Anxiety in Primary Care

Recommendations for Psychological Treatment of Anxiety in Primary Care

Increased implementation of integrated primary care could help to improve the availability of psychological treatment for this patient population.

Social Media and Adolescents: What Are the Health Risks?

Social Media and Adolescents: What Are the Health Risks?

Primary care providers should screen for depression and other health-related risks associated with the use of social media by adolescents.

Long-Term Antidepressant Use Linked to Weight Gain

Long-Term Antidepressant Use Linked to Weight Gain

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The broad use of antidepressants among the general population may be linked to weight gain.

When Antidepressants Fail, Dose Increase May Be a Less Effective Response

When Antidepressants Fail, Dose Increase May Be a Less Effective Response

As this and previous research on dose increase strategies have produced inconsistent findings, the researchers recommended clinicians consider other responses to antidepressant treatment failure, at least for selective serotonin reuptake inhibitors.

Consensus Statement: Managing Bipolar Disorder During and After Pregnancy

Consensus Statement: Managing Bipolar Disorder During and After Pregnancy

Investigators summarize data regarding the management of bipolar disorder during pregnancy and in the postpartum period.

Using Buddhism-Based Compassion Training to Combat Compassion Fatigue

Using Buddhism-Based Compassion Training to Combat Compassion Fatigue

Compassion fatigue can lead to decreased quality of patient care and increases in medical errors.

Major Depression in Males May Lower Chances of Conception

Major Depression in Males May Lower Chances of Conception

Active major depression in women not associated with negative fertility outcomes.

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