Nephrology Information Center Archive

Job Market for Nephrologists Continuing to Improve

Job Market for Nephrologists Continuing to Improve

The job market for new nephrologists is continuing to improve, and most fellows would recommend nephrology to medical students or residents.

Lixisenatide Cuts Kidney Damage in Type 2 Diabetes and Coronary Syndrome

Lixisenatide Cuts Kidney Damage in Type 2 Diabetes and Coronary Syndrome

Lixisenatide reduces progression of urinary albumin-creatinine ratio in patients with macroalbuminuria.

Increasing Water Intake May Reduce Cystitis Recurrence

Increasing Water Intake May Reduce Cystitis Recurrence

For women at high risk for cystitis recurrence who drink low volumes of fluid daily, increasing water intake prevents recurrence.

High Susceptibility Antibiotics Reduce Readmission Rates for Urinary Tract Infections

High Susceptibility Antibiotics Reduce Readmission Rates for Urinary Tract Infections

The use of a moderate to low susceptibility antibiotic to treat a urinary tract infection [UTI] may result in a 1.74-fold increase in the odds of an emergency department readmission within 30 days for another UTI.

Proton Pump Inhibitor Use Tied to Hip Fracture in Dialysis Patients

Proton Pump Inhibitor Use Tied to Hip Fracture in Dialysis Patients

Correlation between PPI and hip fracture persisted for subgroups with low, medium, high PPI use.

Enlarged Kidneys in Neonates With Congenital Heart Disease

Enlarged Kidneys in Neonates With Congenital Heart Disease

Kidneys of neonates with left heart obstruction consistently found to be larger than normal.

WPSI Recommends Annual Urinary Incontinence Screening

WPSI Recommends Annual Urinary Incontinence Screening

Due to limited evidence, other experts urge caution in implementing guideline for women.

AAP Outlines Appropriate Pediatric Nephrology Testing

AAP Outlines Appropriate Pediatric Nephrology Testing

Five evidence-based recommendations list tests, procedures that doctors, patients should question.

Good Outcomes for HCV-Negative Recipients of HCV Kidneys

Good Outcomes for HCV-Negative Recipients of HCV Kidneys

All 20 recipients experienced HCV cure, good quality of life, excellent renal function.

Ethical Guidelines for Living Donor Transplantation

Ethical Guidelines for Living Donor Transplantation

The Belmont Report provides an appropriate framework for living donor organ transplantation.

Higher Visceral Fat Ratio Seen With Recurring Urolithiasis

Higher Visceral Fat Ratio Seen With Recurring Urolithiasis

No differences seen with other fat volume measures between recurring, first-time stones.

FDA Permits Marketing of Devices to Create Arteriovenous Fistula

FDA Permits Marketing of Devices to Create Arteriovenous Fistula

Two devices designed to create arteriovenous fistula in patients with CKD in need of hemodialysis

Study Compares Treatment Options for T1a Renal Cancer

Study Compares Treatment Options for T1a Renal Cancer

Percutaneous ablation compared with partial, radical nephrectomy for 4,310 patients aged 66 years

Pediatric Kidney Recipients Often Have Subclinical Inflammation

Pediatric Kidney Recipients Often Have Subclinical Inflammation

Associated with increased risk of composite end point of acute rejection, allograft failure

More Rapid Decline in Kidney Function for Diagnosed Diabetes

More Rapid Decline in Kidney Function for Diagnosed Diabetes

Much steeper decline in adjusted mean eGFR for those with diagnosed diabetes versus those without

UTI Guideline Implementation Improves Diagnoses in Postop Orthopedic Patients

UTI Guideline Implementation Improves Diagnoses in Postop Orthopedic Patients

Implementing a urinary tract infection quality improvement program resulted in a decrease in UTI diagnoses in orthopedic patients.

Sofosbuvir Improves Renal Safety in Patients With Chronic Hepatitis C

Sofosbuvir Improves Renal Safety in Patients With Chronic Hepatitis C

Patients with mild, moderate renal impairment showed improvement in renal biomarkers over one year

Acute Kidney Injury in Hospital Ups Risk of Later Heart Failure

Acute Kidney Injury in Hospital Ups Risk of Later Heart Failure

Findings based on one-year follow-up after a hospitalization complicated by acute kidney injury

Increased Water Consumption Does Not Enhance Kidney Function in Chronic Kidney Disease

Increased Water Consumption Does Not Enhance Kidney Function in Chronic Kidney Disease

Trained water consumption increase does not significantly reduce the decline of kidney function in individuals with chronic kidney disease.

Prophylaxis may protect kidney recipients from HCV

Prophylaxis may protect kidney recipients from HCV

Prophylaxis safely, effectively prevents HCV transmittance in noninfected patients receiving kidney transplants from HCV-positive donors.

AKI common after non-kidney organ transplants in children

AKI common after non-kidney organ transplants in children

Children who receive a non-kidney solid organ transplant have an increased risk for AKI in the first year after surgery and is associated with an increased risk of CKD.

Model uses acute kidney injury to predict chronic kidney disease

Model uses acute kidney injury to predict chronic kidney disease

A 6 variable model predicted advanced chronic kidney disease in patients with acute kidney injury.

Symptomatic treatment inferior to antibiotics in women with UTIs

Symptomatic treatment inferior to antibiotics in women with UTIs

Treating lower UTIs with diclofenac may help in optimizing antibiotic treatments.

FDA approves Vabomere for UTI treatment

FDA approves Vabomere for UTI treatment

This approval provides an additional treatment option for patients with complicated urinary tract infection.

Infection risk increases with reduced kidney function

Infection risk increases with reduced kidney function

Researchers observed excess community-acquired infections incidence in individuals with mild to severe chronic kidney disease.

Botulinum toxin may be safe and effective for overactive bladder

Botulinum toxin may be safe and effective for overactive bladder

Intradetrusor injection of onabotulinumtoxin A impairs afferent and efferent nerves, but an injection-free drug delivery approach only impairs the bladder afferent nerves.

Recurrent kidney stone formers may not benefit from 24-hour urine collection

Recurrent kidney stone formers may not benefit from 24-hour urine collection

It is unclear whether all recurrent kidney stone formers benefit from 24-hour urine collection.

FDA approves first drug for frequent urination at night

FDA approves first drug for frequent urination at night

Noctiva is designed to increase absorption of water through the kidneys, decreasing urine production.

Recommendations released for management of small renal masses

Recommendations released for management of small renal masses

Researchers used data from 83 studies to develop guideline for management of patients with small renal masses.

American Urological Association issues guideline for male urethral stricture

American Urological Association issues guideline for male urethral stricture

The guidelines provide a clinical framework for the diagnosis and treatment of male urethral stricture.

Low vitamin D levels increase risk for bladder cancer

Low vitamin D levels increase risk for bladder cancer

Low levels of vitamin D in the blood may prevent the cells within the bladder from stimulating an adequate response to abnormal cells.

New guideline for managing kidney stones is released

New guideline for managing kidney stones is released

Guideline from the American Urological Association has been revised to incorporate the management of patients with staghorn renal stones.

Renal function can predict preeclampsia in pregnant women with hypertension

Renal function can predict preeclampsia in pregnant women with hypertension

Baseline renal function tests may predict the risk of preeclampsia and preterm birth for pregnant women with hypertension.

Cultural considerations in diabetes: controlling HbA1c in a patient observing Ramadan

Cultural considerations in diabetes: controlling HbA1c in a patient observing Ramadan

A patient with type 2 diabetes is undergoing dialysis and needs to control his HbA1c levels while fasting during Ramadan.

COPD may increase risk for chronic renal failure

COPD may increase risk for chronic renal failure

In patients with COPD, chronic renal failure is more likely and can be detected from decreased glomerular filtration rates.

HIV treatments, immunosuppressants may interact in transplant patients

HIV treatments, immunosuppressants may interact in transplant patients

A renal transplant recipient experienced drug interaction-induced calcineurin inhibitor nephrotoxicity after starting a cobicistat-containing combination treatment for HIV.

Managing nephropathy in a patient with type 2 diabetes

Managing nephropathy in a patient with type 2 diabetes

A patient with type 2 diabetes presents with elevated microalbumin levels and a recent history of elevated glucose due to bedtime snacking.

CDC works to eliminate HCV transmission in hemodialysis

CDC works to eliminate HCV transmission in hemodialysis

The organization encourages dialysis providers to improve current infection control practices.

Kidney stones becoming more common among youth, women, African Americans

Kidney stones becoming more common among youth, women, African Americans

The annual incidence of kidney stones has increased 16% between 1997 and 2012

Online risk calculator predicts kidney failure odds in chronic kidney disease patients

Online risk calculator predicts kidney failure odds in chronic kidney disease patients

A new online risk calculation tool predicts kidney failure odds in patients with chronic kidney disease.

Ventricle pacing reduces heart failure in chronic kidney disease patients

Ventricle pacing reduces heart failure in chronic kidney disease patients

Researchers found a 15% to 20% reduction in the risk of hospitalization for or death from heart failure in patients who received cardiac resynchronization therapy with defibrillator (CRT-D).

Fever and tachycardia after a liver transplant

Fever and tachycardia after a liver transplant

A 29-year-old woman, 12 years post-liver transplant, presents with fever and tachycardia and had recently reported fatigue, weakness, and abdominal pain.

EKG metrics may signal risk for cardiovascular death in CKD patients

EKG metrics may signal risk for cardiovascular death in CKD patients

Five EKG parameters can identify chronic kidney disease patients at risk for cardiovascular death.

Hemodialysis patients can be trained to reduce fluid, salt intake

Hemodialysis patients can be trained to reduce fluid, salt intake

Training can help reduce fluid and salt intake in patients undergoing hemodialysis.

Preventing acute kidney injury

Preventing acute kidney injury

Monitoring kidney function in hospitalized patients can help prevent acute kidney injury.

Sugary beverages linked to nonalcoholic fatty liver disease

Sugary beverages linked to nonalcoholic fatty liver disease

People who drink more than one sugary beverage per day have an increased risk of developing NAFLD.

Ezetimibe not effective in treating NASH

Ezetimibe not effective in treating NASH

Ezetimibe did not outperform placebo in reducing liver fat in nonalcoholic steatohepatitis (NASH).

Additional evidence of link between psoriasis, kidney disease

Additional evidence of link between psoriasis, kidney disease

Patients with psoriasis should avoid long-term use of medications that are toxic to the kidneys.

Biologic therapy may be safe for hemodialysis patients with psoriasis

Biologic therapy may be safe for hemodialysis patients with psoriasis

Patient with psoriasis were unsuccessfully treated with conventional therapies before treatment with biologics.

Black urine after a spinning class

Black urine after a spinning class

After taking a spinning exercise class, a woman developed acute kidney injury.

Pediatric acute kidney injury intervention improves patient follow-up rates

Pediatric acute kidney injury intervention improves patient follow-up rates

The follow-up pathway utilizes trigger reports, tracking spreadsheets, and educational materials to improve patient satisfaction.

Renal failure in a patient with maturity onset diabetes of the young

Renal failure in a patient with maturity onset diabetes of the young

A patient presented to the office with a 45-year history of maturity onset diabetes of the young after renal failure.

Walking two minutes per hour may reverse negative effects of sitting

Walking two minutes per hour may reverse negative effects of sitting

Trading two minutes of sitting for two minutes of light-intensity activity each hour lowered the risk of premature death by 33%.

High water intake may decrease kidney stone risk

High water intake may decrease kidney stone risk

Patients who reported drinking a higher volume of water (at least 2.0 to 2.5 liters per day) were at a reduced risk for recurrent kidney stones.

Urine albumin-to-creatinine ratio is test of choice

Urine albumin-to-creatinine ratio is test of choice

Since 2002, the urine test of choice is a urine albumin-to-creatinine ratio (UACR), which is a spot urine test.

Diets high in meat, acid up kidney failure risk in CKD patients

Diets high in meat, acid up kidney failure risk in CKD patients

Those who consumed high-acid diets appeared to face triple the risk of kidney failure compared with those who consumed low-acid diets.

HIV-positive kidney transplantation results 'impressive'

HIV-positive kidney transplantation results 'impressive'

Of the 27 HIV-positive patients with kidney disease who received transplants from HIV-positive patients who had died, 74% were alive after five years.

High fiber intake may lower kidney stone risk in postmenopausal women

High fiber intake may lower kidney stone risk in postmenopausal women

There were no significant protective effects noted for fiber, fruit, or vegetable intake on the risk of kidney stone recurrence in women with a history of stones.

New drug combo wins FDA approval to treat UTIs, intra-abdominal infections

New drug combo wins FDA approval to treat UTIs, intra-abdominal infections

Ceftolozane/tazobactam is the fourth antibiotic to be FDA approved in 2014

Yellow lights, digoxin toxicity

Yellow lights, digoxin toxicity


A woman complaining of seeing yellow lights is diagnosed with digoxin toxicity.

Statin use advised in chronic kidney disease

Statin use advised in chronic kidney disease


A new study indicated that older patients with predialysis chronic kidney disease should take statins.

Low-sodium meats have higher potassium levels

Low-sodium meats have higher potassium levels

Potassium-containing additives were listed in the ingredients in 63% of sodium-reduced products and 25% of non-reduced products.

Taking action against acute 
kidney injury in primary care

Taking action against acute 
kidney injury in primary care

With acute kidney injury often encountered in the outpatient setting, 
primary-care providers should know the basics of diagnosis and treatment.

Patient receives a kidney diagnosis and a life lesson

Patient receives a kidney diagnosis and a life lesson


Patient with back pain and blood in urine is diagnosed with autosomal dominant polycystic kidney disease.

Easy formula for identifying normal glomerular filtration rate

Easy formula for identifying normal glomerular filtration rate

Each patient loses 0.8% kidney function/year after the age of 30. If you round this to a loss of 1% per year (for simplicity), you can calculate if a GFR is normal for a patient's age.

Kidney donation OK for select seniors

Kidney donation OK for select seniors

The combined outcome of death/cardiovascular disease was not significantly different between donors and nondonors.

Chronic kidney disease linked to some cancers

Chronic kidney disease linked to some cancers

A history of reduced kidney function may put an individual at greater risk for developing renal and urothelial cancers.

CKD risk factors identified years before diagnosis

CKD risk factors identified years before diagnosis

Hypertension, obesity, diabetes and other risk factors were found in patients with chronic kidney disease years before diagnosis.

Kidney transplants linked to higher survival rates

Kidney transplants linked to higher survival rates

Compared with intensive home hemodialysis treatments, kidney transplant patients had better survival rates, but higher early rates of hospitalization.

Outcomes worse with HCV, HIV coinfection

Outcomes worse with HCV, HIV coinfection

Patients with both hepatitis C and HIV had higher rates of hepatic decompensation regardless of treatment with antiretroviral therapy than those with HCV alone.

Recurrent
 UTI therapies
 assessed

Recurrent
 UTI therapies
 assessed

Daily antibiotic use came out on top when compared with several other strategies for managing recurrent urinary tract infections (UTIs).

Nephrotoxic medications for patients on dialysis

Nephrotoxic medications for patients on dialysis

Can drugs that are contraindicated in patients with severe renal impairment be used in individuals with ESRD who are actively receiving hemodialysis?

Gout management 
in patients with CKD

Gout management 
in patients with CKD

The most recent guidelines from the American College of Rheumatology
include pharmacologic and nonpharmacologic therapy for hyperuricemia.

Kidney stones linked to heart disease in women

Kidney stones linked to heart disease in women

An examination of three longitudinal studies showed that women with a history of kidney stones, but not men, were more likely to have CHD.

Avoiding costly ­diagnostic mistakes

Avoiding costly ­diagnostic mistakes

How should a clinician 
handle a difference of 
opinion with the attending physician on duty?

Omontys recalled after reports of fatal reactions

Omontys recalled after reports of fatal reactions

All lots of the new anemia drug peginesatide have been recalled because of severe, sometimes fatal, hypersensitivity reactions.

Kidney guide features albuminuria testing

Kidney guide features albuminuria testing

Albuminuria levels help clinicians better stratify risk and evaluate likely outcomes.

Kidney decline linked with cognitive decline

Kidney decline linked with cognitive decline

Changes in renal functioning over time were associated with changes in global cognitive ability, verbal episodic memory and abstract reasoning.

First OTC drug approved for overactive bladder

First OTC drug approved for overactive bladder

The FDA has approved oxybutynin (Oxytrol, Merck) as the first over-the-counter treatment for women 18 and older with overactive bladder.

FDA expands Botox indication for overactive bladder

FDA expands Botox indication for overactive bladder

The FDA has approved Botox for adults with overactive bladder who can't use or don't respond to anticholinergics.

New paradigms in managing chronic kidney disease

New paradigms in managing chronic kidney disease

To slow the progression to end-stage renal disease, primary-care clinicians must be able to identify, screen, treat, and educate at-risk individuals.

Managing UTIs in women

Managing UTIs in women

Urinalysis and physical exam determine if the infection is complicated or uncomplicated, primary or recurrent and guide treatment strategy.

How common is vitamin overdose?

How common is vitamin overdose?

Many patients take vitamins that are more than 100% the recommended daily allowance. When do they begin to pose risks to kidney function?

Osteoporosis medications in patients with kidney disease


Is it safe to restart osteoporosis medications in patients with stage 5 chronic kidney disease?

Best procedure before ordering a radiologic study with contrast?

How much of a workup do you recommend before ordering diagnostics with contrast (assuming kidney function tests are normal)?

How is microalbumin:creatinine ratio interpreted?

How is microalbumin:creatinine ratio interpreted?

When is it appropriate to refer diabetic and hypertensive patients to a renal specialist?

Renal disease, diabetes linked to uric acid

Uncontrolled serum uric acid in patients with gout is associated with an increased risk of developing kidney disease and diabetes, according to the findings from two studies presented at the 2011 American College of Rheumatology Meeting.

Kidney mass detected on ultrasound doubles in size over nine months

Kidney mass detected on ultrasound doubles in size over nine months

Imaging was ordered when the patient's clinician could not palpate her ovaries.

Waistline may predict kidney patient's mortality risk

Clinicians should consider waist circumference in conjunction with BMI when assessing mortality risk among patients with chronic kidney disease.

Are ACE inhibitors and ARBs recommended for renal disease?

Tight glycemic, BP and cholesterol control, as well as weight reduction, exercise and smoking cessation can help prevent renal nephropathy.

Phenazopyridine as a treatment for UTI

If a woman has taken OTC phenazopyridine, and urine dipstick results are skewed, is it appropriate to treat empirically with antibiotics based on history and exam findings?

Use cystatin C to detect kidney problems

Cystatin C blood measurements may be useful in assessing the risk of complications associated with chronic kidney disease.

Primary care provider missed severe uremia

Patient visits her cardiologist complaining of dizziness and lightheadedness.

New technology aids glucose monitoring

New technology aids glucose monitoring

Designed to record blood sugar levels throughout the day, these devices spot trends that may go unnoticed with standard tests and measurements.

Anticoagulation on dialysis

How can I ensure that patients receiving dialysis maintain therapeutic anticoagulation while on warfarin?

Screening for microalbuminuria in patients with diabetic nephropathy

How does screening for microalbuminuria change the management of these patients?

HbA1c higher in blacks

HbA1c higher in blacks

Screening could have limited usefulness in reflecting glucose intolerance, predicting the risk of diabetes complications, and measuring quality of care.

Endoscopic surgery for fistula creation

Endoscopic surgery for fistula creation

A new, minimally invasive approach will decrease morbidity amonghemodialysis patients and help improve their quality of life.

Hospital not liable for kidney transplant cancer death

The case involved the death of a 37-year old man who died from cancer and receiving a kidney from a woman who had uterine cancer.

Kidney stones with osteopenia

Should patients with calcium oxalate kidney stones and osteopenia be given vitamin D and calcium?

Sign Up for Free e-newsletters