Neurocognitive Disorders

Combo Physical, Mental Activity Prevents Cognitive Decline

Combo Physical, Mental Activity Prevents Cognitive Decline

Benefits seen were greater than for social interaction alone in older black population.

Sensor Array May Detect De Novo Parkinson Disease in Breath

Sensor Array May Detect De Novo Parkinson Disease in Breath

Sensitivity, specificity, accuracy values of 79, 84, and 81% for detecting PD from controls.

Cognitive Impairment Profiles Differ Between Parkinson's, Alzheimer's

Cognitive Impairment Profiles Differ Between Parkinson's, Alzheimer's

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As the neurodegenerative processes of Alzheimer disease and Parkinson disease are different, early cognitive impairment also present differently in these diseases.

New Clinical Guideline for Evaluating Alzheimer's, Related Dementias

New Clinical Guideline for Evaluating Alzheimer's, Related Dementias

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Currently, there are no US consensus on best clinical practice guidelines that incorporate multispecialty recommendations for evaluating cognitive impairment that are thought to be due to Alzheimer's disease and Related Dementias (ADRD) for use by physicians and nurse practitioners.

Visual Function Deficits Up in Developmental Dyslexia

Visual Function Deficits Up in Developmental Dyslexia

Increased prevalence of deficits in visual function vs typically developing school-age children.

Retinal Nerve Fiber Layer Thickness May Be Associated With Cognitive Function

Retinal Nerve Fiber Layer Thickness May Be Associated With Cognitive Function

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Thinning of the retinal nerve fiber layer has been linked to worsening cognitive function and may be valuable in identifying individuals who may be at risk for cognitive decline.

Menopausal Hormone Therapy Slows Cognitive Decline in Postmenopausal Women

Menopausal Hormone Therapy Slows Cognitive Decline in Postmenopausal Women

Hormone therapy in postmenopausal women with mild cognitive impairment was examined.

Metabolic Health Predicative of Cognitive Development in Children

Metabolic Health Predicative of Cognitive Development in Children

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Researchers assessed whether current metabolic parameters are inversely associated with cognitive functioning.

Dementia, Alzheimer Disease Risk Increased With Lower Branched-Chain Amino Acid Levels

Dementia, Alzheimer Disease Risk Increased With Lower Branched-Chain Amino Acid Levels

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Lower BCAA levels may be associated with an increased risk of incident dementia.

Child Neuroblastoma Survivors at Risk for Psychological Impairment

Child Neuroblastoma Survivors at Risk for Psychological Impairment

Psychological impairment seen particularly in those with chronic health conditions

Long-Term Type 1 Diabetes Associated With Cognitive Decline

Long-Term Type 1 Diabetes Associated With Cognitive Decline

Deficits similar for long-term type 1 diabetes and age-matched patients with type 2 diabetes

Visual Test Improves Prediction of Dementia in Primary Care

Visual Test Improves Prediction of Dementia in Primary Care

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Administering a visual association test in patients with a small decline on the Mini-Mental State Examination during a 2-year period has substantial incremental value for identifying those at elevated risk for developing dementia.

Cannabis Use, Cognitive Functioning Link Small in Adolescents, Young Adults

Cannabis Use, Cognitive Functioning Link Small in Adolescents, Young Adults

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Associations between cannabis use and cognitive functioning in adolescents and young adults are small.

Multiple Sclerosis Guidelines: AAN's Recommendations for Initiating, Switching, Stopping Disease-Modifying Therapy

Multiple Sclerosis Guidelines: AAN's Recommendations for Initiating, Switching, Stopping Disease-Modifying Therapy

The new guidelines focus on helping clinicians decide when to initiate, switch, or discontinue disease-modifying therapies for multiple sclerosis.

Siponimod Reduces Risk for Disability Progression in Secondary Progressive MS

Siponimod Reduces Risk for Disability Progression in Secondary Progressive MS

Investigators believe the siponimod EXPAND study is the first trial of disease-modifying therapy to show superiority over a placebo for disability progression in SPMS.

Newly Proposed Definition of Alzheimer's Disease Focuses on Biologic Criteria

Newly Proposed Definition of Alzheimer's Disease Focuses on Biologic Criteria

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The NIA-AA has proposed updates to the 2011 guidelines for symptomatic stages of Alzheimer's disease to include the idea that certain imaging and cerebrospinal fluid biomarkers are valid proxies for neuropathologic changes of AD.

Cannabinoids May Decrease Seizure Frequency in Refractory Epilepsy

Cannabinoids May Decrease Seizure Frequency in Refractory Epilepsy

A reasonable proportion of patients with epilepsy who have received treatment with pharmaceutical-grade cannabidiol products along with antiepileptic drugs have experienced a decrease in seizure frequency.

High total cholesterol linked to lower risk of cognitive decline in elderly

High total cholesterol linked to lower risk of cognitive decline in elderly

Cognitive decline risk is lowered in individuals aged 85 and older with high cholesterol.

Cerebral palsy, epilepsy risk associated with lower Apgar score

Cerebral palsy, epilepsy risk associated with lower Apgar score

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An inverse relation was observed between epilepsy and cerebral palsy and 5-minute and 10-minute Apgar scores.

Long-term memory enhanced by electrical stimulation of the amygdala

Long-term memory enhanced by electrical stimulation of the amygdala

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Modulate electrical stimulation of the amygdala may improve declarative memory without provoking any emotional reaction.

NFL players do not have significantly increased mortality risk

NFL players do not have significantly increased mortality risk

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Among NFL football players who began their careers between 1982 and 1992, career participation in the NFL, compared with limited NFL exposure obtained primarily as an NFL replacement player during a league-wide strike, was not associated with a statistically significant difference in long-term all-cause mortality.

Solanezumab does not change cognitive decline in mild Alzheimer’s disease

In patients with mild Alzheimer's disease solanezumab, an antibody designed to facilitate clearance of amyloid-beta plaques, did not significantly reduce cognitive decline over time.

Green leafy vegetable consumption linked to slower cognitive decline

Green leafy vegetable consumption linked to slower cognitive decline

Intake of primary nutrients and bioactives in green leafy vegetables is associated with slower cognitive decline.

Pesticides and 
Parkinson's disease

Pesticides and 
Parkinson's disease

Increasing evidence has shown a link between pesticide exposure and the risk for Parkinson's disease. How real is this link on the golf course?

The bravery of people with dementia

The bravery of people with dementia

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Facing dementia with strength and courage can inspire and comfort patients' families.

Predicting neurodevelopmental outcomes in children with very low birth weight

Predicting neurodevelopmental outcomes in children with very low birth weight

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Four main factors can be used to predict potential neurodevelopmental delays in children born prematurely.

Increasing weight loss linked to mild cognitive impairment in older adults

Increasing weight loss linked to mild cognitive impairment in older adults

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People who lose greater amounts of weight per decade later in life have an increased risk of mild cognitive impairment.

Moderate coffee intake may reduce cognitive impairment

Moderate coffee intake may reduce cognitive impairment

Older adults who consumed a moderate amount of coffee had a lower risk of mild cognitive impairment.

Cost of autism care may reach $500 billion by 2025

Cost of autism care may reach $500 billion by 2025

Researchers estimate that the annual cost of caring for people with autism spectrum disorder could rise to $500 billion to $1 trillion.

Mediterranean diet and cognition

Mediterranean diet and cognition

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Adhering to a Mediterranean diet may help fight against cognitive decline in older adults.

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