Neurology Information Center News
American Headache Society Releases Position Statement on Novel Preventive and Acute Migraine Treatments
The American Headache Society has issued updated guidelines on the use of novel preventive and acute treatments for migraine in adults.
African-Americans have lower mean CSF concentration of total tau, phosphorylated tau181.
While evidence-based guidelines exist for the determination of brain death in infants, children, and adults, Nevada is currently the only state to adopt laws that require adherence to these guidelines.
Pregnant women presenting with migraine to acute care settings were found to be treated with therapeutic agents ranging from safe and effective medications to others with unclear efficacy and potential teratogenicity.
Association seen in patients with cerebral palsy without accompanying intellectual disability.
Vitamin D3 may reduce migraine days in patients who experience frequent migraines.
Cluster headache and migraine are distinct primary headache disorders that are associated with substantial pain and disability.
Requip and Requip XL are non-ergot dopamine agonists indicated for the treatment of Parkinson disease.
Overall, 28.8 million disability-adjusted life years due to dementia; 6.4 million attributed to modifiable risks.
Risk increased for youth with depression or history of concussion.
Migraine with aura is associated with an elevated risk for incident atrial fibrillation.
In the Phase 3 JET8 study (N=318), patients underwent a circadian challenge of 8 hours in advance to their usual bedtime.
Estimated risk from age 25 years onward is 24.9%, with geographic variation in risk.
OCT probe integrated into standard brain biopsy needle IDs vessels with high sensitivity, specificity.
No subjective memory decline observed in association with cardiac surgery in older adults.
The comorbid presence of central apnea has been identified by multiple researchers as predictive of SUDEP.
Prevalence of active migraine decreased linearly in the 24 years prior to diabetes diagnosis.
Brain atrophy does not appear to mediate the diabetes-cognition relationship.
Left hemisphere dominates sensory visceral integration, right tied to the autonomic function.
Amoeba entered the upper nasal cavity and then the bloodstream, eventually reaching the brain.
Odds of both ASD and ADHD increased for later-born siblings of children with either diagnosis.
In adjusted analysis, smoking tied to worse symptom severity, sleep problems, anxiety, depression.
Subsequent risk increased with infections requiring hospitalization, treatment with anti-infective agents.
Women who undergo surgical menopause have significantly worse sleep quality than those who experience natural menopause.
Researchers examined a database of seizure-related deaths to determine whether cause was drowning or sudden unexpected death in epilepsy.
As of Nov. 30, 134 cases of AFM have been confirmed in 33 states.
70 percent of children with current ASD are treated; 20.3% receive behavioral treatment and medication.
The investigators sought to evaluate the prevalence of migraines, as well as the effect of sex and stress on migraines.
Those with a low risk for SUDEP generally remain in this categorization during 3 years of tracking.
Sex does not independently predict burnout, fatigue, overall quality of life after controlling for age.
Monitoring mandibular movement reflects efficacy of oral appliance therapy in obstructive sleep apnea.
Study is the first to document the utility of liquid biopsy in a pediatric brain tumor population.
Patients receiving GAD gene therapy develop unique treatment-dependent polysynaptic brain circuit.
Lower perception of scholastic, social, athletic competence could affect reading, motor skills.
Total of 16,583 cases identified in 2015 using National Amyotrophic Lateral Sclerosis Registry.
Adjustment for subclinical brain disease markers did not reduce link between arterial stiffness, dementia.
Crude mortality rates for individuals with dementia were 5 times higher than for those without.
Rise seen in postinjury rate of mental health diagnoses; suicide rate higher than population average.
The results highlight the importance of evaluating and monitoring cognitive function in individuals with recent critical illness or major infections, especially if they are already at risk for dementia.
252 patients currently under investigation for AFM, an increase of 33 patients since last week.
The new guidelines will facilitate the design and development of clinical trials to test new therapies to minimize the burden of neurologic disability produced by neurosarcoidosis.
Among college football players, number, severity of head impacts may affect risk for concussion.
Researchers and pain experts formulated guidelines for the use of onabotulinumtoxinA for the management of chronic migraine.
Level of S100B up after sports-related concussion, especially within 4 hours of concussion.
Patients with both Parkinson disease and type 2 diabetes were more likely to have cardiovascular comorbidities than those with only Parkinson disease.
Approximately 5.5 million Americans have Alzheimer disease or dementia.
Neurological and neuropsychological examinations were performed to assess intellectual disabilities, and biological assays were performed on collected CSF and plasma.
A 2016 experimental rule change in National Collegiate Athletic Association (NCAA) Division I Ivy League play has been linked to a reduction in concussions among players.
Multiple system atrophy is a rare, progressive neurodegenerative condition for which there is currently no cure.
Genetic and lifestyle factors are independently associated with incident stroke among men and women aged 40 to 73 years.
One in 2 women and 1 in 3 men will develop dementia, stroke, or parkinsonism during their lifetime.
Itch is "learned" in the nervous system, said Dr Berger, with involvement by both central and peripheral neural processes.
Findings among individuals with a genetic mutation known to cause Alzheimer's.
Researchers analyze the dietary habits of 260 patients in the early stages of multiple sclerosis from baseline to 5 years after initial onset of symptoms.
The Get With the Guidelines-Stroke program includes measures such as neurologist assessment, rehabilitation evaluation, and education on stroke risk factors.
Safety data for Fycompa was consistent with the safety profile in adult populations without the need for weight-based dosing.
The new guidelines place a substantial emphasis on the importance of introducing high-quality rehabilitation early in these patients.
For children, infants with febrile seizure, recurrence down with acetaminophen vs no antipyretic.
Benefits include better functional health, sleep-related quality of life, psychological well-being.
The Company states that the NDA is supported by robust clinical trial data, including patients studies where more than 1600 seizures were treated with Valtoco nasal spray.
The odds of language delay were lower at 18 months and 36 months in children exposed to AEDs in utero whose mothers took folic acid.
The risk for late-onset epilepsy was lower in patients with higher physical activity levels and moderate alcohol intake.
Recurrence of seizures was reported in 28.2% of patients who attempted withdrawal.
Approximately 28% of stroke patients have diabetes, and the presence of diabetes can increase the risk for poor stroke outcome.
Short sleep duration linked to reduced risk for black men; risk up for white men with long sleep duration.
Light treatments successfully corrected abnormal timing of melatonin circadian rhythms in perimenopausal women with depression and improved mood and sleep within 2 weeks.
Emergency department computed tomography rates for children with minor head trauma were not affected by parent decision aid use.
More than 2 hours of recreational screen time was found to be associated with cognitive decline in children.
This research rejects any association between increased risk for ADHD and changes in children's microbiota related to cesarean delivery or antibiotic use.
Alzheimer's disease and related dementias burden is expected to increase to 3.3% in 2060.
Investigators examined the effects of smoking on respiratory symptoms and functional levels in patients with multiple sclerosis.
Three factors help identify absolute 10-year risk of Alzheimer's disease, all dementia for different groups.
Although 2 patients experienced an increase in seizure frequency, the remaining patients did not experience a change in frequency.
MRIs show rheumatoid arthritis patients have neurobiologic features observed in fibromyalgia.
The consumption of whole-fat dairy products may reduce cardiovascular disease and mortality risk, contrary to current dietary guidelines that advise limited consumption of fat-free or low-fat dairy products.
Gradually increasing academic pursuits requires careful planning among the medical, school, and family units to enable prompt return and avoidance of prolonging school absence.
CT scans may be warranted in the case of vomiting, unconsciousness, and severe, worsening headaches.
Significant increases in prevalence in subgroups by age, sex, race/ethnicity, income, geographic region.
Among adult survivors of stroke, Medicaid increased, non-adherence decreased after ACA implementation.
Patients with atrial fibrillation who have ≥1 non-sex CHA2DS2VASc stroke risk factor should receive oral anticoagulation as antithrombotic therapy.
Raising Awareness of Pseudobulbar Affect: Knowing the Signs, Symptoms, and Treatment for Patients With Uncontrollable Laughing or Crying
Pseudobulbar affect is a significant national health issue in the United States, with approximately 2 million individuals affected.
Although literature indicates bidirectional associations between sleep disturbances and pain, few longitudinal studies have examined the role of sleep disturbances in contributing to chronic pain.
Sensitivity, specificity, accuracy values of 79, 84, and 81% for detecting PD from controls.
An expert subcommittee was formed consisting of members of the AAN and AES to update the 2004 evidence-based guidelines on epilepsy treatment with AEDs.
The majority of patients with cancer who are being treated with World Health Organization Step III opioids were found to experience poor sleep quality, often due to pain.
Increased suicide risk with one, two, and three or more medical contacts for traumatic brain injury.
Increased dementia risk for those with abstinence or with drinking 14 units alcohol/week in midlife.
Poorer quality sleep for children, parents attributed to high levels of noise.
As the neurodegenerative processes of Alzheimer disease and Parkinson disease are different, early cognitive impairment also present differently in these diseases.
Currently, there are no US consensus on best clinical practice guidelines that incorporate multispecialty recommendations for evaluating cognitive impairment that are thought to be due to Alzheimer's disease and Related Dementias (ADRD) for use by physicians and nurse practitioners.
Respiratory polygraphy can accurately diagnose sleep apnea in patients hospitalized with heart failure.
Increased prevalence of deficits in visual function vs typically developing school-age children.
Causes of death in patients with epilepsy were assessed to determine the presence of cardiac pathology.
Investigators examined rates, predictors, and outcomes of neuroimaging in pediatric and adolescent patients who presented to the ED with a headache.
This retrospective study sought to assess migraine patterns in 69 menopausal women between ages 40 and 60 who were treated at Partners Healthcare Hospitals for concurrent migraine headache.
Thinning of the retinal nerve fiber layer has been linked to worsening cognitive function and may be valuable in identifying individuals who may be at risk for cognitive decline.
DBS has been known to generate other movement-related disorders such as dyskinesias, blepharospasm, and hypokinesia.
Current oral contraceptive products contain lower doses of estrogen than those used in the past, prompting reconsideration of risks and benefits.
Hormone therapy in postmenopausal women with mild cognitive impairment was examined.
Investigators examined the incidence and outcomes of pneumonia in patients with acute ischemic stroke and type 2 diabetes.