Neurology

Mental Health Conditions, Suicide Up After Major Trauma

Mental Health Conditions, Suicide Up After Major Trauma

Rise seen in postinjury rate of mental health diagnoses; suicide rate higher than population average.

CDC Probe Continues as Cases of Acute Flaccid Myelitis Rise

CDC Probe Continues as Cases of Acute Flaccid Myelitis Rise

252 patients currently under investigation for AFM, an increase of 33 patients since last week.

Critical Illness and the Brain: Managing Risk for Cognitive Adverse Effects

Critical Illness and the Brain: Managing Risk for Cognitive Adverse Effects

The results highlight the importance of evaluating and monitoring cognitive function in individuals with recent critical illness or major infections, especially if they are already at risk for dementia.

Concussion or mild traumatic brain injury linked with increased risk of suicide

In this systematic review and meta-analysis, history of concussion or mild traumatic brain injury was associated with a two-fold increased risk of suicide.

New Diagnostic Criteria for Neurosarcoidosis: What You Need to Know

New Diagnostic Criteria for Neurosarcoidosis: What You Need to Know

The new guidelines will facilitate the design and development of clinical trials to test new therapies to minimize the burden of neurologic disability produced by neurosarcoidosis.

Repetitive Hits May Predispose Athletes to Concussion

Repetitive Hits May Predispose Athletes to Concussion

Among college football players, number, severity of head impacts may affect risk for concussion.

Concussion-Related Biomarkers Vary Based on Sex, Race

Concussion-Related Biomarkers Vary Based on Sex, Race

Level of S100B up after sports-related concussion, especially within 4 hours of concussion.

Type 2 Diabetes May Have Adverse Effect on Parkinson Disease Symptoms, Outcomes

Type 2 Diabetes May Have Adverse Effect on Parkinson Disease Symptoms, Outcomes

Patients with both Parkinson disease and type 2 diabetes were more likely to have cardiovascular comorbidities than those with only Parkinson disease.

Alzheimer Disease Biomarkers Expose Individuals to Long-Term Care Insurance Denial

Alzheimer Disease Biomarkers Expose Individuals to Long-Term Care Insurance Denial

Approximately 5.5 million Americans have Alzheimer disease or dementia.

Biomarkers of Alzheimer Disease Observed in Down Syndrome

Biomarkers of Alzheimer Disease Observed in Down Syndrome

Neurological and neuropsychological examinations were performed to assess intellectual disabilities, and biological assays were performed on collected CSF and plasma.

Ivy League Rule Change Linked to Fewer Concussions During NCAA Football Games

Ivy League Rule Change Linked to Fewer Concussions During NCAA Football Games

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A 2016 experimental rule change in National Collegiate Athletic Association (NCAA) Division I Ivy League play has been linked to a reduction in concussions among players.

Multiple System Atrophy: A Common Form of Atypical Parkinsonism

Multiple System Atrophy: A Common Form of Atypical Parkinsonism

Multiple system atrophy is a rare, progressive neurodegenerative condition for which there is currently no cure.

Independent Links for Genetics, Lifestyle With Incident Stroke

Independent Links for Genetics, Lifestyle With Incident Stroke

Genetic and lifestyle factors are independently associated with incident stroke among men and women aged 40 to 73 years.

Half of Women Found to Develop Stroke, Dementia, or Parkinsonism

Half of Women Found to Develop Stroke, Dementia, or Parkinsonism

One in 2 women and 1 in 3 men will develop dementia, stroke, or parkinsonism during their lifetime.

Treating Chronic Itch: Therapeutic Review

Treating Chronic Itch: Therapeutic Review

Itch is "learned" in the nervous system, said Dr Berger, with involvement by both central and peripheral neural processes.

Exercise May Delay Symptoms of Alzheimer's in Those at Risk

Exercise May Delay Symptoms of Alzheimer's in Those at Risk

Findings among individuals with a genetic mutation known to cause Alzheimer's.

Change in Dietary Patterns Over 5 Years in Early Multiple Sclerosis

Change in Dietary Patterns Over 5 Years in Early Multiple Sclerosis

Researchers analyze the dietary habits of 260 patients in the early stages of multiple sclerosis from baseline to 5 years after initial onset of symptoms.

Hospitals Using Get With the Guidelines-Stroke Program Offer Better Quality Care in Ischemic Stroke

Hospitals Using Get With the Guidelines-Stroke Program Offer Better Quality Care in Ischemic Stroke

The Get With the Guidelines-Stroke program includes measures such as neurologist assessment, rehabilitation evaluation, and education on stroke risk factors.

Acetaminophen Can Reduce Recurrence of Febrile Seizures

Acetaminophen Can Reduce Recurrence of Febrile Seizures

For children, infants with febrile seizure, recurrence down with acetaminophen vs no antipyretic.

New AAN Guidelines for the Management of Disorders of Consciousness

New AAN Guidelines for the Management of Disorders of Consciousness

The new guidelines place a substantial emphasis on the importance of introducing high-quality rehabilitation early in these patients.

Fycompa Approved for Younger Epilepsy Patients With Partial-Onset Seizures

Fycompa Approved for Younger Epilepsy Patients With Partial-Onset Seizures

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Safety data for Fycompa was consistent with the safety profile in adult populations without the need for weight-based dosing.

NDA Submitted for Valtoco Nasal Spray to Treat Acute Repetitive Seizures

NDA Submitted for Valtoco Nasal Spray to Treat Acute Repetitive Seizures

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The Company states that the NDA is supported by robust clinical trial data, including patients studies where more than 1600 seizures were treated with Valtoco nasal spray.

Outcomes After Seizure Recurrence Upon AED Withdrawal Following Temporal Lobectomy

Outcomes After Seizure Recurrence Upon AED Withdrawal Following Temporal Lobectomy

Recurrence of seizures was reported in 28.2% of patients who attempted withdrawal.

Late-Onset Epilepsy Linked to <i>APOE</i> ε4, Smoking, Diabetes

Late-Onset Epilepsy Linked to APOE ε4, Smoking, Diabetes

The risk for late-onset epilepsy was lower in patients with higher physical activity levels and moderate alcohol intake.

Folic Acid Supplementation May Protect Against Language Delay in AED-Exposed Children

Folic Acid Supplementation May Protect Against Language Delay in AED-Exposed Children

The odds of language delay were lower at 18 months and 36 months in children exposed to AEDs in utero whose mothers took folic acid.

Effects of Parental Decision Aids on ED CT Rates Among Children at Risk for TBI

Effects of Parental Decision Aids on ED CT Rates Among Children at Risk for TBI

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Emergency department computed tomography rates for children with minor head trauma were not affected by parent decision aid use.

Case Study: Worsening Headache After Giving Birth

Case Study: Worsening Headache After Giving Birth

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A 32-year-old woman presents to the emergency department with gradually worsening generalized headache 8 days after giving birth to her second child.

Recreational Screen Time, Sleep Duration Linked to Cognitive Development in Children

Recreational Screen Time, Sleep Duration Linked to Cognitive Development in Children

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More than 2 hours of recreational screen time was found to be associated with cognitive decline in children.

Prevalence of Alzheimer's, Related Dementia Set to Double

Prevalence of Alzheimer's, Related Dementia Set to Double

Alzheimer's disease and related dementias burden is expected to increase to 3.3% in 2060.

Smoking Promotes Disease Progression in Multiple Sclerosis

Smoking Promotes Disease Progression in Multiple Sclerosis

Investigators examined the effects of smoking on respiratory symptoms and functional levels in patients with multiple sclerosis.

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