Neurology

Brivaracetam Effective for Reducing Seizures in Patients with Epileptic Encephalopathies

Brivaracetam Effective for Reducing Seizures in Patients with Epileptic Encephalopathies

Although 2 patients experienced an increase in seizure frequency, the remaining patients did not experience a change in frequency.

Many RA Patients' Pain Related to Central Nervous System

Many RA Patients' Pain Related to Central Nervous System

MRIs show rheumatoid arthritis patients have neurobiologic features observed in fibromyalgia.

New Guideline for Pediatric Mild Traumatic Brain Injury Diagnosis, Management

New Guideline for Pediatric Mild Traumatic Brain Injury Diagnosis, Management

Gradually increasing academic pursuits requires careful planning among the medical, school, and family units to enable prompt return and avoidance of prolonging school absence.

X-Rays, Blood Tests Not Advised for Children's Concussions

X-Rays, Blood Tests Not Advised for Children's Concussions

CT scans may be warranted in the case of vomiting, unconsciousness, and severe, worsening headaches.

Last 20 Years Saw Increase in Prevalence of ADHD in Children

Last 20 Years Saw Increase in Prevalence of ADHD in Children

Significant increases in prevalence in subgroups by age, sex, race/ethnicity, income, geographic region.

In Stroke Survivors, Cost-Related Non-Adherence Down After ACA

In Stroke Survivors, Cost-Related Non-Adherence Down After ACA

Among adult survivors of stroke, Medicaid increased, non-adherence decreased after ACA implementation.

Raising Awareness of Pseudobulbar Affect: Knowing the Signs, Symptoms, and Treatment for Patients With Uncontrollable Laughing or Crying

Raising Awareness of Pseudobulbar Affect: Knowing the Signs, Symptoms, and Treatment for Patients With Uncontrollable Laughing or Crying

Pseudobulbar affect is a significant national health issue in the United States, with approximately 2 million individuals affected.

Sensor Array May Detect De Novo Parkinson Disease in Breath

Sensor Array May Detect De Novo Parkinson Disease in Breath

Sensitivity, specificity, accuracy values of 79, 84, and 81% for detecting PD from controls.

Treatment of New-Onset Epilepsy: AAN, AES Update Practice Guidelines

Treatment of New-Onset Epilepsy: AAN, AES Update Practice Guidelines

An expert subcommittee was formed consisting of members of the AAN and AES to update the 2004 evidence-based guidelines on epilepsy treatment with AEDs.

TBI Linked to Increased Suicide Risk

TBI Linked to Increased Suicide Risk

Increased suicide risk with one, two, and three or more medical contacts for traumatic brain injury.

Traumatic brain injury associated with higher rate of suicide

In this retrospective study, Traumatic Brain Injury (TBI) was associated with a doubling in deaths by suicide, especially within the 6 months post-TBI.

Both Abstinence and High Alcohol Use Linked to Dementia

Both Abstinence and High Alcohol Use Linked to Dementia

Increased dementia risk for those with abstinence or with drinking 14 units alcohol/week in midlife.

Cognitive Impairment Profiles Differ Between Parkinson's, Alzheimer's

Cognitive Impairment Profiles Differ Between Parkinson's, Alzheimer's

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As the neurodegenerative processes of Alzheimer disease and Parkinson disease are different, early cognitive impairment also present differently in these diseases.

New Clinical Guideline for Evaluating Alzheimer's, Related Dementias

New Clinical Guideline for Evaluating Alzheimer's, Related Dementias

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Currently, there are no US consensus on best clinical practice guidelines that incorporate multispecialty recommendations for evaluating cognitive impairment that are thought to be due to Alzheimer's disease and Related Dementias (ADRD) for use by physicians and nurse practitioners.

Visual Function Deficits Up in Developmental Dyslexia

Visual Function Deficits Up in Developmental Dyslexia

Increased prevalence of deficits in visual function vs typically developing school-age children.

Cardiac Pathology in SUDEP Compared With Sudden Arrhythmic or Traumatic Deaths

Cardiac Pathology in SUDEP Compared With Sudden Arrhythmic or Traumatic Deaths

Causes of death in patients with epilepsy were assessed to determine the presence of cardiac pathology.

Overuse of Neuroimaging in the Emergency Department Reported for Pediatric Headache

Overuse of Neuroimaging in the Emergency Department Reported for Pediatric Headache

Investigators examined rates, predictors, and outcomes of neuroimaging in pediatric and adolescent patients who presented to the ED with a headache.

Retinal Nerve Fiber Layer Thickness May Be Associated With Cognitive Function

Retinal Nerve Fiber Layer Thickness May Be Associated With Cognitive Function

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Thinning of the retinal nerve fiber layer has been linked to worsening cognitive function and may be valuable in identifying individuals who may be at risk for cognitive decline.

Menopause Transition Often Prompts Changes in Migraine Pattern, Characteristics

Menopause Transition Often Prompts Changes in Migraine Pattern, Characteristics

This retrospective study sought to assess migraine patterns in 69 menopausal women between ages 40 and 60 who were treated at Partners Healthcare Hospitals for concurrent migraine headache.

Weighing the Risks of Deep Brain Stimulation

Weighing the Risks of Deep Brain Stimulation

DBS has been known to generate other movement-related disorders such as dyskinesias, blepharospasm, and hypokinesia.

Menopausal Hormone Therapy Slows Cognitive Decline in Postmenopausal Women

Menopausal Hormone Therapy Slows Cognitive Decline in Postmenopausal Women

Hormone therapy in postmenopausal women with mild cognitive impairment was examined.

First Marijuana-Based Drug Approved to Treat LGS, Dravet Syndrome

First Marijuana-Based Drug Approved to Treat LGS, Dravet Syndrome

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This marks the first approved drug that contains an active ingredient derived from marijuana as well as the first treatment approved for patients with Dravet syndrome.

NEURO Study: Neonatal neuroimaging with strong negative predictive value for developmental outcomes

In multivariate analyses, adverse late cranial ultrasound findings were an independent risk factor for full scale IQ scores 70.

Prenatal antidepressant exposure may increase risk of poor motor development

A meta-analysis of 18 studies examining the association of prenatal antidepressant exposure with motor development in children showed a small overall effect of worse motor development outcomes among children exposed to antidepressants in pregnancy.

Hearing Loss Linked to CVD Risks in Elderly

Hearing Loss Linked to CVD Risks in Elderly

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Elderly patients aged 80 years and older have an increased risk of developing cardiovascular disease (CVD) with worse hearing as well as hearing deterioration.

Higher Blood Pressure at Mid-Life Increases Dementia Risk

Higher Blood Pressure at Mid-Life Increases Dementia Risk

Findings for those with systolic BP 130 mm Hg at age 50 years

Genetic Risk Score Better Than APOE Alone for Assessing Risk for Alzheimer's Dementia

Genetic Risk Score Better Than APOE Alone for Assessing Risk for Alzheimer's Dementia

The genetic risk score primarily modified the risk for and onset of dementia and AD among homozygous carriers for APOE ε4.

Dementia, Alzheimer Disease Risk Increased With Lower Branched-Chain Amino Acid Levels

Dementia, Alzheimer Disease Risk Increased With Lower Branched-Chain Amino Acid Levels

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Lower BCAA levels may be associated with an increased risk of incident dementia.

Child Neuroblastoma Survivors at Risk for Psychological Impairment

Child Neuroblastoma Survivors at Risk for Psychological Impairment

Psychological impairment seen particularly in those with chronic health conditions

Excessive Daytime Sleepiness Linked to Elevated β-Amyloid Accumulation in Elderly Persons

Excessive Daytime Sleepiness Linked to Elevated β-Amyloid Accumulation in Elderly Persons

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Elderly individuals without dementia who have elevated daytime sleepiness may be at greater risk for β-amyloid accumulation.

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