Ob/Gyn Information Center News Archive
The USPSTF recommends risk-reducing medications for women at high risk for breast cancer who are at low risk for adverse events, but medications are not recommended for routine use.
Eliminating routine oral opioid prescription following cesarean delivery may reduce opioid consumption without jeopardizing pain control or patient satisfaction.
Increased risk for new-onset, postpartum mental illness observed in patients with inflammatory bowel disease.
Pregnant women admitted to ICU with flu more likely to deliver preterm infants, low birth-weight infants.
The need for effective osteoporosis screening tools and treatment strategies is high, as the current methods have a low sensitivity for determining postmenopausal women at risk for a major osteoporotic fracture.
A psychoeducational intervention does not improve anxiety or body image but is still considered important among women with breast cancer.
A study was conducted to assess the safety, tolerability, and efficacy of methyl estradiolpropanoate, a topical soft estrogen cosmeceutical for the treatment of estrogen-deficient skin.
Pregnant women presenting with migraine to acute care settings were found to be treated with therapeutic agents ranging from safe and effective medications to others with unclear efficacy and potential teratogenicity.
Researchers sought to determine if the complementary practice could prevent CIPN in patients receiving adjuvant chemotherapy for breast cancer.
Female sterilization is most commonly used method, followed by oral contraceptive pill.
Women who used a self-screening assay for high-risk human papillomavirus had similar test results to those who were screened by a clinician.
New research may help identify new candidate targets and stratify patients eligible for innovative therapies.
Black women with the most common type of breast cancer had worse clinical outcomes compared with white women, despite receiving similar systemic therapy.
Elective cesarean delivery may influence the risk of early childhood overweight.
Researchers find that surgical decision making is often driven by factors beyond extent of disease.
Pilot study sought to determine risk of breast cancer among African American women veterans.
Researchers sought to determine how subjective measures of CIPN correlated with objective measures of CIPN.
Study findings measure quality of life for pregnant patients with breast cancer and reveals the effectiveness of disease-specific assessment tools.
A levonorgestrel 52-mg intrauterine system was found to be safe and effective for pregnancy prevention.
Findings observed in early-stage breast cancer survivors followed for up to 6 years after treatment.
Placental malaria has a profound effect on the fetal immune system, and prenatal malaria exposure categories may drive heterogeneity to malaria susceptibility.
After childbirth, the risk for pelvic floor disorders varies by delivery mode.
For postmenopausal women, vaginal estrogen use is not associated with negative health outcomes.
No evidence for reduction in risk for late miscarriage or spontaneous preterm birth as a result of screening and treatment for bacterial vaginosis.
Internationally, infertility is ranked as the fifth most serious disability among women.
Guidelines include use of lowest effective dose, smallest quantity of opioids needed for expected pain.
Women with 5 or more live births at increased risk for coronary heart disease, hospitalized MI.
Small number of reports include infections, vaginal irritation, localized vaginal injury.
Postmenopausal women with normal BMI and elevated body fat levels are at increased risk of breast cancer.
Oxybutynin, an anticholinergic used to treat urinary incontinence, may provide breast cancer survivors with an alternative treatment option for hot flashes, according to new research.
Women born during the Chinese famine period may be at increased risk for early natural menopause and premature ovarian failure.
Is there an association between breast cancer risk and recent childbirth?
A pair of new case-finding strategies may help general practitioners identify and refer patients and survivors of ovarian cancer to genetic counseling and DNA testing.
Overall, 49% of pregnant women with syphilis did not report any of 15 risk factors.
The first successful case of a live birth following uterine transplantation from a deceased donor was reported at the São Paulo School of Medicine, Brazil.
UROPP reduces opioids prescribed after gynecologic, abdominal surgery without negative effects.
Providers believe stressing fetal protection is most effective strategy against refusal.
The study utilized the Vaccine Safety Datalink and included children who received the first dose of a measles-containing vaccine between 12 and 23 months old during the study period of January 1, 2003 to September 20, 2015.
To investigate the association between hormone therapy and carpal tunnel syndrome risk, researchers conducted a secondary analysis of the Women's Health Initiative (WHI) hormone therapy trials.
Endometriosis is most common cause of secondary dysmenorrhea, looks different in teens than adults.
Women who undergo surgical menopause have significantly worse sleep quality than those who experience natural menopause.
History of sexual assault and current PTSD also associated with higher risk for menopause symptoms.
Increase in amphetamine-, opioid-related deliveries disproportionate between rural vs. urban counties.
Severity of symptoms of vulvovaginal atrophy in postmenopausal women was found to have an impact on quality of life.
Early screening may benefit those with dense breasts, personal/family history of breast cancer.
No statistically significant differences in prevalence rates seen between boys and girls.
Between 2007 and 2016, pregnancy-associated mortality related to opioids more than doubled.
A diet high in fruits, vegetables, nuts, and legumes was found to be associated with a lower risk for physical, mental, and genitourinary symptoms of menopause compared with a diet high in fats, meats, desserts, and salts.
State-level reforms and improvements in healthcare practices and institutional attitudes are necessary to improve maternal mortality rates.
Cancer detection rate is 8.4/1000 exams in older women; 98% of cancers surgically excised.
Progesterone receptor levels as a biomarker may improve predictability of response to progestin-based therapy for endometriosis.
Early age of menopause development is associated with lower overall life expectancy and fewer years of life without diabetes.
Functional disability progressed more rapidly in postmenopausal compared with premenopausal women with rheumatoid arthritis.
Six-month interval associated with greater risk than 18-month interval for women of any age.
Treatment with oral clindamycin for pregnant women with bacterial vaginosis in their first trimester does not reduce the risk of late miscarriage or very preterm delivery.
Researchers at the National Institute of Environmental Health Sciences (NIEHS), Vanderbilt University Medical Center, and the Henry Ford Health System analyzed patient data from African-American women aged 23 to 35 years (N=1553) who were participating in the NIEHS Study of Environment, Lifestyle, and Fibroids (SELF).
Nine in 10 women experience multiple symptoms prediagnosis; 8 in 10 of them consult a doctor.
A birth control coverage opt-out for employers was finalized by the Trump administration on Wednesday.
Nearly half of women older than 50 years report having urinary incontinence.
Tissue-Selective Estrogen Complex May Benefit Postmenopausal Women With Vaginal Bleeding, Breast Discomfort
Switching to tissue-selective estrogen complex from hormone therapy may benefit women with breast discomfort or vaginal bleeding.
One-view digital breast tomosynthesis with a reduced compression force detected breast cancer with higher sensitivity and lower specificity than 2-view digital mammography.
Influenza Vaccines May Protect Against Lab-Confirmed Influenza-Linked Hospitalization During Pregnancy
For women who are pregnant, influenza vaccines may moderately protect against laboratory-confirmed influenza-associated hospitalization.
Based on data from 40 jurisdictions, increase from 5.2 to 5.6% in GDM from 2012 to 2016.
The US Preventive Services Task Force (USPSTF) has concluded that current evidence is insufficient for assessing the balance of harms and benefits of screening for elevated blood lead levels in asymptomatic children and pregnant women.
The risk for breast cancer recurrence can be extracted using disease-specific survival data.
The number of cesarean deliveries has nearly doubled from 2000 to 2015, with overuse occurring most frequently in middle- and high-income countries.
Prenatal exposure to phthalates is associated with language delay in children.
Researchers developed a 4-phase life stress interview to determine whether women with chronic urogenital pain could derive benefits from disclosing stressors and gaining awareness of links between stress, emotions, and symptoms.
Women in states with paid family leave policies have a modestly greater likelihood of exclusively breastfeeding at 6 months.
Approval from the Food and Drug Administration (FDA) was supported by the Phase 3 Replenish trial which evaluated the safety and efficacy of Bijuva in generally healthy, postmenopausal women with a uterus for the treatment of moderate to severe hot flashes.
Higher levels of estradiol were inversely associated with carotid artery intima-media thickness progression in the early postmenopausal cohort but positively associated with it in the late postmenopausal group.
Rates of preterm birth, low-birth weight lower among low-income women.
Preeclampsia seems to be associated with an increased risk for dementia, especially vascular dementia, with a stronger correlation for late-onset disease.
Treatment with chemotherapeutics promoted atrophy and mitochondrial damage in breast muscle cells.
Reduced head circumference in the offspring of women with untreated bipolar disorder appeared to be related to sociodemographic characteristics.
For patients with metastatic triple-negative breast cancer, atezolizumab plus nanoparticle albumin-bound-paclitaxel prolongs progression-free survival compared with placebo plus nab-paclitaxel.
Third Trimester Immunization With Tdap Vaccine Optimal for Pertussis Toxin Antibody Concentrations in Newborns
Immunization with Tdap vaccine during the third trimester of pregnancy resulted in higher concentrations of pertussis toxin antibodies in newborns.
Talzenna, a poly (ADP-ribose) polymerase (PARP) inhibitor, was evaluated in EMBRACA, an open-label trial that randomized patients with gBRCAm HER2-negative locally advanced or metastatic breast cancer (N=431) to receive talazoparib 1mg or physician's choice of chemotherapy (capecitabine, eribulin, gemcitabine, or vinorelbine).
The expanded approval was supposed by safety and efficacy data from the Phase 3 ACCESS IUS trial (N=1751) in women receiving Liletta. In the trial, Liletta demonstrated >99% efficacy in preventing pregnancy for up to 5 years in a broad patient population.
Postmenopausal women with weight loss have a reduced risk for breast cancer.
The use of β-blockers in the first trimester of pregnancy may not greatly increase the risk for major congenital malformations in offspring.
Higher risk for problems seen among black women, women with other health conditions.
Rate of spontaneous vaginal delivery similar for immediate pushing or waiting for 60 minutes.
One of the goals of the US Department of Health and Human Services National Viral Hepatitis Action Plan is to eliminate mother-to-infant transmission of HCV infection.
82 percent of variant carriers identified in exome sequencing had not undergone prior testing.
Monovalent Acellular Pertussis Vaccine Safe and Effective for Neonates With Mothers Unvaccinated for Tdap
The monovalent acellular pertussis vaccine may be beneficial to neonates whose mothers did not receive Tdap vaccine during pregnancy.
Hypertensive disorders of pregnancy and gestational diabetes may increase the risk for hot flashes during menopause.
Patients undergoing robotic hysterectomy were found to report comparable pain scores when receiving celecoxib perioperatively or ketorolac postoperatively.
Almost 43% of those presenting to NCI center for second opinion have change in diagnosis.
Use of ondansetron for the treatment of nausea and vomiting in pregnancy does not appear to be associated with birth defects.
Light treatments successfully corrected abnormal timing of melatonin circadian rhythms in perimenopausal women with depression and improved mood and sleep within 2 weeks.
The recent Supreme Court decision on crisis pregnancy centers is expected to complicate the future of some health laws.
Talazoparib, a poly(adenosine diphosphate-ribose) inhibitor, may significantly enhance progression-free survival in patients with advanced breast cancer and a germline BRCA1/2 mutation.
These findings suggest an increased risk for postpartum depressive symptoms in mothers with gestational diabetes, independent of depressive symptomatology during pregnancy.
Combined hormonal contraception use tied to lower risk; risk down with increasing duration of use.
"Moral norms" in the medical domain must be applied to pregnant women and their physicians.
This research rejects any association between increased risk for ADHD and changes in children's microbiota related to cesarean delivery or antibiotic use.
The FDA based its approval on the results of a triplet of phase 3 studies, the MONALEESA-2, MONALEESA-3, and MONALEESA-7.
Recommendations developed to support pediatric providers in managing patients with FASD diagnosis.
For this phase 1b study, researchers enrolled 57 patients with ERBB2/HER2-positive metastatic breast cancer previously treated with trastuzumab and a taxane.