Ob/Gyn Information Center News Archive

USPSTF Recommends Risk-Reducing Meds for Breast Cancer

The USPSTF recommends risk-reducing medications for women at high risk for breast cancer who are at low risk for adverse events, but medications are not recommended for routine use.

Pain Management Following Reduced Routine Opioid Use After Cesarean Delivery

Eliminating routine oral opioid prescription following cesarean delivery may reduce opioid consumption without jeopardizing pain control or patient satisfaction.

Postpartum New-Onset Mental Illness Risk Up With IBD

Increased risk for new-onset, postpartum mental illness observed in patients with inflammatory bowel disease.

Adverse Birth Outcomes Up for Women With H1N1 Flu in ICU

Pregnant women admitted to ICU with flu more likely to deliver preterm infants, low birth-weight infants.

Comparing Osteoporosis Screening, Treatment Strategies in Postmenopausal Women

The need for effective osteoporosis screening tools and treatment strategies is high, as the current methods have a low sensitivity for determining postmenopausal women at risk for a major osteoporotic fracture.

Psychoeducational Intervention of Little Benefit in Breast Cancer

A psychoeducational intervention does not improve anxiety or body image but is still considered important among women with breast cancer.

Topical Methyl Estradiolpropanoate Safe, Effective for Treating Estrogen-Deficient Skin

A study was conducted to assess the safety, tolerability, and efficacy of methyl estradiolpropanoate, a topical soft estrogen cosmeceutical for the treatment of estrogen-deficient skin.

Treating Acute Migraine During Pregnancy: The Need for Guidelines

Pregnant women presenting with migraine to acute care settings were found to be treated with therapeutic agents ranging from safe and effective medications to others with unclear efficacy and potential teratogenicity.

Classical Massage Mitigates CIPN Due to Adjuvant Chemotherapy for Breast Cancer

Researchers sought to determine if the complementary practice could prevent CIPN in patients receiving adjuvant chemotherapy for breast cancer.

CDC: 65% of US Women Currently Using Contraceptives

Female sterilization is most commonly used method, followed by oral contraceptive pill.

Self-Sampling Strategy to Encourage Screening for High-Risk Human Papillomavirus

Women who used a self-screening assay for high-risk human papillomavirus had similar test results to those who were screened by a clinician.

Mutations Identified Distinguishing Metastatic from Early-Stage HR+/HER2- Breast Cancer

New research may help identify new candidate targets and stratify patients eligible for innovative therapies.

TAILORx Shows Black Women With Breast Cancer Have Worse Clinical Outcomes

Black women with the most common type of breast cancer had worse clinical outcomes compared with white women, despite receiving similar systemic therapy.

Cesarean Delivery Outcomes May Influence Risk for Early Childhood Overweight

Elective cesarean delivery may influence the risk of early childhood overweight.

Despite Breast-Conserving Surgery Eligibility, Nearly 50% of Women Chose Mastectomy

Researchers find that surgical decision making is often driven by factors beyond extent of disease.

Risk of Breast Cancer Higher for African American Female Veterans

Pilot study sought to determine risk of breast cancer among African American women veterans.

CIPN in Breast Cancer: Do Subjective and Objective Measures Correlate?

Researchers sought to determine how subjective measures of CIPN correlated with objective measures of CIPN.

Quality of Life Decreased in Women With Breast Cancer During or Shortly After Pregnancy

Study findings measure quality of life for pregnant patients with breast cancer and reveals the effectiveness of disease-specific assessment tools.

Study Finds Intrauterine Levonorgestrel Contraceptive System Safe, Effective

A levonorgestrel 52-mg intrauterine system was found to be safe and effective for pregnancy prevention.

Endocrine Treatment Does Not Impair Neuropsychological Performance

Findings observed in early-stage breast cancer survivors followed for up to 6 years after treatment.

Prenatal Malaria Exposure Modulates Innate Immune Responses at Birth

Placental malaria has a profound effect on the fetal immune system, and prenatal malaria exposure categories may drive heterogeneity to malaria susceptibility.

Delivery Mode Tied to Pelvic Floor Disorder Risk After Childbirth

After childbirth, the risk for pelvic floor disorders varies by delivery mode.

Postmenopausal Vaginal Estrogen Not Associated With Negative Health Outcomes

For postmenopausal women, vaginal estrogen use is not associated with negative health outcomes.

Bacterial Vaginosis Treatment Does Not Reduce Late Miscarriages, Preterm Birth

No evidence for reduction in risk for late miscarriage or spontaneous preterm birth as a result of screening and treatment for bacterial vaginosis.

Assessing Inequalities in Infertility Care Among Women

Internationally, infertility is ranked as the fifth most serious disability among women.

Guidelines Developed for Opioid Use in Vaginal Birth

Guidelines include use of lowest effective dose, smallest quantity of opioids needed for expected pain.

Pregnancy Losses Linked to Risk for Cardiovascular Disease

Women with 5 or more live births at increased risk for coronary heart disease, hospitalized MI.

Recalled Kotex Tampons Can Unravel Inside Body

Small number of reports include infections, vaginal irritation, localized vaginal injury.

Postmenopausal Women With Normal BMI May Still Be at Increased Risk for Breast Cancer

Postmenopausal women with normal BMI and elevated body fat levels are at increased risk of breast cancer.

Urinary Incontinence Drug May Reduce Frequency of Hot Flashes

Oxybutynin, an anticholinergic used to treat urinary incontinence, may provide breast cancer survivors with an alternative treatment option for hot flashes, according to new research.

Food Deprivation During Fetal Development Linked to Early Menopause, Premature Ovarian Failure

Women born during the Chinese famine period may be at increased risk for early natural menopause and premature ovarian failure.

Increased Breast Cancer Risk After Childbirth May Last Decades

Is there an association between breast cancer risk and recent childbirth?

Primary Care May Aid Genetic Counseling Referral for Ovarian Cancer Survivors

A pair of new case-finding strategies may help general practitioners identify and refer patients and survivors of ovarian cancer to genetic counseling and DNA testing.

2012 to 2016 Saw Increase in Syphilis Among Pregnant Women

Overall, 49% of pregnant women with syphilis did not report any of 15 risk factors.

Uterine Transplant From Deceased Donor Results in Successful Childbirth

The first successful case of a live birth following uterine transplantation from a deceased donor was reported at the São Paulo School of Medicine, Brazil.

Ultrarestrictive Opioid Presciption Protocol Cuts Postoperative Opioid Use

UROPP reduces opioids prescribed after gynecologic, abdominal surgery without negative effects.

Pregnant Women Commonly Refuse Vaccines

Providers believe stressing fetal protection is most effective strategy against refusal.

Does Gestational Age at Birth Impact Seizure Risk Following Receipt of Measles Vaccine?

The study utilized the Vaccine Safety Datalink and included children who received the first dose of a measles-containing vaccine between 12 and 23 months old during the study period of January 1, 2003 to September 20, 2015.

Menopausal Hormone Therapy May Reduce Carpal Tunnel Syndrome Risk

To investigate the association between hormone therapy and carpal tunnel syndrome risk, researchers conducted a secondary analysis of the Women's Health Initiative (WHI) hormone therapy trials.

New Guidance Addresses Early Diagnosis of Dysmenorrhea in Adolescents

Endometriosis is most common cause of secondary dysmenorrhea, looks different in teens than adults.

Sleep Quality in Women With Surgical vs Natural Menopause

Women who undergo surgical menopause have significantly worse sleep quality than those who experience natural menopause.

History of Partner Violence Tied to Menopause Symptoms

History of sexual assault and current PTSD also associated with higher risk for menopause symptoms.

Increase Seen in Amphetamine, Opioid Use in Pregnant Women

Increase in amphetamine-, opioid-related deliveries disproportionate between rural vs. urban counties.

Severe Symptoms of Vulvovaginal Atrophy Associated With Reduced Quality of Life

Severity of symptoms of vulvovaginal atrophy in postmenopausal women was found to have an impact on quality of life.

RSNA: Mammography May Benefit 30-Year-Olds With Risk Factors

Early screening may benefit those with dense breasts, personal/family history of breast cancer.

Prevalence of Eating Disorders 1.4% in Preteens

No statistically significant differences in prevalence rates seen between boys and girls.

Pregnancy-Associated Mortality Involving Opioids Up

Between 2007 and 2016, pregnancy-associated mortality related to opioids more than doubled.

Healthy Diet Associated With Reduced Menopausal Symptoms

A diet high in fruits, vegetables, nuts, and legumes was found to be associated with a lower risk for physical, mental, and genitourinary symptoms of menopause compared with a diet high in fats, meats, desserts, and salts.

Examining Racial Disparities in US Maternal Mortality

State-level reforms and improvements in healthcare practices and institutional attitudes are necessary to improve maternal mortality rates.

RSNA: Mammography Has Value in Women Age 75 or Older

Cancer detection rate is 8.4/1000 exams in older women; 98% of cancers surgically excised.

Progesterone Receptor Status May Aid Progestin-Based Endometriosis Therapy

Progesterone receptor levels as a biomarker may improve predictability of response to progestin-based therapy for endometriosis.

Early Menopause Associated With Shorter Life Expectancy, Early Diagnosis of Type 2 Diabetes

Early age of menopause development is associated with lower overall life expectancy and fewer years of life without diabetes.

Functional Disability Progression More Rapid in Postmenopausal Women With RA

Functional disability progressed more rapidly in postmenopausal compared with premenopausal women with rheumatoid arthritis.

Short Interpregnancy Intervals Tied to Adverse Outcome Risk

Six-month interval associated with greater risk than 18-month interval for women of any age.

Assessment of Bacterial Vaginosis Screening, Treatment for Prevention of Preterm Delivery

Treatment with oral clindamycin for pregnant women with bacterial vaginosis in their first trimester does not reduce the risk of late miscarriage or very preterm delivery.

Women Fed Soy Formula as Infants More Likely to Experience Menstrual Pain

Researchers at the National Institute of Environmental Health Sciences (NIEHS), Vanderbilt University Medical Center, and the Henry Ford Health System analyzed patient data from African-American women aged 23 to 35 years (N=1553) who were participating in the NIEHS Study of Environment, Lifestyle, and Fibroids (SELF).

Many Women Have Not Heard of Ovarian Cancer Before Diagnosis

Nine in 10 women experience multiple symptoms prediagnosis; 8 in 10 of them consult a doctor.

Trump Administration Finalizes Birth Control Coverage Opt-Out

A birth control coverage opt-out for employers was finalized by the Trump administration on Wednesday.

Urinary Incontinence Common in Women Over 50 Years

Nearly half of women older than 50 years report having urinary incontinence.

Tissue-Selective Estrogen Complex May Benefit Postmenopausal Women With Vaginal Bleeding, Breast Discomfort

Switching to tissue-selective estrogen complex from hormone therapy may benefit women with breast discomfort or vaginal bleeding.

Higher Sensitivity With 1-View Digital Breast Tomosynthesis for Breast Cancer Detection

One-view digital breast tomosynthesis with a reduced compression force detected breast cancer with higher sensitivity and lower specificity than 2-view digital mammography.

Influenza Vaccines May Protect Against Lab-Confirmed Influenza-Linked Hospitalization During Pregnancy

For women who are pregnant, influenza vaccines may moderately protect against laboratory-confirmed influenza-associated hospitalization.

CDC: Prevalence of Gestational Diabetes 6.0% in 2016

Based on data from 40 jurisdictions, increase from 5.2 to 5.6% in GDM from 2012 to 2016.

USPSTF: Evidence Lacking for Lead Screen in Kids, Pregnancy

The US Preventive Services Task Force (USPSTF) has concluded that current evidence is insufficient for assessing the balance of harms and benefits of screening for elevated blood lead levels in asymptomatic children and pregnant women.

New Method Estimates Risk for Recurrence in Breast Cancer

The risk for breast cancer recurrence can be extracted using disease-specific survival data.

Significant Increase Seen in Cesarean Deliveries Worldwide

The number of cesarean deliveries has nearly doubled from 2000 to 2015, with overuse occurring most frequently in middle- and high-income countries.

Prenatal Exposure to Phthalates Linked to Language Delay

Prenatal exposure to phthalates is associated with language delay in children.

Encouraging Emotional Awareness, Expression of Life Stress in Women With Chronic Urogenital Pain

Researchers developed a 4-phase life stress interview to determine whether women with chronic urogenital pain could derive benefits from disclosing stressors and gaining awareness of links between stress, emotions, and symptoms.

Paid Family Leave Policies May Modestly Increase Breastfeeding

Women in states with paid family leave policies have a modestly greater likelihood of exclusively breastfeeding at 6 months.

Bijuva Approved for Moderate to Severe Vasomotor Symptoms From Menopause

Approval from the Food and Drug Administration (FDA) was supported by the Phase 3 Replenish trial which evaluated the safety and efficacy of Bijuva in generally healthy, postmenopausal women with a uterus for the treatment of moderate to severe hot flashes.

Atherosclerosis Progression Differs According to Timing of Estradiol Therapy After Menopause

Higher levels of estradiol were inversely associated with carotid artery intima-media thickness progression in the early postmenopausal cohort but positively associated with it in the late postmenopausal group.

Midwifery Care Cuts Poor Birth Outcomes vs Physician Care

Rates of preterm birth, low-birth weight lower among low-income women.

Preeclampsia Tied to Increased Risk for Vascular Dementia

Preeclampsia seems to be associated with an increased risk for dementia, especially vascular dementia, with a stronger correlation for late-onset disease.

Chemotherapy Plays a Role in Skeletal Muscle Atrophy in Patients With Breast Cancer

Treatment with chemotherapeutics promoted atrophy and mitochondrial damage in breast muscle cells.

Psychotropic Medications May Improve Pregnancy Outcomes in Bipolar Disorder

Reduced head circumference in the offspring of women with untreated bipolar disorder appeared to be related to sociodemographic characteristics.

Chemoimmunotherapy Increases Survival in Triple-Negative Breast Cancer

For patients with metastatic triple-negative breast cancer, atezolizumab plus nanoparticle albumin-bound-paclitaxel prolongs progression-free survival compared with placebo plus nab-paclitaxel.

Third Trimester Immunization With Tdap Vaccine Optimal for Pertussis Toxin Antibody Concentrations in Newborns

Immunization with Tdap vaccine during the third trimester of pregnancy resulted in higher concentrations of pertussis toxin antibodies in newborns.

Talzenna Approved for Germline BRCA-Mutated, HER2-Negative Breast Cancer

Talzenna, a poly (ADP-ribose) polymerase (PARP) inhibitor, was evaluated in EMBRACA, an open-label trial that randomized patients with gBRCAm HER2-negative locally advanced or metastatic breast cancer (N=431) to receive talazoparib 1mg or physician's choice of chemotherapy (capecitabine, eribulin, gemcitabine, or vinorelbine).

Liletta Now Approved for Pregnancy Prevention for Up to 5 Years

The expanded approval was supposed by safety and efficacy data from the Phase 3 ACCESS IUS trial (N=1751) in women receiving Liletta. In the trial, Liletta demonstrated >99% efficacy in preventing pregnancy for up to 5 years in a broad patient population.

Weight Loss May Reduce Breast Cancer Risk in Postmenopausal Women

Postmenopausal women with weight loss have a reduced risk for breast cancer.

β-Blockers in Early Pregnancy Not Linked to Significant Risk for Overall, Cardiac Malformations

The use of β-blockers in the first trimester of pregnancy may not greatly increase the risk for major congenital malformations in offspring.

Minority Women at Higher Risk for Severe Maternal Morbidity

Higher risk for problems seen among black women, women with other health conditions.

Timing of Pushing Does Not Impact Spontaneous Vaginal Delivery

Rate of spontaneous vaginal delivery similar for immediate pushing or waiting for 60 minutes.

Need for Adequate Screening for Infants With HCV Infected Mothers During Pregnancy

One of the goals of the US Department of Health and Human Services National Viral Hepatitis Action Plan is to eliminate mother-to-infant transmission of HCV infection.

Genomic Screening Can ID Undetected BRCA1/2 Cancer Risk

82 percent of variant carriers identified in exome sequencing had not undergone prior testing.

Monovalent Acellular Pertussis Vaccine Safe and Effective for Neonates With Mothers Unvaccinated for Tdap

The monovalent acellular pertussis vaccine may be beneficial to neonates whose mothers did not receive Tdap vaccine during pregnancy.

Disorders in Pregnancy May Increase Risk for Hot Flashes During Menopause

Hypertensive disorders of pregnancy and gestational diabetes may increase the risk for hot flashes during menopause.

Celecoxib Offers Pain Relief Comparable to Ketorolac After Robotic Hysterectomy

Patients undergoing robotic hysterectomy were found to report comparable pain scores when receiving celecoxib perioperatively or ketorolac postoperatively.

Second Opinion at NCI Center Valuable for Breast CA Patients

Almost 43% of those presenting to NCI center for second opinion have change in diagnosis.

Ondansetron in Pregnancy Not Linked to Most Birth Defects

Use of ondansetron for the treatment of nausea and vomiting in pregnancy does not appear to be associated with birth defects.

Light Therapy Offers Nonpharmacologic Treatment for Perimenopausal Depression

Light treatments successfully corrected abnormal timing of melatonin circadian rhythms in perimenopausal women with depression and improved mood and sleep within 2 weeks.

Uncertain Future for Health Laws After Supreme Court Crisis Pregnancy Center Ruling

The recent Supreme Court decision on crisis pregnancy centers is expected to complicate the future of some health laws.

Talazoparib Shows Antitumor Activity in Advanced Breast Cancer, Germline BRCA Mutation

Talazoparib, a poly(adenosine diphosphate-ribose) inhibitor, may significantly enhance progression-free survival in patients with advanced breast cancer and a germline BRCA1/2 mutation.

Gestational Diabetes Associated With Increased Risk for Postpartum Depression

These findings suggest an increased risk for postpartum depressive symptoms in mothers with gestational diabetes, independent of depressive symptomatology during pregnancy.

Newer Hormonal Contraception May Cut Ovarian Cancer Risk

Combined hormonal contraception use tied to lower risk; risk down with increasing duration of use.

The Ethics of Forced Cesareans: An Unthinkable Practice, Examined

"Moral norms" in the medical domain must be applied to pregnant women and their physicians.

Cesarean Delivery, Early Childhood Antibiotic Use Not Associated With Risk for ADHD

This research rejects any association between increased risk for ADHD and changes in children's microbiota related to cesarean delivery or antibiotic use.

Ribociclib FDA-Approved For Additional Indications in HR+, HER2- Advanced Breast Cancer

The FDA based its approval on the results of a triplet of phase 3 studies, the MONALEESA-2, MONALEESA-3, and MONALEESA-7.

AAP Report Addresses Managing Fetal Alcohol Spectrum Disorder

Recommendations developed to support pediatric providers in managing patients with FASD diagnosis.

Tucatinib May Be A Safe, Novel Treatment for ERBB2/HER2-Positive Breast Cancer

For this phase 1b study, researchers enrolled 57 patients with ERBB2/HER2-positive metastatic breast cancer previously treated with trastuzumab and a taxane.

Sign Up for Free e-newsletters