Pain News Archive

Pain, Psychiatric Comorbidities More Common in Chronic vs Episodic Migraine

Individuals with chronic vs episodic migraine may be more likely to experience chronic back pain, chronic pain, neck pain, anxiety, and depression.

Synthetic Opioid Involvement in Opioid-Related Deaths Increases

From 2010 to 2016, synthetic opioid involvement up from 14.3 to 45.9% of opioid-related deaths

Intrathecal Drug Delivery and Spinal Cord Stimulation for Cancer Pain: A Review

Intrathecal drug delivery systems and spinal cord stimulation have shown promise for the treatment of cancer pain in initial studies.

Combining Spinal Manipulation and Exercise for Low Back Pain in Adolescents

A combination of self-care education, aerobic and strength-training exercise, and spinal manipulation therapy may provide greater pain relief and improved treatment satisfaction compared with exercise only in adolescents with low back pain.

People With Opioid Use Disorder Have High Suicide Rate

Based on data from multiple sources, many opioid-overdose deaths seem to be suicides

Intraoperative Opioid Doses and Rates of Hospital Readmission

The use of high doses of opioids — particularly long-acting opioids — during surgery may increase the risk for 30-day readmission.

Study Finds 31% Use No Opioids After Surgery

At discharge, 92.2% of patients received an opioid prescription; nearly 63% unused

Eight Factors Predict Pain After Spine Surgery

Post-op pain strongly linked to number of classes of non-opioid analgesics used, remifentanil use

Headache in Older Adults: Unique Causes and Treatments

It is important for clinicians to quickly and accurately determine potential underlying causes and to prescribe treatments that take into account comorbidities and medications that older patients may be taking for them.

Addition of Peripheral Nerve Blocks Beneficial for TKA

Lower numeric rating scale pain scores on ambulation on postoperative days zero, one, and two

Helping to End Addiction: NIH Initiative Addresses Opioid Epidemic

National Institutes of Health Director, Francis Collins, MD, PhD, announced on April 4, 2018 the launch of the Helping to End Addiction Long-Term Initiative.

Opiate Use Linked to Early Mortality in IBD Patients

Heavy use in Crohn's, heavy or moderate use in ulcerative colitis tied to increased risk of death

Elder Abuse Not Associated With Risk of Chronic Pain

Findings based on two-year follow-up of a large, community-dwelling cohort in Malaysia

CBT vs Pain Education for Chronic Pain in Low-Income Clinics

Group cognitive behavioral therapy and pain education may be more effective than usual care for improving pain and physical function in patients presenting with chronic pain at low-income clinics.

Tai Chi May Be Therapeutic Option for Fibromyalgia

Tai chi interventions may be more effective at treating fibromyalgia than aerobic exercise.

FDA: Social Media Companies Are Not Doing Enough to Stop Illegal Opioid Sales

FDA has called on social media companies and internet service providers to take a proactive approach in curbing online selling of opioids through their platforms.

Fatigue, muscle aches more common in women with HIV than men

The two most prevalent HIV symptoms, fatigue and muscle aches, are more common in women than men and can worsen with menopause.

CDC reports opioid-related overdoses have increased from July 2016 to Sept 2017

The rate of ER visits for suspected opioid-related overdoses has increased by a mean of 5.6% per quarter.

Gluten-free diet associated with reduced neuropathy pain

Individuals with gluten neuropathy experienced less peripheral neuropathic pain when adhering to strict gluten-free diets.

Transcutaneous electrical nerve stimulation may not alleviate lower back pain

Transcutaneous electrical nerve stimulation may be ineffective in treating, relieving lower back pain when compared with other nerve stimulation therapies.

Assessing lidocaine efficacy for chronic pain management

Intravenous, patch lidocaine might be effective in treating, preventing chronic pain.

Poor sleep exacerbates PTSD, chronic pain association in youth

The quality of sleep partly relieved the correlation between PSTD and pain intensity, interference.

Pain sensation may be altered by verum, sham electroacupuncture

Functional magnetic resonance imaging was used to monitor brain activity in patients with osteoarthritis who were administered either genuine or placebo electroacupuncture.

FDA: Botanical drug kratom contains opioid compounds

Nearly all of kratom's major compounds bind to opioid receptors in the human brain, and 2 of the top 5 most prevalent compounds activate those receptors, FDA Commissioner Scott Gottlieb said in a statement. In addition, there have been 44 reported deaths associated with the use of kratom, often in combination with other substances, Gottlieb said.

Brief intervention may be beneficial for adolescents with chronic pain

A combination of psychoeducation, cognitive-based therapy, visualization, and breathing exercises may represent a tolerable and readily accepted complementary therapeutic approach for adolescent patients with chronic pain.

Pain during IUD insertion reduced with lidocaine nerve block

A 1% paracervical nerve block may be useful for reducing patient-reported pain during IUD insertion.

Effects of cannabis treatment in adult patients with PTSD

Researchers found that cannabis may alleviate neuropathic pain, but is not associated with benefit for adults with PTSD.

Clinicians may be overprescribing gabapentinoids for pain

Gabapentinoids may be overprescribed, in part as a response to the opioid epidemic.

NASEM report outlines strategy to combat opioid epidemic

The FDA commissioned the report to provide an update on current evidence on research, care, and education in the pain field, and to identify actionable measures for the FDA to more adequately address the ongoing opioid epidemic.

CDC: Opioid prescription rate remains high, inconsistent in the United States

However, the number of opioids prescribed decreased between 2010 and 2015.

Majority of opioid prescriptions are written for patients with mental disorders

Among the nearly 40 million Americans who have a mental health condition, about 19% use prescription opioids.

Opioids often prescribed to back pain patients with depression

Researchers found that back pain patients are also more likely to get higher doses of opioids.

Use of ketamine for pain management and treatment of depression

Ketamine may alleviate depression, pain, and adverse effects associated with opioid treatment.

Opioid use before TKA causes less pain relief

Clinicians should consider limiting pre-TKA opioid prescriptions to optimize the benefits of TKA.

PA programs may need more focus on opioid prescribing practices

Many PA students and practicing PAs did not feel that their PA program adequately trained them to screen for opioid abuse.

Corticosteroids for sore throat: a mixed bag of results

Oral corticosteroids could be an alternative symptomatic treatment for acute sore throat, which is a significant burden in primary care and a source of inappropriate antibiotic prescribing.

Short-term oral corticosteroid use associated with increased risk for sepsis, venous thromboembolism

Approximately 1 in 5 American adults use corticosteroids in the short term, which is associated with an increased risk for sepsis, venous thromboembolism, and fracture.

Mindfulness-based stress reduction may improve low back pain

Mindfulness-based stress reduction was associated with short-term benefits for pain intensity and physical functioning.

Recommended dose of IV acetaminophen may be insufficient for multiple-trauma patients

Administration of acetaminophen at the recommended dosage yields serum concentrations below 10 µg/mL due to increased elimination.

Surgery patients may have higher risk of opioid addiction

Researchers found that some surgery patients may face a higher risk of becoming dependent on opioids.

CDC's opioid guideline prompts clinician concerns

The recently released CDC guidelines on opioid prescribing remain a topic of debate.

Radiofrequency treatment effective for refractory chronic joint pain

Radiofrequency treatment is an effective option for treating refractory chronic knee, hip, and shoulder joint pain.

Perioperative care for acute pain management

Patients with chronic pain who are hospitalized have a higher risk of morbidity and mortality, longer lengths of stay, and more frequent readmissions than patients without chronic pain.

Glucocorticoid injection offers relief for lower back pain

At 1 month after the intervention, the percentage of responders was higher in the GC IDI group than the control group.

Opioid and benzodiazepine combination use significantly increases overdose risk

The drug combination significantly contributes to the overall population risk of opioid overdose.

Children more likely to have a headache before a stroke than adults

Although ischemic strokes are still very rare in children, 46% of pediatric ischemic stroke patients over 3 years of age said they had a headache before the stroke.

Opioids for chronic pain: a new clinical guideline from the VA and Department of Defense

The Veterans Administration and Department of Defense issue a clinical practice guideline regarding opioid therapy for chronic pain in veterans.

Noninvasive treatment for low back pain: a new clinical guideline from ACP

The ACP has released 3 recommendations for the treatment of patients with acute, subacute, and chronic low back pain.

Intravenous lidocaine safe for reducing pain in ICU patients

Intravenous lidocaine is safe for reducing pain in patients in the ICU with varying degrees of organ dysfunction.

NSAIDs have little effect for spinal pain

The researchers estimated that only 1 in 6 patients gained a benefit from taking NSAIDs.

Migraine increases stroke risk in surgical patients

Surgical patients with a history of migraine have an increased risk of perioperative ischemic stroke and a higher 30-day hospital readmission rate.

Psychiatric, behavioral conditions linked to future long-term opioid use

Patients diagnosed with a prior psychiatric condition have increased odds of long-term opioid receipt than patients without these conditions.

Crizanlizumab reduces sickle cell-related pain

Treatment with high-dose crizanlizumab resulted in an annual rate of sickle cell-related pain crises that was 45.3% lower compared with placebo.

Shared decision making boosts patients' knowledge of acute coronary syndrome risk

The use of a decision aid in patients at risk of acute coronary syndrome increased patient knowledge about their risk.

American Chronic Pain Association issues toolkit for clinicians

The toolkit will provide healthcare professionals with adequate tools to manage their patients' pain.

Increased naloxone prices could affect rates of opioid-related mortality

Researchers identify strategies that could ensure access to naloxone.

Virtual reality game may help relieve phantom limb pain

Recent data suggests that a virtual reality game could reduce pain by as much as one-half.

Outpatient program may be effective for pain self-management

A program based on cognitive behavioral therapy and physical exercise could improve pain self-management in patients with complex pain.

FDA approves new drug for postmenopausal pain during sex

Intrarosa provides an additional treatment option for women with dyspareunia caused by vulvar and vaginal atrophy.

Quality improvement intervention helps pain management for seniors in the ER

Researchers conducted an examination in patients over 65 years with moderate-to-severe pain in an academic emergency department.

More than half of US citizens have a chronic health condition

Conditions such as chronic disease, mental illness, or substance abuse commonly overlap with each other and with poverty, which contributes to poor health.

Barriers remain in patients' acceptance of naloxone use in primary care

Patients would like more thorough conversations with their primary care physician over the use of naloxone.

Comparing treatments for pediatric migraines

No significant differences were observed among treatments for pediatric migraines.

Treatment costs lower with pregabalin vs gabapentin for peripheral neuropathic pain

The average total cost was lower for pregabalin treatment due to lower use of concomitant medications, fewer primary care visits, and fewer sick days.

Pain relief during labor may lower risk of postpartum depression

Women who received epidural pain relief during labor had lower scores on the Edinburgh Postnatal Depression Scale.

Placebo treatments may help patients with chronic lower back pain

Patients who knew they were taking a placebo pill still experienced less lower back pain.

DEA reverses plan to ban potential opioid alternative kratom

After public opposition, the DEA has withdrawn its plan to classify the kratom plant as a schedule 1 substance.

Complementary health approaches frequently used for musculoskeletal pain disorders

Data from the CDC's National Health Statistics Reports show that more than half of adults in the United States have a musculoskeletal pain disorder.

Controversy over CDC guidelines on prescribing opioids for chronic pain

Guidelines created in response to the opioid epidemic in the United States have caused controversy in the medical community.

Nonmedical use of prescription opioids in adolescence leads to substance use disorder symptoms in adulthood

Using medical or nonmedical prescribed opioids in adolescence may lead to alcohol, drug, and mental health disorders in adulthood.

Massage therapy may be beneficial for surgical pain

Massage therapy appears to be efficacious for reducing pain and anxiety in patients who are about to undergo or are recovering from surgical procedures.

Platelet-rich plasma SIJ injection cuts low back pain

The researchers found that patients who received the injection had significantly lower intensity of pain at six weeks and at three months compared with patients who didn't.

New treatments relieve pain for patients with cervical disc herniation

Patients who suffer from cervical disc herniation can find relieve in percutaneous nucleoplasty (PCN) and pulsed radio frequency (PRF).

The FDA approves first drug for Duchenne muscular dystrophy

Data showed an increase in dystrophin production that could predict clinical benefit among patients with DMD.

Neuropathic pain is reduced by pregabalin

Pregabalin significantly improves pain irrespective of the time since pain onset.

Using neuroimaging in chronic pain management

Developments in functional, structural, and neurochemical imaging could help predict individuals with acute pain who are likely to progress to chronic pain.

Oxycodone/naloxone may be beneficial for managing pain after total knee replacement

Oxycodone/naloxone may provide effective analgesia and improve patients' ability to participate in physiotherapy.

New guideline for managing kidney stones is released

Guideline from the American Urological Association has been revised to incorporate the management of patients with staghorn renal stones.

Prescribing practices influence opioid dependency

Patients provided with at least 2 refills were 2.25 times more likely to develop an opioid dependency.

Medicare patients rarely prescribed buprenorphine-naloxone

Addiction medicine specialists prescribed the most prescriptions for buprenorphine-naloxone.

Sedentary behavior linked to chronic pain in children

Prepubertal children who regularly engage in sedentary behavior have an increased likelihood of experiencing various pain conditions.

Metamizole may be an acceptable alternative to NSAIDs

Metamizole should be considered in patients with contraindications to NSAIDs.

ASCO issues guidelines for chronic pain in patients with a history of adult cancer

Screening for pain at every visit is recommended, and management and treatment options are specified.

Appendicitis an important differential diagnosis in the elderly

Older adults presenting with abdominal pain should be screened for appendicitis.

Chronic visceral pain management

Pain management specialists may have an important role to play in the treatment of patients with chronic visceral pain.

State restrictions not associated with reduced opioid misuse among disabled adults

The adoption of various state laws did not affect rates of opioid prescription or strength of dose.

Chest pain in ER patients rarely life threatening

Only 5.5% of ER patients are diagnosed with 1 of 6 life threatening conditions.

Parental management of child's postoperative pain

Despite being well-informed, many parents struggled to manage their child's postoperative pain.

Long-acting opioid therapy linked to increased mortality risk

Patients with chronic, noncancer pain who were treated with long-acting opioid therapy had a 1.6 times greater risk of death.

New opioid use common post-hospital discharge among Medicare beneficiaries

After an acute hospitalization, many Medicare beneficiaries submit pharmacy claims for opioid prescriptions.

Smartphone app helps circumvent unnecessary testing for chest pain in ED patients

The HEART pathway app provides doctors in the ED with a digital application an already proven method of assessment.

Naloxone coprescription reduces opioid-related ER visits

Patients on opioids for chronic pain who were coprescribed naloxone had 47% fewer opioid-related ER visits.

Many patients lack knowledge about NSAIDs and their risks

Despite the widespread use of NSAIDs to treat pain, many patients lack knowledge about these medications and their risks.

IV lidocaine plus amitriptyline has no impact in fibromyalgia

No difference was recorded between patients treated with lidocaine plus amitriptyline versus patients treated with acetaminophen and tramadol.

Chronic migraines may be linked to vitamin deficiencies

Researchers examined a possible link between vitamin D, riboflavin, coenzyme Q10, and chronic migraines.

For chronic low back pain, opioids only moderately effective

For patients with chronic low back pain, opioids may provide some short-term relief but are unlikely to be effective within recommended doses.

Acceptance and commitment therapy effectively treats chronic pain

Acceptance and commitment therapy can have positive outcomes in adults with chronic pain.

Chronic pain management in veterans

Chronic pain in veterans has been linked to mental health conditions and high use of healthcare resources.

Cannabinoids may provide moderate benefit for rheumatic conditions

Researchers found no serious adverse events related to treatment with cannabinoids.

Migraines may increase CVD risk in women

Women who experience migraines had a 50% greater risk for developing major CVD.

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