Pain News Archive

Pain during IUD insertion reduced with lidocaine nerve block

A 1% paracervical nerve block may be useful for reducing patient-reported pain during IUD insertion.

Effects of cannabis treatment in adult patients with PTSD

Researchers found that cannabis may alleviate neuropathic pain, but is not associated with benefit for adults with PTSD.

Clinicians may be overprescribing gabapentinoids for pain

Gabapentinoids may be overprescribed, in part as a response to the opioid epidemic.

NASEM report outlines strategy to combat opioid epidemic

The FDA commissioned the report to provide an update on current evidence on research, care, and education in the pain field, and to identify actionable measures for the FDA to more adequately address the ongoing opioid epidemic.

CDC: Opioid prescription rate remains high, inconsistent in the United States

However, the number of opioids prescribed decreased between 2010 and 2015.

Majority of opioid prescriptions are written for patients with mental disorders

Among the nearly 40 million Americans who have a mental health condition, about 19% use prescription opioids.

Opioids often prescribed to back pain patients with depression

Researchers found that back pain patients are also more likely to get higher doses of opioids.

Use of ketamine for pain management and treatment of depression

Ketamine may alleviate depression, pain, and adverse effects associated with opioid treatment.

Opioid use before TKA causes less pain relief

Clinicians should consider limiting pre-TKA opioid prescriptions to optimize the benefits of TKA.

PA programs may need more focus on opioid prescribing practices

Many PA students and practicing PAs did not feel that their PA program adequately trained them to screen for opioid abuse.

Corticosteroids for sore throat: a mixed bag of results

Oral corticosteroids could be an alternative symptomatic treatment for acute sore throat, which is a significant burden in primary care and a source of inappropriate antibiotic prescribing.

Short-term oral corticosteroid use associated with increased risk for sepsis, venous thromboembolism

Approximately 1 in 5 American adults use corticosteroids in the short term, which is associated with an increased risk for sepsis, venous thromboembolism, and fracture.

Mindfulness-based stress reduction may improve low back pain

Mindfulness-based stress reduction was associated with short-term benefits for pain intensity and physical functioning.

Recommended dose of IV acetaminophen may be insufficient for multiple-trauma patients

Administration of acetaminophen at the recommended dosage yields serum concentrations below 10 µg/mL due to increased elimination.

Surgery patients may have higher risk of opioid addiction

Researchers found that some surgery patients may face a higher risk of becoming dependent on opioids.

CDC's opioid guideline prompts clinician concerns

The recently released CDC guidelines on opioid prescribing remain a topic of debate.

Radiofrequency treatment effective for refractory chronic joint pain

Radiofrequency treatment is an effective option for treating refractory chronic knee, hip, and shoulder joint pain.

Perioperative care for acute pain management

Patients with chronic pain who are hospitalized have a higher risk of morbidity and mortality, longer lengths of stay, and more frequent readmissions than patients without chronic pain.

Glucocorticoid injection offers relief for lower back pain

At 1 month after the intervention, the percentage of responders was higher in the GC IDI group than the control group.

Opioid and benzodiazepine combination use significantly increases overdose risk

The drug combination significantly contributes to the overall population risk of opioid overdose.

Children more likely to have a headache before a stroke than adults

Although ischemic strokes are still very rare in children, 46% of pediatric ischemic stroke patients over 3 years of age said they had a headache before the stroke.

Opioids for chronic pain: a new clinical guideline from the VA and Department of Defense

The Veterans Administration and Department of Defense issue a clinical practice guideline regarding opioid therapy for chronic pain in veterans.

Noninvasive treatment for low back pain: a new clinical guideline from ACP

The ACP has released 3 recommendations for the treatment of patients with acute, subacute, and chronic low back pain.

Intravenous lidocaine safe for reducing pain in ICU patients

Intravenous lidocaine is safe for reducing pain in patients in the ICU with varying degrees of organ dysfunction.

NSAIDs have little effect for spinal pain

The researchers estimated that only 1 in 6 patients gained a benefit from taking NSAIDs.

Migraine increases stroke risk in surgical patients

Surgical patients with a history of migraine have an increased risk of perioperative ischemic stroke and a higher 30-day hospital readmission rate.

Psychiatric, behavioral conditions linked to future long-term opioid use

Patients diagnosed with a prior psychiatric condition have increased odds of long-term opioid receipt than patients without these conditions.

Crizanlizumab reduces sickle cell-related pain

Treatment with high-dose crizanlizumab resulted in an annual rate of sickle cell-related pain crises that was 45.3% lower compared with placebo.

Shared decision making boosts patients' knowledge of acute coronary syndrome risk

The use of a decision aid in patients at risk of acute coronary syndrome increased patient knowledge about their risk.

American Chronic Pain Association issues toolkit for clinicians

The toolkit will provide healthcare professionals with adequate tools to manage their patients' pain.

Increased naloxone prices could affect rates of opioid-related mortality

Researchers identify strategies that could ensure access to naloxone.

Virtual reality game may help relieve phantom limb pain

Recent data suggests that a virtual reality game could reduce pain by as much as one-half.

Outpatient program may be effective for pain self-management

A program based on cognitive behavioral therapy and physical exercise could improve pain self-management in patients with complex pain.

FDA approves new drug for postmenopausal pain during sex

Intrarosa provides an additional treatment option for women with dyspareunia caused by vulvar and vaginal atrophy.

Quality improvement intervention helps pain management for seniors in the ER

Researchers conducted an examination in patients over 65 years with moderate-to-severe pain in an academic emergency department.

More than half of US citizens have a chronic health condition

Conditions such as chronic disease, mental illness, or substance abuse commonly overlap with each other and with poverty, which contributes to poor health.

Barriers remain in patients' acceptance of naloxone use in primary care

Patients would like more thorough conversations with their primary care physician over the use of naloxone.

Comparing treatments for pediatric migraines

No significant differences were observed among treatments for pediatric migraines.

Treatment costs lower with pregabalin vs gabapentin for peripheral neuropathic pain

The average total cost was lower for pregabalin treatment due to lower use of concomitant medications, fewer primary care visits, and fewer sick days.

Pain relief during labor may lower risk of postpartum depression

Women who received epidural pain relief during labor had lower scores on the Edinburgh Postnatal Depression Scale.

Placebo treatments may help patients with chronic lower back pain

Patients who knew they were taking a placebo pill still experienced less lower back pain.

DEA reverses plan to ban potential opioid alternative kratom

After public opposition, the DEA has withdrawn its plan to classify the kratom plant as a schedule 1 substance.

Complementary health approaches frequently used for musculoskeletal pain disorders

Data from the CDC's National Health Statistics Reports show that more than half of adults in the United States have a musculoskeletal pain disorder.

Controversy over CDC guidelines on prescribing opioids for chronic pain

Guidelines created in response to the opioid epidemic in the United States have caused controversy in the medical community.

Nonmedical use of prescription opioids in adolescence leads to substance use disorder symptoms in adulthood

Using medical or nonmedical prescribed opioids in adolescence may lead to alcohol, drug, and mental health disorders in adulthood.

Massage therapy may be beneficial for surgical pain

Massage therapy appears to be efficacious for reducing pain and anxiety in patients who are about to undergo or are recovering from surgical procedures.

Platelet-rich plasma SIJ injection cuts low back pain

The researchers found that patients who received the injection had significantly lower intensity of pain at six weeks and at three months compared with patients who didn't.

New treatments relieve pain for patients with cervical disc herniation

Patients who suffer from cervical disc herniation can find relieve in percutaneous nucleoplasty (PCN) and pulsed radio frequency (PRF).

The FDA approves first drug for Duchenne muscular dystrophy

Data showed an increase in dystrophin production that could predict clinical benefit among patients with DMD.

Neuropathic pain is reduced by pregabalin

Pregabalin significantly improves pain irrespective of the time since pain onset.

Using neuroimaging in chronic pain management

Developments in functional, structural, and neurochemical imaging could help predict individuals with acute pain who are likely to progress to chronic pain.

Oxycodone/naloxone may be beneficial for managing pain after total knee replacement

Oxycodone/naloxone may provide effective analgesia and improve patients' ability to participate in physiotherapy.

New guideline for managing kidney stones is released

Guideline from the American Urological Association has been revised to incorporate the management of patients with staghorn renal stones.

Prescribing practices influence opioid dependency

Patients provided with at least 2 refills were 2.25 times more likely to develop an opioid dependency.

Medicare patients rarely prescribed buprenorphine-naloxone

Addiction medicine specialists prescribed the most prescriptions for buprenorphine-naloxone.

Sedentary behavior linked to chronic pain in children

Prepubertal children who regularly engage in sedentary behavior have an increased likelihood of experiencing various pain conditions.

Metamizole may be an acceptable alternative to NSAIDs

Metamizole should be considered in patients with contraindications to NSAIDs.

ASCO issues guidelines for chronic pain in patients with a history of adult cancer

Screening for pain at every visit is recommended, and management and treatment options are specified.

Appendicitis an important differential diagnosis in the elderly

Older adults presenting with abdominal pain should be screened for appendicitis.

Chronic visceral pain management

Pain management specialists may have an important role to play in the treatment of patients with chronic visceral pain.

State restrictions not associated with reduced opioid misuse among disabled adults

The adoption of various state laws did not affect rates of opioid prescription or strength of dose.

Chest pain in ER patients rarely life threatening

Only 5.5% of ER patients are diagnosed with 1 of 6 life threatening conditions.

Parental management of child's postoperative pain

Despite being well-informed, many parents struggled to manage their child's postoperative pain.

Long-acting opioid therapy linked to increased mortality risk

Patients with chronic, noncancer pain who were treated with long-acting opioid therapy had a 1.6 times greater risk of death.

New opioid use common post-hospital discharge among Medicare beneficiaries

After an acute hospitalization, many Medicare beneficiaries submit pharmacy claims for opioid prescriptions.

Smartphone app helps circumvent unnecessary testing for chest pain in ED patients

The HEART pathway app provides doctors in the ED with a digital application an already proven method of assessment.

Naloxone coprescription reduces opioid-related ER visits

Patients on opioids for chronic pain who were coprescribed naloxone had 47% fewer opioid-related ER visits.

Many patients lack knowledge about NSAIDs and their risks

Despite the widespread use of NSAIDs to treat pain, many patients lack knowledge about these medications and their risks.

IV lidocaine plus amitriptyline has no impact in fibromyalgia

No difference was recorded between patients treated with lidocaine plus amitriptyline versus patients treated with acetaminophen and tramadol.

Chronic migraines may be linked to vitamin deficiencies

Researchers examined a possible link between vitamin D, riboflavin, coenzyme Q10, and chronic migraines.

For chronic low back pain, opioids only moderately effective

For patients with chronic low back pain, opioids may provide some short-term relief but are unlikely to be effective within recommended doses.

Acceptance and commitment therapy effectively treats chronic pain

Acceptance and commitment therapy can have positive outcomes in adults with chronic pain.

Chronic pain management in veterans

Chronic pain in veterans has been linked to mental health conditions and high use of healthcare resources.

Cannabinoids may provide moderate benefit for rheumatic conditions

Researchers found no serious adverse events related to treatment with cannabinoids.

Migraines may increase CVD risk in women

Women who experience migraines had a 50% greater risk for developing major CVD.

FDA approves buprenorphine implant for opioid dependence

Probuphine is the first buprenorphine implant approved for the maintenance treatment of opioid dependence.

Probiotics improve clinical, metabolic status in rheumatoid arthritis

After 8 weeks, patients with rheumatoid arthritis who took probiotics showed improvements in disease activity and metabolic health.

Pain complexities in rheumatoid arthritis

Nearly 12% of patients in remission from RA still experience clinically significant pain.

Migraine medications not linked to stroke risk

For patients with basilar or hemiplegic migraines, two common migraine medications do not increase the risk of stroke and cardiovascular events.

Effective strategies to prescribe opioids, provide pain relief in hospital settings urgently needed

Clinicians in hospital settings need strategies in place to safely provide opioid pain relief to hospitalized patients.

Hospitalizations due to opioid abuse, dependence increasing significantly

Since 2002, the number of hospitalizations due to opioid abuse and dependence has increased by 72%.

Benefit of spinal manipulation not clinically meaningful

Spinal manipulation patients experienced statistically, but not clinically significant, reductions in pain and disability.

High fatigue common in psoriatic arthritis

Nearly 50% of patients with psoriatic arthritis report elevated levels of fatigue.

Sleep problems in young adults associated with chronic pain later in life

Young adults with sleep problems have increased risks of developing chronic pain and experiencing worsening in pain severity.

Pharmacotherapy options for noncancer pain: an efficacy review

Although opioids are often prescribed for noncancer pain, a new review shows that they are no more effective than acetaminophen or NSAIDs.

Mindfulness, CBT can reduce chronic low back pain

Mindfulness-based stress reduction and cognitive behavior therapy may be useful to improve chronic low back pain.

CDC releases guideline for prescribing opioids for chronic pain in primary care

The CDC's new guideline regarding opioid therapy for chronic pain focuses on balancing potential benefits and harms to the patient.

Monitoring program improves chronic pain management in primary care

Patient monitoring and pain specialist support can help primary care practitioners better manage their patients taking opioids for chronic pain.

People with asthma more likely to develop chronic migraine

In a study of 4,446 Americans, more than 5% of people with asthma developed chronic migraine, compared to 2.5% of those without.

Drug combos not more effective than naproxen alone for acute low back pain

When compared to naproxen alone, the combination of either cyclobenzaprine or oxycodone/acetaminophene plus naproxen does not as effectively improve acute, nontraumatic lower back pain.

Gap exists between patients, clinicians in osteoarthritis care

For osteoarthritis care, complexity, dissonance, and prioritization are three barriers in clinician and patient communication.

Alternative therapies may be beneficial for patients with chronic neck pain

Trial results show that patients with chronic neck pain benefit from acupuncture and Alexander Technique treatment in conjunction with their usual pain management.

NIH will support more research on myalgic encephalomyelitis/chronic fatigue syndrome

The NIH has pledged to renew research efforts into the cause and treatment of myalgic encephalomyelitis/chronic fatigue syndrome.

PAMORA for opioid-induced constipation

Naloxegol functions as a peripherally acting mu-opioid receptor antagonist in tissues such as the gastrointestinal tract, thereby decreasing the constipating effects of opioids.

DPP-4 inhibitors may cause severe joint pain in type 2 diabetes

The FDA released a warning that DPP-4 inhibitors may lead to severe joint pain in patients with T2DM.

OxyContin approved for children aged 11 and older

The FDA has approved a pediatric indication for OxyContin in patients as young as 11 years.

Chronic pain common in HIV patients

Chronic pain and depression symptoms are common among patients with HIV.

Prednisone improves function in acute radiculopathy

Oral prednisone can improve 
functional status in patients 
with acute radiculopathy due to a herniated disk but does not improve pain.

Buprenorphine may benefit patients with opioid dependence

Emergency-department initiated buprenorphine treatment may increase addiction treatment 
and decrease opioid use in patients with opioid dependence

Patients with chronic pain do not discuss use of alternative therapies with clinicians

A significant number of pain patients who use alternative therapies have not discussed them with their clinicians.

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