Pain Consultations News
Comprehensive bipartisan package earmarks billions of dollars to fight opioid abuse in the United States.
Cassipa combines buprenorphine, an opioid (partial agonist-antagonist), and naloxone, an opioid antagonist.
In a randomized control trial, researchers found that internet-delivered exposure therapy was more cost-effective for patients with fibromyalgia than a waitlist control, which did not involve any treatment during the experimental phase of the study.
An estimated 31 million Americans will experience low back pain at some point in their lifetime.
Recall due to mismarked dosage cup in 4-oz bottles of Children's Advil Suspension Bubble Gum Flavored.
An elderly man presents to the emergency department with elbow and biceps pain after falling on the stairs.
Although literature indicates bidirectional associations between sleep disturbances and pain, few longitudinal studies have examined the role of sleep disturbances in contributing to chronic pain.
No significant reduction in percentage of patients prescribed opioids after general surgery.
Integrating graded in vivo exposure into the management of chronic lower back pain may result in improved treatment efficacy and reduced pain-related fear.
Increase in mean OMEs filled in initial opioid rx after hydrocodone's change from schedule III to II.
The number of patients prescribed opioids and visiting an emergency department or requiring hospitalization decreased from 2009 to 2015.
Spinal manipulative therapy plus exercise more effective than exercise alone over 1-year period.
Dose-response association with highest odds of opioid-related death with high-dose pregabalin.
Children with abdominal pain commonly had clinically significant anxiety, moderate disability, pain.
A low-literacy, pain self-management program delivered one-on-one by a health educator or in groups with lectures from experts over a period of 6 months may improve chronic pain outcomes.
Differences exist in race and gender in patients with chronic lower back pain, especially in pain sensitivity and severity due to aftersensations from mechanical punctuate pain and deep muscle hyperalgesia.
Findings based on analysis of motorcycle accident victims by helmet use.
There is a lack of evidence supporting the benefits of combination drug therapy over monotherapy for the management of low back pain and sciatica.
Variation exists in opioid prescribing practices among clinicians in single-hospital systems, which prompts concern about the potential for opioid overprescribing.
Cumulative incidence of opioid-related adverse events was 38.3 per 100,000 prescriptions.
This novel agent has low permeability across the blood-brain barrier, which slows its rate of entry into the brain and reduces dopamine release.
Postpartum Pain Management Recommendations From the American College of Obstetricians and Gynecologists
A committee from the American College of Obstetricians and Gynecologists formulated several recommendations for safely managing pain and fatigue in women during the early postpartum period.
Odds of pre-op opioid use up with age 31 to 40 years, tobacco use, illicit drug use, depression.
American emergency medicine physicians have been taking measures to address the ongoing opioid crisis, which affects emergency departments throughout the country.
Radiofrequency denervation, typically used to treat lumbar and cervical zygapophyseal joint pain, has shown efficacy in treating thoracic zygapophyseal joint pain.
Only 44 of parents would definitely go to ER if their child had headache that didn't improve with medication.
Investigators examined rates, predictors, and outcomes of neuroimaging in pediatric and adolescent patients who presented to the ED with a headache.
Consensus guidelines regarding the use of ketamine for the management of acute pain have been approved.
Surgeon General Jerome M. Adams, M.D., M.P.H., has urged more Americans to carry naloxone, an FDA-approved medication that can be delivered via nasal mist or injection and can temporarily suspend the effects of opioid overdose.
A panel discussion event held at the US Food and Drug Administration gathered patients with chronic pain and FDA officials, to reconcile concerns around prescriptions of opioid medications with the needs of these patient populations.
Commission makes 6 recommendations to meet 2030 goals for non-communicable diseases
Chronic low back pain (LBP) defined as persistent or fluctuating musculoskeletal pain of lower back and lumbar spine lasting >3 months.
Current oral contraceptive products contain lower doses of estrogen than those used in the past, prompting reconsideration of risks and benefits.
In adults with sickle cell disease, higher daily opioid use may be associated with poorer health-related quality of life.
A study assessing the impact of upscheduling of hydrocodone combined medications on APRN practices in Oklahoma revealed significant barriers to effective pain management.
Researchers deployed a survey to individuals who had received treatment for opioid use disorder to assess their use of buprenorphine.
The phase 3 SUMMIT-07 trial assessed the safety, efficacy, and tolerability of a new mu-opioid receptor agonist analgesic in adults with moderate to severe chronic lower back pain.
Investigators assessed the potential for abuse associated with NKTR-181, a new mu-opioid receptor agonist analgesic.
A combination of naltrexone induction and psychoeducational counseling was found to facilitate transition from active opioid use and buprenorphine maintenance in individuals with opioid use disorder.
The budesonide extended-release formulation was found to be safe and well tolerated for the remission of ulcerative colitis, regardless of age or gender.
The Company indicated that they will work towards an New Drug Application submission for the treatment in the second half of 2018.
Pediatric exposure to buprenorphine can result in serious adverse outcomes, especially among children aged younger than 6 years.
Belief in a long recovery, many symptoms attributed to pain negatively tied to improvement
With the increasing number of patients presenting to surgery with opioid tolerance, clinicians should be familiar with their specific analgesic needs.
Minority of opioid overdose survivors receive MOUD; buprenorphine, MMT linked to reduced mortality
In patients receiving opioid substitution treatment for opioid use disorder (mainly involving heroin), those exhibiting a rapid decline in heroin use were found to be more likely to have successful treatment outcomes.
Electrical pulses are sent through small needles that are inserted in the ear to combat the early stages of detoxification, leading to stabilization.
Patients with migraine may exhibit higher prevalence of restless leg syndrome, fibromyalgia, and depressive symptoms compared with individuals not experiencing migraines.
Adding corticosteroids to epidural lidocaine injections does not improve patient-reported pain or function at 12 months.
The U.S. Food and Drug Administration has issued warnings to 9 online companies selling illegal opioid medications on 53 websites, in direct violation of the Federal Food, Drug, and Cosmetic Act.
Cryoablation also cuts the need for opioids at 24 hours post-treatment and at three months
Burden of deaths up; most patients receiving opioid analgesics use immediate-release formulations
Posttraumatic stress disorder symptoms may be associated with higher levels of acute pain and pain interference in low-income inner city women.
Lucemyra is an oral selective alpha 2-adrenergic receptor agonist
Impact of medications on mother-infant dyad should be considered, as many women breastfeed
Migraine is highly prevalent in children and adolescents, affecting almost 10% of children between 5 and 15 years old and 30% of adolescents between 15 and 19 years old.
The efficacy of Aimovig was evaluated as a preventive treatment of episodic or chronic migraine in 3 randomized, double-blind, placebo-controlled studies: 2 studies in patients with episodic migraine (4-14 migraine days per month) and 1 study in patients with chronic migraine (≥15 headache days per month with ≥8 migraine days per month).
Improvements in low back pain intensity and disability among active-duty military personnel
Oral medication, botulinum toxin type A injections, and endoscopic decompression surgery were all compared in the treatment of patients with frontal secondary headaches due to STN and SON configuration.
Investigators examined presenting features of migraine vs arterial ischemic stroke in children presenting to the emergency department.
Many patients reported unsafe storage and failure to dispose of opioids at one- and 6-month follow-up
Individuals with chronic vs episodic migraine may be more likely to experience chronic back pain, chronic pain, neck pain, anxiety, and depression.
From 2010 to 2016, synthetic opioid involvement up from 14.3 to 45.9% of opioid-related deaths
Intrathecal drug delivery systems and spinal cord stimulation have shown promise for the treatment of cancer pain in initial studies.
A combination of self-care education, aerobic and strength-training exercise, and spinal manipulation therapy may provide greater pain relief and improved treatment satisfaction compared with exercise only in adolescents with low back pain.
Based on data from multiple sources, many opioid-overdose deaths seem to be suicides
The use of high doses of opioids — particularly long-acting opioids — during surgery may increase the risk for 30-day readmission.
At discharge, 92.2% of patients received an opioid prescription; nearly 63% unused
Post-op pain strongly linked to number of classes of non-opioid analgesics used, remifentanil use
It is important for clinicians to quickly and accurately determine potential underlying causes and to prescribe treatments that take into account comorbidities and medications that older patients may be taking for them.
Lower numeric rating scale pain scores on ambulation on postoperative days zero, one, and two
National Institutes of Health Director, Francis Collins, MD, PhD, announced on April 4, 2018 the launch of the Helping to End Addiction Long-Term Initiative.
Heavy use in Crohn's, heavy or moderate use in ulcerative colitis tied to increased risk of death
Findings based on two-year follow-up of a large, community-dwelling cohort in Malaysia
Group cognitive behavioral therapy and pain education may be more effective than usual care for improving pain and physical function in patients presenting with chronic pain at low-income clinics.
Tai chi interventions may be more effective at treating fibromyalgia than aerobic exercise.
FDA has called on social media companies and internet service providers to take a proactive approach in curbing online selling of opioids through their platforms.
The two most prevalent HIV symptoms, fatigue and muscle aches, are more common in women than men and can worsen with menopause.
The rate of ER visits for suspected opioid-related overdoses has increased by a mean of 5.6% per quarter.
Individuals with gluten neuropathy experienced less peripheral neuropathic pain when adhering to strict gluten-free diets.
Transcutaneous electrical nerve stimulation may be ineffective in treating, relieving lower back pain when compared with other nerve stimulation therapies.
Both modified cognitive behavioral therapy and pain education interventions were associated with improved pain in patients with disadvantaged backgrounds.
Intravenous, patch lidocaine might be effective in treating, preventing chronic pain.
The quality of sleep partly relieved the correlation between PSTD and pain intensity, interference.
Functional magnetic resonance imaging was used to monitor brain activity in patients with osteoarthritis who were administered either genuine or placebo electroacupuncture.
Migraines are linked to cardiovascular events, including myocardial infarction, VTE, and stroke.
Nearly all of kratom's major compounds bind to opioid receptors in the human brain, and 2 of the top 5 most prevalent compounds activate those receptors, FDA Commissioner Scott Gottlieb said in a statement. In addition, there have been 44 reported deaths associated with the use of kratom, often in combination with other substances, Gottlieb said.
A FNP reflects on his experiences working with pain management patients prescribed opioids.
A combination of psychoeducation, cognitive-based therapy, visualization, and breathing exercises may represent a tolerable and readily accepted complementary therapeutic approach for adolescent patients with chronic pain.
Clinicians are in the unique position to educate and counsel middle-aged adults about their opioid use and influence strategies needed to provide effective pain control.
It can be difficult to care for complex patients when they need services that do not exist.
A 1% paracervical nerve block may be useful for reducing patient-reported pain during IUD insertion.
Co-prescribing naloxone and opioids in primary care is recommended for patients who have a high risk for opioid overdose.
Researchers found that cannabis may alleviate neuropathic pain, but is not associated with benefit for adults with PTSD.
Current surgical and prescribing practices may have a hand in exacerbating the nation's burgeoning opioid epidemic.
Gabapentinoids may be overprescribed, in part as a response to the opioid epidemic.
The FDA commissioned the report to provide an update on current evidence on research, care, and education in the pain field, and to identify actionable measures for the FDA to more adequately address the ongoing opioid epidemic.
However, the number of opioids prescribed decreased between 2010 and 2015.
Among the nearly 40 million Americans who have a mental health condition, about 19% use prescription opioids.
Researchers found that back pain patients are also more likely to get higher doses of opioids.