Chronic Pain Leads to Higher Opioid Doses and Lower QoL in Sickle Cell Patients
Adult patients with sickle cell disease often experience a complex chronic pain syndrome that is frequently treated with long-term opioid regimens.
A low-literacy, pain self-management program delivered one-on-one by a health educator or in groups with lectures from experts over a period of 6 months may improve chronic pain outcomes.
Differences exist in race and gender in patients with chronic lower back pain, especially in pain sensitivity and severity due to aftersensations from mechanical punctuate pain and deep muscle hyperalgesia.
Cumulative incidence of opioid-related adverse events was 38.3 per 100,000 prescriptions.