Pain Management Information Center Archive

Two Minute Medicine

Pediatric palliative care outcome measures often miss quality of life

A systematic review of outcome measures found that only a minority addressed quality of life and patient (child) reported outcomes, and many did not measure psychometric properties.

Healthday AI-Based Smartphone App Can Help Cut Cancer Pain Severity

AI-Based Smartphone App Can Help Cut Cancer Pain Severity

App can cut both severity of advanced cancer patients' reported pain and hospital admissions.

News Workplace, Clinical Factors Linked to Employment Outcomes in Axial Spondyloarthritis

Workplace, Clinical Factors Linked to Employment Outcomes in Axial Spondyloarthritis

Data identified both clinical and employment factors that may predict poor work outcomes in patients with axial spondyloarthritis.

News Central Sensitization in Greater Trochanteric Pain Syndrome

Central Sensitization in Greater Trochanteric Pain Syndrome

Patients with greater trochanteric pain syndrome may have altered conditioned pain modulation, as well as a high number of pain locations associated with negative conditioned pain modulation.

News Two Screening Tools May Accurately Predict Transition From Acute to Chronic Low Back Pain

Two Screening Tools May Accurately Predict Transition From Acute to Chronic Low Back Pain

Two screening tools, the STarT Back Screening Tool and the Örebro Musculoskeletal Pain Questionnaire, may be useful in predicting the transition from subacute and acute to chronic low back pain.

News Guidelines on the Use of OnabotulinumtoxinA for Chronic Migraine

Guidelines on the Use of OnabotulinumtoxinA for Chronic Migraine

Researchers and pain experts formulated guidelines for the use of onabotulinumtoxinA for the management of chronic migraine.

News Stepped-Care Model Beneficial in Pain Management Practices in Primary Care

Stepped-Care Model Beneficial in Pain Management Practices in Primary Care

A stepped-care model of pain management implemented in primary care was successful in increasing the proportion of veteran patients reporting moderate to severe pain, as well as decreasing the use of opioids for pain management.

Healthday New Guidelines Issued for Patellofemoral Pain Management

New Guidelines Issued for Patellofemoral Pain Management

The National Athletic Trainers' Association has issued recommendations for identifying and managing patients with patellofemoral pain.

News OTC Analgesic Use High, Associated With Worse-Than-Expected Clinical Profiles

OTC Analgesic Use High, Associated With Worse-Than-Expected Clinical Profiles

The clinical profiles of patients taking over-the-counter pain medications were found to be poorer than expected, with a high prevalence of migraine headache and many reporting frequent and disabling pain for extended durations.

News Clinician Characteristics Associated With Outpatient Postoperative Opioid Prescribing

Clinician Characteristics Associated With Outpatient Postoperative Opioid Prescribing

Advanced practice providers were found to prescribe more opioids and in larger quantities compared with other physicians.

Healthday Gabapentin Superior to Pregabalin for Chronic Sciatica

Gabapentin Superior to Pregabalin for Chronic Sciatica

For patients with chronic sciatica, gabapentin is superior to pregabalin, with fewer and less severe adverse events.

News CDC Guideline for Opioid Prescribing May Have Effectively Reduced Opioid Prescribing Practices

CDC Guideline for Opioid Prescribing May Have Effectively Reduced Opioid Prescribing Practices

The Centers for Disease Control and Prevention's "Guideline for Prescribing Opioids for Chronic Pain" may have contributed to a further reduction in several opioid prescribing practices.

Healthday MRI Indicates Sacroiliitis in Some Healthy Individuals

MRI Indicates Sacroiliitis in Some Healthy Individuals

Considerable proportion of healthy individuals without back pain have MRI positive for sacroiliitis.

Healthday CDC: About One in 5 US Adults Has Chronic Pain

CDC: About One in 5 US Adults Has Chronic Pain

Higher prevalence of chronic pain, high-impact chronic pain for women, older adults, rural residents.

News Internet-Delivered Exposure Therapy Cost-Effective for Patients With Fibromyalgia

Internet-Delivered Exposure Therapy Cost-Effective for Patients With Fibromyalgia

In a randomized control trial, researchers found that internet-delivered exposure therapy was more cost-effective for patients with fibromyalgia than a waitlist control, which did not involve any treatment during the experimental phase of the study.

Feature Current Guidelines for Management of Low Back Pain

Current Guidelines for Management of Low Back Pain

An estimated 31 million Americans will experience low back pain at some point in their lifetime.

Healthday Pfizer Recalls a Type of Children's Liquid Advil

Pfizer Recalls a Type of Children's Liquid Advil

Recall due to mismarked dosage cup in 4-oz bottles of Children's Advil Suspension Bubble Gum Flavored.

News Call to Better Investigate the Associations Between Sleep Disturbances and Chronic Pain

Call to Better Investigate the Associations Between Sleep Disturbances and Chronic Pain

Although literature indicates bidirectional associations between sleep disturbances and pain, few longitudinal studies have examined the role of sleep disturbances in contributing to chronic pain.

Healthday Prescription Drug Monitoring Program May Not Cut Opioid Use

Prescription Drug Monitoring Program May Not Cut Opioid Use

No significant reduction in percentage of patients prescribed opioids after general surgery.

News Graded In Vivo Exposure Elements May Benefit Chronic Lower Back Pain Management

Graded In Vivo Exposure Elements May Benefit Chronic Lower Back Pain Management

Integrating graded in vivo exposure into the management of chronic lower back pain may result in improved treatment efficacy and reduced pain-related fear.

News Opioid-Related Emergency Department Visits, Hospitalization Rates Decrease From 2009 to 2015

Opioid-Related Emergency Department Visits, Hospitalization Rates Decrease From 2009 to 2015

The number of patients prescribed opioids and visiting an emergency department or requiring hospitalization decreased from 2009 to 2015.

Healthday Odds of Death Up With Exposure to Pregabalin, Opioids

Odds of Death Up With Exposure to Pregabalin, Opioids

Dose-response association with highest odds of opioid-related death with high-dose pregabalin.

News Low Literacy Self-Management Program for Chronic Pain May Be Effective

Low Literacy Self-Management Program for Chronic Pain May Be Effective

A low-literacy, pain self-management program delivered one-on-one by a health educator or in groups with lectures from experts over a period of 6 months may improve chronic pain outcomes.

News Chronic Low Back Pain Levels Vary Between Sex and Race

Chronic Low Back Pain Levels Vary Between Sex and Race

Differences exist in race and gender in patients with chronic lower back pain, especially in pain sensitivity and severity due to aftersensations from mechanical punctuate pain and deep muscle hyperalgesia.

Healthday Fewer Cervical Spine Injuries Seen With Motorcycle Helmet Use

Fewer Cervical Spine Injuries Seen With Motorcycle Helmet Use

Findings based on analysis of motorcycle accident victims by helmet use.

News Combination Therapies for Low Back Pain, Sciatica May Not Have Added Benefit

Combination Therapies for Low Back Pain, Sciatica May Not Have Added Benefit

There is a lack of evidence supporting the benefits of combination drug therapy over monotherapy for the management of low back pain and sciatica.

News Wide Variations in Opioid Prescribing Practices for Surgical Procedures

Wide Variations in Opioid Prescribing Practices for Surgical Procedures

Variation exists in opioid prescribing practices among clinicians in single-hospital systems, which prompts concern about the potential for opioid overprescribing.

Healthday Outpatient Opioid Prescriptions for Children Often Filled

Outpatient Opioid Prescriptions for Children Often Filled

Cumulative incidence of opioid-related adverse events was 38.3 per 100,000 prescriptions.

News FDA to Review Novel Opioid Analgesic for Chronic Low Back Pain

FDA to Review Novel Opioid Analgesic for Chronic Low Back Pain

This novel agent has low permeability across the blood-brain barrier, which slows its rate of entry into the brain and reduces dopamine release.

News Postpartum Pain Management Recommendations From the American College of Obstetricians and Gynecologists

Postpartum Pain Management Recommendations From the American College of Obstetricians and Gynecologists

A committee from the American College of Obstetricians and Gynecologists formulated several recommendations for safely managing pain and fatigue in women during the early postpartum period.

Healthday Preoperative Opioids Used by Nearly One-Quarter of Surgical Patients

Preoperative Opioids Used by Nearly One-Quarter of Surgical Patients

Odds of pre-op opioid use up with age 31 to 40 years, tobacco use, illicit drug use, depression.

News Emergency Physicians Offer Recommendations for Identifying and Managing Opioid Use Disorder

Emergency Physicians Offer Recommendations for Identifying and Managing Opioid Use Disorder

American emergency medicine physicians have been taking measures to address the ongoing opioid crisis, which affects emergency departments throughout the country.

News Radiofrequency Denervation Efficacious in Treating Thoracic Zygapophyseal Joint Pain

Radiofrequency Denervation Efficacious in Treating Thoracic Zygapophyseal Joint Pain

Radiofrequency denervation, typically used to treat lumbar and cervical zygapophyseal joint pain, has shown efficacy in treating thoracic zygapophyseal joint pain.

Healthday Two-Thirds of Parents Report Their Child Has Had Headache

Two-Thirds of Parents Report Their Child Has Had Headache

Only 44 of parents would definitely go to ER if their child had headache that didn't improve with medication.

News Pain Societies Issue Guidelines on Use of Ketamine for the Management of Acute Pain

Pain Societies Issue Guidelines on Use of Ketamine for the Management of Acute Pain

Consensus guidelines regarding the use of ketamine for the management of acute pain have been approved.

Healthday US Surgeon General Urges More Americans to Carry Naloxone

US Surgeon General Urges More Americans to Carry Naloxone

Surgeon General Jerome M. Adams, M.D., M.P.H., has urged more Americans to carry naloxone, an FDA-approved medication that can be delivered via nasal mist or injection and can temporarily suspend the effects of opioid overdose.

Feature Stat Consult: Chronic Low Back Pain

Stat Consult: Chronic Low Back Pain

Chronic low back pain (LBP) defined as persistent or fluctuating musculoskeletal pain of lower back and lumbar spine lasting >3 months.

News FDA Upscheduling of Hydrocodone Places Burden on APRNs

FDA Upscheduling of Hydrocodone Places Burden on APRNs

A study assessing the impact of upscheduling of hydrocodone combined medications on APRN practices in Oklahoma revealed significant barriers to effective pain management.

News NKTR-181 for Chronic Lower Back Pain: SUMMIT-07 Results

NKTR-181 for Chronic Lower Back Pain: SUMMIT-07 Results

The phase 3 SUMMIT-07 trial assessed the safety, efficacy, and tolerability of a new mu-opioid receptor agonist analgesic in adults with moderate to severe chronic lower back pain.

News Recommendations for Perioperative Pain Management in Patients With Opioid Tolerance

Recommendations for Perioperative Pain Management in Patients With Opioid Tolerance

With the increasing number of patients presenting to surgery with opioid tolerance, clinicians should be familiar with their specific analgesic needs.

Healthday Cryoablation Efficacious for Cancer Pain, Review Finds

Cryoablation Efficacious for Cancer Pain, Review Finds

Cryoablation also cuts the need for opioids at 24 hours post-treatment and at three months

News PTSD Symptoms and the Acute Pain Response in Low-Income Women

PTSD Symptoms and the Acute Pain Response in Low-Income Women

Posttraumatic stress disorder symptoms may be associated with higher levels of acute pain and pain interference in low-income inner city women.

Healthday Recommendations Developed for Managing Postpartum Pain

Recommendations Developed for Managing Postpartum Pain

Impact of medications on mother-infant dyad should be considered, as many women breastfeed

News First-of-Its-Kind Migraine Drug Receives FDA Approval

First-of-Its-Kind Migraine Drug Receives FDA Approval

The efficacy of Aimovig was evaluated as a preventive treatment of episodic or chronic migraine in 3 randomized, double-blind, placebo-controlled studies: 2 studies in patients with episodic migraine (4-14 migraine days per month) and 1 study in patients with chronic migraine (≥15 headache days per month with ≥8 migraine days per month).

News Adding Chiropractic to Usual Care Beneficial for Low Back Pain

Adding Chiropractic to Usual Care Beneficial for Low Back Pain

Improvements in low back pain intensity and disability among active-duty military personnel

News Combining Spinal Manipulation and Exercise for Low Back Pain in Adolescents

Combining Spinal Manipulation and Exercise for Low Back Pain in Adolescents

A combination of self-care education, aerobic and strength-training exercise, and spinal manipulation therapy may provide greater pain relief and improved treatment satisfaction compared with exercise only in adolescents with low back pain.

News Helping to End Addiction: NIH Initiative Addresses Opioid Epidemic

Helping to End Addiction: NIH Initiative Addresses Opioid Epidemic

National Institutes of Health Director, Francis Collins, MD, PhD, announced on April 4, 2018 the launch of the Helping to End Addiction Long-Term Initiative.

Healthday Elder Abuse Not Associated With Risk of Chronic Pain

Elder Abuse Not Associated With Risk of Chronic Pain

Findings based on two-year follow-up of a large, community-dwelling cohort in Malaysia

News CBT vs Pain Education for Chronic Pain in Low-Income Clinics

CBT vs Pain Education for Chronic Pain in Low-Income Clinics

Group cognitive behavioral therapy and pain education may be more effective than usual care for improving pain and physical function in patients presenting with chronic pain at low-income clinics.

News Tai Chi May Be Therapeutic Option for Fibromyalgia

Tai Chi May Be Therapeutic Option for Fibromyalgia

Tai chi interventions may be more effective at treating fibromyalgia than aerobic exercise.

News FDA: Social Media Companies Are Not Doing Enough to Stop Illegal Opioid Sales

FDA: Social Media Companies Are Not Doing Enough to Stop Illegal Opioid Sales

FDA has called on social media companies and internet service providers to take a proactive approach in curbing online selling of opioids through their platforms.

Healthday Gluten-free diet associated with reduced neuropathy pain

Gluten-free diet associated with reduced neuropathy pain

Individuals with gluten neuropathy experienced less peripheral neuropathic pain when adhering to strict gluten-free diets.

News Transcutaneous electrical nerve stimulation may not alleviate lower back pain

Transcutaneous electrical nerve stimulation may not alleviate lower back pain

Transcutaneous electrical nerve stimulation may be ineffective in treating, relieving lower back pain when compared with other nerve stimulation therapies.

Two Minute Medicine

Talk therapy, modified for literacy level, helps ease chronic pain for disadvantaged populations

Both modified cognitive behavioral therapy and pain education interventions were associated with improved pain in patients with disadvantaged backgrounds.

Feature Assessing lidocaine efficacy for chronic pain management

Assessing lidocaine efficacy for chronic pain management

Intravenous, patch lidocaine might be effective in treating, preventing chronic pain.

Healthday FDA: Botanical drug kratom contains opioid compounds

FDA: Botanical drug kratom contains opioid compounds

Nearly all of kratom's major compounds bind to opioid receptors in the human brain, and 2 of the top 5 most prevalent compounds activate those receptors, FDA Commissioner Scott Gottlieb said in a statement. In addition, there have been 44 reported deaths associated with the use of kratom, often in combination with other substances, Gottlieb said.

Opinion Managing pain in primary care

Managing pain in primary care

A FNP reflects on his experiences working with pain management patients prescribed opioids.

News Brief intervention may be beneficial for adolescents with chronic pain

Brief intervention may be beneficial for adolescents with chronic pain

A combination of psychoeducation, cognitive-based therapy, visualization, and breathing exercises may represent a tolerable and readily accepted complementary therapeutic approach for adolescent patients with chronic pain.

Opinion Opioid use in middle-aged adults

Opioid use in middle-aged adults

Clinicians are in the unique position to educate and counsel middle-aged adults about their opioid use and influence strategies needed to provide effective pain control.

Blog Post When patients need services that don't exist

When patients need services that don't exist

It can be difficult to care for complex patients when they need services that do not exist.

Healthday Pain during IUD insertion reduced with lidocaine nerve block

Pain during IUD insertion reduced with lidocaine nerve block

A 1% paracervical nerve block may be useful for reducing patient-reported pain during IUD insertion.

Feature Opioids and naloxone for pain management

Opioids and naloxone for pain management

Co-prescribing naloxone and opioids in primary care is recommended for patients who have a high risk for opioid overdose.

Healthday Effects of cannabis treatment in adult patients with PTSD

Effects of cannabis treatment in adult patients with PTSD

Researchers found that cannabis may alleviate neuropathic pain, but is not associated with benefit for adults with PTSD.

Blog Post The role of prescription habits in the opioid epidemic

The role of prescription habits in the opioid epidemic

Current surgical and prescribing practices may have a hand in exacerbating the nation's burgeoning opioid epidemic.

Healthday Clinicians may be overprescribing gabapentinoids for pain

Clinicians may be overprescribing gabapentinoids for pain

Gabapentinoids may be overprescribed, in part as a response to the opioid epidemic.

News NASEM report outlines strategy to combat opioid epidemic

NASEM report outlines strategy to combat opioid epidemic

The FDA commissioned the report to provide an update on current evidence on research, care, and education in the pain field, and to identify actionable measures for the FDA to more adequately address the ongoing opioid epidemic.

News CDC: Opioid prescription rate remains high, inconsistent in the United States

CDC: Opioid prescription rate remains high, inconsistent in the United States

However, the number of opioids prescribed decreased between 2010 and 2015.

News Majority of opioid prescriptions are written for patients with mental disorders

Majority of opioid prescriptions are written for patients with mental disorders

Among the nearly 40 million Americans who have a mental health condition, about 19% use prescription opioids.

Healthday Opioids often prescribed to back pain patients with depression

Opioids often prescribed to back pain patients with depression

Researchers found that back pain patients are also more likely to get higher doses of opioids.

News Use of ketamine for pain management and treatment of depression

Use of ketamine for pain management and treatment of depression

Ketamine may alleviate depression, pain, and adverse effects associated with opioid treatment.

Healthday Opioid use before TKA causes less pain relief

Opioid use before TKA causes less pain relief

Clinicians should consider limiting pre-TKA opioid prescriptions to optimize the benefits of TKA.

News PA programs may need more focus on opioid prescribing practices

PA programs may need more focus on opioid prescribing practices

Many PA students and practicing PAs did not feel that their PA program adequately trained them to screen for opioid abuse.

News Corticosteroids for sore throat: a mixed bag of results

Corticosteroids for sore throat: a mixed bag of results

Oral corticosteroids could be an alternative symptomatic treatment for acute sore throat, which is a significant burden in primary care and a source of inappropriate antibiotic prescribing.

Healthday Mindfulness-based stress reduction may improve low back pain

Mindfulness-based stress reduction may improve low back pain

Mindfulness-based stress reduction was associated with short-term benefits for pain intensity and physical functioning.

Healthday Recommended dose of IV acetaminophen may be insufficient for multiple-trauma patients

Recommended dose of IV acetaminophen may be insufficient for multiple-trauma patients

Administration of acetaminophen at the recommended dosage yields serum concentrations below 10 µg/mL due to increased elimination.

Healthday Surgery patients may have higher risk of opioid addiction

Surgery patients may have higher risk of opioid addiction

Researchers found that some surgery patients may face a higher risk of becoming dependent on opioids.

News CDC's opioid guideline prompts clinician concerns

CDC's opioid guideline prompts clinician concerns

The recently released CDC guidelines on opioid prescribing remain a topic of debate.

News Radiofrequency treatment effective for refractory chronic joint pain

Radiofrequency treatment effective for refractory chronic joint pain

Radiofrequency treatment is an effective option for treating refractory chronic knee, hip, and shoulder joint pain.

News Perioperative care for acute pain management

Perioperative care for acute pain management

Patients with chronic pain who are hospitalized have a higher risk of morbidity and mortality, longer lengths of stay, and more frequent readmissions than patients without chronic pain.

Healthday Glucocorticoid injection offers relief for lower back pain

Glucocorticoid injection offers relief for lower back pain

At 1 month after the intervention, the percentage of responders was higher in the GC IDI group than the control group.

News Opioid and benzodiazepine combination use significantly increases overdose risk

Opioid and benzodiazepine combination use significantly increases overdose risk

The drug combination significantly contributes to the overall population risk of opioid overdose.

News Opioids for chronic pain: a new clinical guideline from the VA and Department of Defense

Opioids for chronic pain: a new clinical guideline from the VA and Department of Defense

The Veterans Administration and Department of Defense issue a clinical practice guideline regarding opioid therapy for chronic pain in veterans.

News Noninvasive treatment for low back pain: a new clinical guideline from ACP

Noninvasive treatment for low back pain: a new clinical guideline from ACP

The ACP has released 3 recommendations for the treatment of patients with acute, subacute, and chronic low back pain.

Healthday Intravenous lidocaine safe for reducing pain in ICU patients

Intravenous lidocaine safe for reducing pain in ICU patients

Intravenous lidocaine is safe for reducing pain in patients in the ICU with varying degrees of organ dysfunction.

News American Chronic Pain Association issues toolkit for clinicians

American Chronic Pain Association issues toolkit for clinicians

The toolkit will provide healthcare professionals with adequate tools to manage their patients' pain.

Healthday Increased naloxone prices could affect rates of opioid-related mortality

Increased naloxone prices could affect rates of opioid-related mortality

Researchers identify strategies that could ensure access to naloxone.

Healthday Virtual reality game may help relieve phantom limb pain

Virtual reality game may help relieve phantom limb pain

Recent data suggests that a virtual reality game could reduce pain by as much as one-half.

News Outpatient program may be effective for pain self-management

Outpatient program may be effective for pain self-management

A program based on cognitive behavioral therapy and physical exercise could improve pain self-management in patients with complex pain.

News FDA approves new drug for postmenopausal pain during sex

FDA approves new drug for postmenopausal pain during sex

Intrarosa provides an additional treatment option for women with dyspareunia caused by vulvar and vaginal atrophy.

Blog Post Lidocaine patches as an alternative pain solution

Lidocaine patches as an alternative pain solution

Lidocaine patches may be effective for patients who are in pain but are looking to avoid drugs that could be addictive.

Healthday Quality improvement intervention helps pain management for seniors in the ER

Quality improvement intervention helps pain management for seniors in the ER

Researchers conducted an examination in patients over 65 years with moderate-to-severe pain in an academic emergency department.

Healthday More than half of US citizens have a chronic health condition

More than half of US citizens have a chronic health condition

Conditions such as chronic disease, mental illness, or substance abuse commonly overlap with each other and with poverty, which contributes to poor health.

News Barriers remain in patients' acceptance of naloxone use in primary care

Barriers remain in patients' acceptance of naloxone use in primary care

Patients would like more thorough conversations with their primary care physician over the use of naloxone.

News Comparing treatments for pediatric migraines

Comparing treatments for pediatric migraines

No significant differences were observed among treatments for pediatric migraines.

Healthday Treatment costs lower with pregabalin vs gabapentin for peripheral neuropathic pain

Treatment costs lower with pregabalin vs gabapentin for peripheral neuropathic pain

The average total cost was lower for pregabalin treatment due to lower use of concomitant medications, fewer primary care visits, and fewer sick days.

Healthday Pain relief during labor may lower risk of postpartum depression

Pain relief during labor may lower risk of postpartum depression

Women who received epidural pain relief during labor had lower scores on the Edinburgh Postnatal Depression Scale.

Healthday Placebo treatments may help patients with chronic lower back pain

Placebo treatments may help patients with chronic lower back pain

Patients who knew they were taking a placebo pill still experienced less lower back pain.

News Complementary health approaches frequently used for musculoskeletal pain disorders

Complementary health approaches frequently used for musculoskeletal pain disorders

Data from the CDC's National Health Statistics Reports show that more than half of adults in the United States have a musculoskeletal pain disorder.

News Nonmedical use of prescription opioids in adolescence leads to substance use disorder symptoms in adulthood

Nonmedical use of prescription opioids in adolescence leads to substance use disorder symptoms in adulthood

Using medical or nonmedical prescribed opioids in adolescence may lead to alcohol, drug, and mental health disorders in adulthood.

Feature Genetic vascular anomaly

Genetic vascular anomaly

A young Caucasian woman presented with complaints of years regarding pain in her feet but did not know the cause.

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