Generic Name and Formulations:
Mesalamine 250mg, 500mg; controlled-rel caps.
Shire US, Inc.
Indications for PENTASA:
Mildly-to-moderately active ulcerative colitis.
Swallow whole; may open caps and sprinkle entire contents onto applesauce or yogurt, consume immediately. 1g four times daily for up to 8 weeks.
Discontinue if acute intolerance syndrome is suspected. Atopic dermatitis or eczema: may have more severe photosensitivity reactions. Renal disease; monitor SCr, BUN, proteinuria. Hepatic impairment. Pregnancy (Cat.B). Nursing mothers.
May interfere with urinary normetanephrine test by liquid chromatography; consider alternative assay.
Diarrhea, headache, nausea, abdominal pain, dyspepsia, vomiting, rash; nephrotoxicity.
Caps 250mg—240; 500mg—120