Screening for asymptomatic CAD may not reduce cardiac events in diabetes patients
Level 2: Mid-level evidence Patients with diabetes are known to be at increased risk for coronary artery disease (CAD) as well as silent ischemia. The Detection of Ischemia in Asymptomatic Diabetics (DIAD) trial evaluated using adenosine-stress radionuclide myocardial perfusion imaging to screen 1,123 patients with diabetes who had no cardiovascular symptoms (JAMA. 2009;301:1547-1555). Results showed…