GP100 vaccine with IL-2 improved melanoma outcomes
New data indicate that combining GP100 with interleukin-2 increased clinical response, delayed recurrence and may improve survival among patients with advanced melanoma
Diagnosis & Disease Information
Hydroxyurea reduces pain in young sickle-cell disease patients
BABY-HUG trial results indicate that hydroxyurea significantly reduces pain events in children with sickle-cell disease, and was also associated with reduced gastroenteritis, acute chest syndrome, transfusions and hospitalizations.
Prunes more effective for constipation than psyllium?
Until recently, there has been little direct evidence to evaluate the efficacy of prunes as a dietary treatment or to compare prunes with other treatments for constipation.
Bactericide fights C. difficile infection
Fidaxomicin was noninferior to vancomycin among adults with Clostridium difficile-associated diarrhea in two randomized, double blind trials.
Dextranomer gel injections for fecal incontinence
Local injections to narrow the anal canal reduced fecal incontinence by 25% at one-year follow-up, data from recent clinical trials indicate.
COPD therapy now available in pill form
Daliresp is a selective phosphodiesterase 4 inhibitor that reduces risk for chronic obstructive pulmonary disease exacerbations in severely effected patients with COPD that have chronic bronchitis and a history of exacerbations.
Stat Consult: Breastfeeding
A quick review of breastfeeding recommendations, including timelines for infant weaning, guidelines for appropriate supplementation and contraindications.
The 100-day cough: clinicians be(a)ware
Only 5.9% of eligible candidates receive the recommended pertussis booster vaccine, and the disease remains one of the leading causes of vaccine-preventable deaths worldwide.
Antibiotics have no effect on oral contraceptives
While it is true that lower serum ethinyl estradiol and progestin levels have been found in women using combination OCs and antibiotics, these women remain well within the therapeutic window.
Remember to HALT SLIPS in older patients
A clinician offers a useful mnemonic device to help prevent falls in older patients.
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