December 01, 2009 Archives - Clinical Advisor

Print Issue: December 01, 2009

Ultrapotent topical corticosteroids are the treatment of choice for vulvar lichen sclerosus patients

Treatment of vulvar lichen sclerosus

My patient was diagnosed with lichen sclerosus on vulvar biopsy. What is the recommended treatment, and how long should it be used? If the patient is asymptomatic, must therapy be implemented at all?

Prediction rule identifies children at low risk after suffering minor head trauma

Level 1: Likely reliable evidence CT is often performed on children with head trauma to diagnose clinically important traumatic brain injuries. Attempts have been made to develop criteria that might safely avoid unnecessary procedures. The Pediatric Emergency Care Applied Research Network (PECARN) study has now developed a prediction rule that identifies children who are at…

IM vaccine may be more effective than intranasal vaccine for seasonal flu in healthy adults

Level 2: Mid-level evidence IM and intranasal seasonal influenza vaccines were compared with each other and with placebo in a randomized trial involving 1,952 healthy adults during the 2007-2008 influenza season (N Engl J Med. 2009;361:1260-1267; available at content.nejm.org/cgi/content/full/361/13/1260, accessed November 9, 2009). The rate of laboratory-confirmed symptomatic influenza was 6.1% overall, with lowest incidence…

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