December 14, 2007 Archives - Page 3 of 6 - Clinical Advisor

Print Issue: December 14, 2007

Anticoagulation after hip surgery

Are fondaparinux (Arixtra) injections preferable to warfarin (Coumadin) for management of anticoagulation in postoperative hip-fracture patients and those recovering from joint replacement surgery? Warfarin works just fine and prevents deep venous thrombosis (DVT) and pulmonary embolism for prolonged periods of time.—Patricia White, ARNP, Vero Beach, Fla. I was unable to find a head-to-head trial in…

PSYCHOTHERAPEUTIC SUPPORT APPEARS TO INCREASE POST-GI CANCER SURVIVAL

Level 2: Mid-level evidence The efficacy of psychotherapeutic support was evaluated in a randomized trial of 271 patients having surgery for cancer of the liver/gallbladder, pancreas, colon/rectum, esophagus, or stomach (J Clin Oncol. 2007;25:2702-2708). Patients were randomized to support provided by psychotherapists during both pre- and postoperative hospital stay. Psychotherapists provided emotional and cognitive support…

Reducing caffeine use in late pregnancy does not affect birth weight or length of gestation…

Level 1: Likely reliable evidence …BUT AVOIDING HIGH CAFFEINE DOSES IS GENERALLY RECOMMENDED Level 2: Mid-level evidence A randomized trial evaluated the effect of caffeine in 1,207 pregnant women who drank at least three cups of coffee per day (BMJ. 2007;334:409; full-text available online free of charge at: www.bmj.com/cgi/, accessed November 12, 2007). Women were…

INHALED STEROIDS REDUCE COPD

Level 1: Likely reliable evidence A systematic Cochrane review evaluated 47 randomized placebo-controlled trials of inhaled corticosteroids (ICS) involving 13,139 patients with stable chronic obstructive pulmonary disease (COPD) (Cochrane Database Syst Rev. 2007[2]:CD002991). Most trials were of good quality. Comparing ICS vs. placebo, there were no significant differences in mortality: 8% vs. 8% in nine…

CALCIUM APPEARS TO LOWER CANCER RISK IN WOMEN

Level 2: Mid-level evidence The risk of cancer was evaluated as a secondary outcome in a randomized trial of 1,024 healthy, community-dwelling, postmenopausal women older than 55 years in rural Nebraska (Am J Clin Nutr. 2007;85:1586-1591). The subjects were randomly assigned to receive 1,400-1,500 mg of supplemental calcium/day alone, supplemental calcium plus 1,100 IU vitamin…

Reducing the risk of gynecologic cancers

Cervical, ovarian, and uterine cancer are potentially deadly. Follow these prevention and detection strategies to reduce their toll. One of every three women in the United States will develop cancer at some point, according to the American Cancer Society (ACS).1 Of the 10 most common malignancies, three are gynecologic—cervical, ovarian, and uterine. By incorporating prevention…

Next post in Features