February 01, 2009 Archives - Clinical Advisor

Print Issue: February 01, 2009

Skin tag removal

What is the best way to minimize scarring in the removal of skin tags? I find that cryotherapy results in…

Switch cholesterol therapy?

I have a patient with severe coronary artery disease (he has already had quadruple bypass) and multiple risk factors for metabolic syndrome. His LDL goal is being met with ezetimibe 10 mg/simvastatin 80 mg (Vytorin 10/80). Given the results of the Ezetimibe and Simvastatin in Hypercholesterolemia Enhances Atherosclerosis Regression (ENHANCE) trial showing that Vytorin lowers…

Rosuvastatin lowers mortality and cardiovascular events in patients with high CRP, normal cholesterol

Level 1: Likely reliable evidenceThe Justification for the Use of Statins in Primary Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER) studied the use of rosuvastatin (Crestor) for prevention of cardiovascular events in patients with normal cholesterol levels but elevated C-reactive protein (CRP) levels (N Engl J Med. 2008;359:2195-2207). A total of 17,802 patients (11,001 men…

Hyperhidrosis

Description • Excessive perspiration occurring in either specific focal locations or in generalized pattern over the body ICD-9 codes • 705.2 focal hyperhidrosis     — 705.21 primary focal hyperhidrosis     — 705.22 secondary focal hyperhidrosis• 780.8 generalized hyperhidrosis Types • Focal hyperhidrosis (also called “primary,”  “idiopathic,” or “essential” hyperhidrosis)    — Palmar-plantar hyperhidrosis: excess sweating of palms of hands and soles of feet     — Isolated axillary hyperhidrosis: excess sweating of…

St. John’s wort may be as effective as standard antidepressants — and more tolerable — for major depression

Level 1: Likely reliable evidenceA recent Cochrane systematic review evaluated the efficacy and safety of St. John’s wort extracts for the treatment of major depression (Cochrane Database Syst Rev. 2008[4]:CD000448). The review included 29 randomized trials comparing St. John’s wort with placebo (11 trials), standard antidepressants (12 trials), or both (six trials) in a total…

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