January 30, 2008 Archives - Page 12 of 12 - Clinical Advisor

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Doribax- New antibiotic treats abdominal infections

Company: Ortho-McNeil Pharmacologic class: Antibiotic (carbapenem) Active ingredient: Doripenem (as monohydrate) 500 mg/vial; powder; for IV infusion after constitution and dilution; preservative-free. Continue Reading Indications: Susceptible complicated intra-abdominal and complicated UTIs (including pyelonephritis). Pharmacology: Doripenem is a carbapenem antibiotic that has shown to be active against aerobic and anaerobic gram-negative and gram-positive bacteria. It inactivates…

Two yellow-crusted eruptions

CASE #1 A 40-year-old man with a long history of atopic dermatitis and generalized lichen simplex chronicus noted rapid development of yellow-crusted patches superimposed on his atopic dermatitis. Microscopic examination showed gram-positive bacteria in clusters. A Tzanck smear and viral culture (read out days later) was negative. The patient stated that similar albeit more localized…

Persistent warty lesions on the trunk and inner thigh

A 59-year-old Hispanic male complained of persistent extensive brown warty lesions that had first appeared on his left lateral trunk and left inner thigh 12 years ago. Occasionally, the lesions would burn or itch, but they were otherwise asymptomatic. He reported no history of birthmarks, vesicular or inflamed appearance of the area, or similarly affected…

Hyperkeratotic plaques in a returning soldier

A 36-year-old man had three well-circumscribed, ulcerated, hyperkeratotic plaques on his left arm. He reported noticing a small papule approximately two months earlier. The papule was asymptomatic, but it continued to enlarge and develop over time into an ulcerated plaque. Two additional papules also developed into plaques. The rest of his physical exam was unremarkable.…

MRSA: Not a new crisis

We frequently hear prominent people in the community complain about the effect the lay media have on society. I often question the degree to which the media influence the public’s perception of a given issue. Over the past few months, the media have turned their attention toward the very serious problem of community-acquired methicillin-resistant Staphylococcus…

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