Print Issue: July 02, 2009

Computer rendering of normal digestive tract (f. left) to deformed shape (f. right)

Use of antidepressants or psychotherapy may reduce irritable bowel symptoms

Level 2: Mid-level evidenceIrritable bowel syndrome (IBS) is a chronic disorder that causes abdominal pain and is often associated with psychological distress. A recent systematic review of 32 randomized trials analyzed the efficacy of various antidepressants and psychotherapies in the treatment of IBS (Gut. 2009;58:367-378). There was a significant decrease in the relative risk (RR)…

Clumps of methicillin-resistant Staphylococcus aureus bacteria

Necrotizing pneumonia linked to CA-MRSA

Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) is responsible for an increasing number of pneumonia cases among otherwise healthy, younger patients

Myeloma replaces cells in the marrow, leaving the appearance of holes in the bone

New agents for myeloma

What is the current role of interferon and rituximab in myeloma therapy? —K. KONSTANTOPOULOS, MD, Athens Interferon-α (IFN-α) treatment has been employed in many studies. Two separate meta-analyses of the clinical data have been published (Br J Haematol. 2001;113:1020-1034 and Ann Oncol. 2000; 11:1427-1436). Both analyses revealed a modest benefit in progression-free survival; only one…

Hyperglycemia after coronary bypass

What do you recommend for treatment of hyperglycemia in patients who have undergone coronary artery bypass? —JEFFREY ARBOUR, PA-C, Saline, Mich Clinical evidence supports the use of intensive gylcemic control. Insulin drip therapy to maintain a blood glucose level of 80-110 mg/dL reduces morbidity and mortality. Initiation of a specific protocol for an insulin drip…

Substance-abuse screening package

The National Institute on Drug Abuse (NIDA) has launched NIDAMED, a collection of tools and resources to help primary-care clinicians screen patients for tobacco, alcohol, and illicit drug use.

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