Print Issue: November 03, 2006

KNEELING MAY BE MORE COMFORTABLE THAN SITTING FOR WOMEN DURING DELIVERY

Level 2: Mid-level evidence Pregnant women should be encouraged to give birth in the position they find most comfortable, as no clear benefits or risks of various delivery positions have been demonstrated in methodologically stringent trials. This conclusion is based on a systematic review of 19 trials of variable quality with 5,764 women (Cochrane Database…

COGNITIVE BEHAVIORAL THERAPY IMPROVES CHRONIC TMJ

Level 1: Likely reliable evidence Cognitive behavioral therapy (CBT) for chronic temporomandibular joint (TMJ) disorder reduces pain and depression at one year based on a recent randomized trial (Pain. 2006;121:181-194). Adults with chronic TMJ and facial pain-related disability (N = 156) were randomized to CBT vs. education/attention control for four sessions every other week over…

MOBILE-PHONE SIGNALS DO NOT INDUCE HEADACHE

Level 1: Likely reliable evidence The effect of mobile-phone signals on headache was evaluated in a study of 71 “sensitive” participants aged 18-75 years who reported frequent headachelike symptoms occurring within 20 minutes of using a global system for communication (GSM) mobile phone. They were compared with 60 “controls” who had no such symptoms (BMJ.…

GALANTAMINE DOES NOT APPEAR TO IMPROVE GOAL ATTAINMENT IN ALZHEIMER’S DISEASE

Level 2: Mid-level evidence Galantamine (Razadyne, previously Reminyl) is used to treat mild-to-moderate Alzheimer’s disease (AD). A previously published systematic review of 10 randomized, double-blind, placebo-controlled trials concluded that galantamine 16 mg daily improved global and cognitive symptoms for at least six months in mild-to-moderate AD (Cochrane Database Syst Rev. 2006;[1]:CD001747). Trials lasted at least…

Glumetza- Once-daily dosing effective for type 2 diabetes control

Companies: Depomed and King Pharmacologic class: Antihyperglycemic (biguanide) Active ingredient: Metformin HCl 500 mg; extended-release tabs.Continue Reading Indication: Adjunct to diet and exercise in type 2 diabetes as monotherapy, or with a sulfonylurea or insulin. Pharmacology: Glumetza extended-release tablets are designed to deliver metformin HCl to the upper GI tract, which may reduce GI side…

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