Level 2: Mid-level evidence Pregnant women should be encouraged to give birth in the position they find most comfortable, as no clear benefits or risks of various delivery positions have been demonstrated in methodologically stringent trials. This conclusion is based on a systematic review of 19 trials of variable quality with 5,764 women (Cochrane Database…
Level 1: Likely reliable evidence Cognitive behavioral therapy (CBT) for chronic temporomandibular joint (TMJ) disorder reduces pain and depression at one year based on a recent randomized trial (Pain. 2006;121:181-194). Adults with chronic TMJ and facial pain-related disability (N = 156) were randomized to CBT vs. education/attention control for four sessions every other week over…
Level 1: Likely reliable evidence The effect of mobile-phone signals on headache was evaluated in a study of 71 “sensitive” participants aged 18-75 years who reported frequent headachelike symptoms occurring within 20 minutes of using a global system for communication (GSM) mobile phone. They were compared with 60 “controls” who had no such symptoms (BMJ.…
Level 2: Mid-level evidence Galantamine (Razadyne, previously Reminyl) is used to treat mild-to-moderate Alzheimer’s disease (AD). A previously published systematic review of 10 randomized, double-blind, placebo-controlled trials concluded that galantamine 16 mg daily improved global and cognitive symptoms for at least six months in mild-to-moderate AD (Cochrane Database Syst Rev. 2006;[1]:CD001747). Trials lasted at least…
Are decisions to clear patients for surgery within the scope of practice for primary-care clinicians?
Companies: Depomed and King Pharmacologic class: Antihyperglycemic (biguanide) Active ingredient: Metformin HCl 500 mg; extended-release tabs. Indication: Adjunct to diet and exercise in type 2 diabetes as monotherapy, or with a sulfonylurea or insulin.Continue Reading Pharmacology: Glumetza extended-release tablets are designed to deliver metformin HCl to the upper GI tract, which may reduce GI side…
