Diagnosis & Disease Information

ROSIGLITAZONE AND METFORMIN MAY BE MORE EFFECTIVE FOR GLYCEMIC CONTROL

Level 2: Mid-level evidence Before rosiglitazone was linked to increases in heart disease, researchers for A Diabetes Outcome Progression Trial (ADOPT) compared the efficacy of rosiglitazone (Avandia) vs. metformin (Glucophage, Fortamet) vs. glyburide (Diabeta, Glynase, Micronase) for glycemic control in 4,360 patients aged 30-75 years with type 2 diabetes (N Engl J Med. 2006;355:2427-2443). Patients…

CDC kicks off preteen vaccine campaign

Have an unusually large number of parents been inquiring lately about vaccinations for their 11- and 12-year-old children? Credit a recently launched CDC campaign. The agency is promoting checkups to implement its current recommendations for three preteen vaccines: • MCV4, which protects against meningitis and its complications; • Tdap, a booster against tetanus, diphtheria, and…

Dementia and parkinsonism tied to surgery

Women who have had ovarian surgery before menopause are much more likely to develop dementia or parkinsonism years later without estrogen therapy, according to a pair of observational analyses. “It’s possible that estrogen has a protective effect on the brain and that a lack of estrogen due to ovary removal may increase a woman’s risk”…

High BP goes undetected in most kids

Clinicians are failing to identify most cases of hypertension in children aged 3-18 years, a large study shows.Researchers at Case Western Reserve University in Cleveland assessed the records of 14,200 youngsters in this age group who had been examined at least three times for well-child care between June 1999 and September 2006 in outpatient clinics…

Multiple BMD test sites assess fracture risk

Bone mineral density (BMD) of the total hip is a better predictor of most osteoporotic fractures than either the lumbar spine or particular hip components, Canadian researchers have found. However, lumbar measurements are best for targeting spinal fractures. This study used a database of 16,505 women aged 50 years or older when they underwent baseline…

Coffee may cut diabetes risk

Moderate coffee consumption is associated with a reduced risk of having diabetes, according to researchers in Greece. The findings come from a study of 500 men and 437 women (aged 65-100 years) from Cyprus, Crete, and other Mediterranean islands. Of the 937 subjects, 84% of them reported drinking coffee. All were asked about the frequency…

Asthmatic kids who miss meds

Parental fears about side effects are keeping preventive medications from most asthmatic children, a recent survey finds. Although almost three out of four parents strongly agreed that they trusted the doctor’s judgment, only 14% said they completely adhered to prescribed regimens. That’s because many parents believe the medications were either not essential or were even…

Another risk factor turns up for diabetes

Diabetes has long been recognized by clinicians as a risk factor for heart disease. Now a study shows the association works both ways: MIs pose a significant risk for developing diabetes or impaired fasting glucose (IFG), a prediabetic condition. In the study, an American-Italian team analyzed data involving 8,291 patients collected during an earlier randomized…

HMO balks at paying for overtime

A physician assistant finds that sometimes being considered a “professional” can be a costly label. After three years as a physician assistant at a large HMO in the Southwest, Ms. P discovered that she was not being paid time-and-a-half overtime rates when she worked more than 40 hours in a week. She had never thought…

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