Print Issue: October 09, 2007

Endometrin- Progesterone for embryo implantation

Company: Ferring Pharmacologic class: Progestin Active ingredient: Progesterone 100 mg; vaginal insert.Continue Reading Indication: To support embryo implantation and early pregnancy by supplementation of corpus luteal function as part of an Assisted Reproductive Technology treatment program for infertile women. Pharmacology: Progesterone supplementation is used to provide support for the luteal phase, preparing the endometrium for…

Neupro- Early-stage Parkinson’s treatment

Companies: UCB and Schwarz Pharma Pharmacologic class: Dopamine agonist (non-ergot) Active ingredient: Rotigotine 2 mg/24 hours, 4 mg/24 hours, 6 mg/24 hours; transdermal patch; contains sulfites. Continue Reading Indication: Treatment of patients with early-stage idiopathic Parkinson’s disease who are not receiving concomitant l-dopa. Pharmacology: Neupro is a transdermal patch containing rotigotine, a D3/D2/D1 dopamine agonist.…

AzaSite- Topical solution for bacterial conjunctivitis

Company: Inspire Pharmacologic class: Antibiotic (macrolide) Active ingredient: Azithromycin 1%; ophthalmic solution; contains benzalkonium chloride. Continue Reading Indication: Susceptible bacterial conjunctivitis. Pharmacology: AzaSite is an ophthalmic solution formulation of the macrolide antibiotic azithromycin, for the topical treatment of bacterial conjunctivitis caused by CDC coryneform group G, Hemophilus influenzae, Staphylococcus aureus, Streptococcus mitis group, and Streptococcus…

Armloads of pigmentation

<img src="https://www.clinicaladvisor.com/wp-content/uploads/sites/11/2018/12/dermlook1007case1.gif" CASE #1 A 25-year-old Mexican woman presented with ashy brown-blue macules that had developed on her arms and upper torso after puberty. She did not know whether the macules had ever been erythematous or had an erythematous border. Negative rapid plasma reagin testing ruled out late-stage pinta. Biopsy revealed a sparse lymphocytic dermal…

Tender ulcerated pustular plaques on the dorsal hand

<img src="https://www.clinicaladvisor.com/wp-content/uploads/sites/11/2018/12/dc1007case2.gif" A 45-year-old white man presented to the emergency department (ED) with a three-week history of large tender plaques that had started as pustules on the dorsal hand. The plaques had ruptured and were draining purulent fluid. The man also reported significant malaise and low-grade fevers. A 72-hour trial of cephalexin yielded no improvement,…

Pruritic swelling in a young woman’s colorful tattoo

<img src="https://www.clinicaladvisor.com/wp-content/uploads/sites/11/2018/12/dc1007case1.gif" A fit and healthy 28-year-old woman presented with an eight-week history of swelling, erythema, and pruritus arising from a defined area of her back. The affected region corresponded exactly to the red pigmented areas of the tattoo she had acquired 18 months before. The patient had previously consulted her primary-care clinician, who had…

Become a health-care voter

John was 50 years old. He had hypertension, diabetes, and a third and equally insidious condition—no health insurance. Although John had found sporadic medical care in emergency departments and “sliding-scale” clinics over the years, decades of spotty management had irreversibly damaged his kidneys and placed him on the list for hemodialysis. The good news is…

Multiple complaints unresolved after

Surgery eliminated her cardiac symptoms, but the elderly patient continued to bring a list of complaints to every visit. Mrs. W, 84 years old, was referred for ongoing care after successful cardiac bypass. Her history was significant for CAD, hypertension, diverticulosis with a GI bleed one year earlier, osteoporosis, osteoarthritis, irritable bowel syndrome, and gastroesophageal…

Coenzyme Q10

Coenzyme Q10 (CoQ10) is a naturally occurring fat-soluble organic compound with a structure very similar to that of vitamins E and K.1 It is one of a multitude of compounds that function either as coenzymes or as chemicals essential to a chain of enzyme function. CoQ10 is vital for mitochondrial function, which controls the production…

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