Pulmonology News Archive

New long-acting bronchodilator use linked to CV risk in COPD patients

Use of long-acting bronchodilators is linked to cardiovascular risks in patients with COPD.

Obesity in preschoolers leads to exacerbated asthma

Overweight/obese preschools have greater asthma symptoms than normal-weight children when untreated.

Air pollution increases mortality risk in older adults

Exposure to surrounding air pollutants and warm season ozone are linked to increased risk of death.

FDA removes Boxed Warning from select asthma, COPD medications

New evidence regarding safety is spurring the US FDA to remove a Boxed Warning from certain inhaled medications used to treat asthma and COPD.

Steady rate of marijuana use associated with decline in cigarette, alcohol use in adolescents

Adolescent marijuana prevalence today would be at or near record highs if cigarette use had not declined since 2005.

Proposed pneumonia vaccine provides universal pneumococcal disease prevention

A pneumonia vaccine under development provides the most comprehensive coverage to date and alleviates antimicrobial concerns.

Treatment guidelines updated for coughing associated with common cold

There has been little change in the treatment recommendations for cough due to the common cold since publication of guidelines in 2006.

Combination antibiotic treatment beneficial for community-acquired pneumonia

A combination antibiotic regimen with a macrolide was shown to improve short- and long-term outcomes in patients with community-acquired pneumonia.

Clinical tool developed to determine pediatric community-acquired pneumonia severity

Researchers developed a clinical tool to predict prolonged hospital stays in patients with pediatric community-acquired pneumonia.

Half of adults with work-related asthma receive pneumococcal vaccination

The researchers found that 42% of the estimated 12 million ever-employed adults with current asthma had received a pneumococcal vaccine.

GERD may be associated with long-term risk of pneumonia

Incidence of pneumonia was higher among patients with GERD compared with matched controls.

Once-daily single-inhaler triple therapy better for lung function in COPD

Results support the benefits of single-inhaler triple therapy compared with inhaled corticosteroid/long-acting β2-agonist therapy in patients with advanced COPD.

Smoking may be a risk factor for psoriasis

Researchers observed a positive correlation between the amount and duration of smoking and the occurrence of psoriasis.

Asthma associated with later development of inflammatory bowel disease

Asthma was associated with Crohn's disease and with early- and late-onset ulcerative colitis.

Sepsis, pneumonia lead to increased risk of cardiovascular disease in men

Men who are admitted to the hospital with a serious infection may have an increased risk of cardiovascular disease in the years immediately following the infection.

Hypoxia, increased work of breathing outweigh tachypnea, auscultatory findings in diagnosing pneumonia

No single clinical observation reliably differentiates pneumonia from other causes of respiratory illness in children.

Vitamin B supplements not chemopreventive for lung cancer

Vitamin B supplements are not chemopreventive and may increase cancer risk in men.

Oral corticosteroids not effective for lower respiratory tract infection

No significant effects were found from oral corticosteroid use for acute lower respiratory tract infection in adults without asthma.

Tips for avoiding pneumonia in patients with COPD

The COPD Foundation has released tips for patients with COPD to avoid pneumonia and exacerbations.

Occupational pesticide exposure linked to fixed airflow obstruction and chronic bronchitis

Results show that exposure to pesticides and herbicides is associated with fixed airflow obstruction and chronic bronchitis.

Treating acute COPD exacerbations with prednisone and doxycycline

Researchers found that doxycycline plus prednisone did not prolong the time between exacerbations in patients with COPD.

VZV-related community-acquired pneumonia linked to morbidity, mortality

The hospital and ICU mortality rates of critically ill patients with VZV-CAP were 24% and 17%, respectively.

Sleep disorders may increase risk for Alzheimer's disease

Obstructive sleep apnea and sleep-disordered breathing are associated with amyloid deposition.

Chest CT provides additional insight in COPD assessment

A chest CT can provide additional information on comorbidities, including coronary artery disease and osteoporosis.

WHO updates Essential Medicines List, recommendations for antibiotics

The update includes 30 new medicines for adults and 25 for children and groups antibiotics into 3 distinct categories.

Higher childhood intelligence linked to lower mortality risk

Researchers sought to examine the link between intelligence scores during childhood and leading causes of death during the life course.

Social support boosts rehabilitation in adult COPD patients

Patients are more likely to exercise and participate in pulmonary rehabilitation if they live with others and have a caregiver.

Cardiovascular and cerebrovascular risk may decrease with LABA/LAMA in COPD

LABA/LAMA is associated with a similar or lower risk of cardiovascular and cerebrovascular adverse events compared to treatment with LABA/inhaled corticosteroid.

Opioid use increases risk of cardiac events in older COPD patients

Users of opioid-only agents had significantly increased rates of emergency room visits and hospitalizations for ischemic heart disease and IHD-related mortality.

Beta-blocker therapy may reduce exacerbations in moderate-to-severe COPD

Cardiac geometry demonstrated by non-contrast computerized tomography scan can predict which patients will respond to β-blocker therapy with a reduction in exacerbation frequency.

Chlorhexidine oral rinse solution ineffective for aspiration pneumonia

Study findings suggest that nursing home residents should receive more guidance in using strategies to prevent aspiration during eating and drinking.

Home noninvasive ventilation with oxygen therapy effective for COPD and hypercapnia

Adding home noninvasive ventilation to home oxygen therapy was effective in patients with persistent hypercapnia following an acute exacerbation of COPD.

NIH creates COPD National Action Plan

The national action plan released by the NHLBI aims to reduce the burden of COPD through collaboration with federal agencies, patients, advocates, and researchers.

Extrafine triple therapy may reduce rate of COPD exacerbations

The TRINITY study found that triple therapy significantly reduced the rate of COPD exacerbations.

Mortality decreasing for patients hospitalized with COPD in the US

The annual number of patients who died from COPD while in the hospital decreased 62% from 2005 to 2014.

First antibiotic prescription ineffective in 25% of pneumonia cases

About 1 in 4 adult patients with pneumonia do not respond to initial prescription of antibiotic treatment.

Surgical pulmonary embolectomy for thrombus distribution is feasible, effective

Surgical pulmonary embolectomy for peripheral distribution of thrombus demonstrated positive outcomes in patients with either CPE or PPE.

Eosinophilic COPD vs COPD with asthma: comparing clinical characteristics

Distinct differences occur between eosinophilic COPD and COPD patients with asthma.

Pulmonary hyperinflation linked to larger pulmonary artery in COPD

Increased residual volume is associated with a larger pulmonary artery in patients with COPD.

Asthma attacks can be triggered by thunderstorms

A 2016 thunderstorm asthma outbreak in Australia occurred when high grass pollen concentrations were dispersed by strong winds.

Inhaled corticosteroid use linked to increased pneumonia risk in asthma patients

The use of inhaled corticosteroids is associated with an increased risk of pneumonia in asthma patients.

Some antidiabetic agents may increase pneumonia risk in type 2 diabetes

Compared with current use of metformin + sulfonylurea, the use of thiazolidinediones + metformin was associated with an increased risk of community-acquired pneumonia.

Benzodiazepines may increase risk of pneumonia in Alzheimer disease

Clinicians should consider risk of pneumonia when weighing the benefits and risks of benzodiazepines in patients with Alzheimer disease.

Neutrophil-to-lymphocyte ratio may predict mortality in community-acquired pneumonia

All participants with a neutrophil-to-lymphocyte ratio greater than 28.3 died within 30 days.

Managing elderly patients with COPD through empowerment

Use of the empowerment approach is necessary for health promotion in older patients with COPD, but little attention has been paid to the dimensions of empowerment in COPD management.

Utibron Neohaler available for long-term treatment of COPD

Utibron Neohaler inhalation powder is indicated for the long-term maintenance treatment of airflow obstruction in patients with COPD.

Antidepressant serum levels may be lower in cigarette smokers

Serum concentration levels of several antidepressants were lower in cigarette smokers compared with nonsmokers.

Managing COPD exacerbations: A new clinical guideline

The European Respiratory Society and the American Thoracic Society have released a guideline for the treatment of patients with COPD exacerbations.

PCV10 vaccine decreases pneumonia rate in children

PCV10 decreases rate of pneumonia among vaccine-eligible children and older, unvaccinated children.

High cardiac troponin levels may predict mortality in community-acquired pneumonia

Elevated cardiac troponin T is also strongly prognostic of cardiac mortality observed in association with community-acquired pneumonia.

Antibiotic prescribing in primary care varies for community-acquired pneumonia

Factors that contribute to antibiotic choice for CAP include patient age, previous antibiotic receipt, and private insurance.

Pneumococcal conjugate vaccine reduces Streptococcus pneumoniae bacteremia

Researchers observed a 95.3% reduction of Streptococcus pneumoniae bacteremia after implementation of routine immunization with the pneumococcal conjugate vaccine.

Statins may reduce pulmonary artery pressure in COPD patients

A daily dose of atorvastatin could reduce pulmonary artery pressure among patients with COPD.

Early use of noninvasive techniques for clearing respiratory secretions in COPD

A novel technique involving NPPV reduced the risks of nosocomial infection, requirement for intubation, and hospital mortality in patients with COPD.

ICU may be overused for some patients with heart or lung disease

Researchers also observed no difference in 30-day mortality rates between patients in the ICU and those who received regular inpatient care in another hospital unit.

Global tobacco control treaty reduced worldwide smoking rates

Countries committed to introducing policies such as high tobacco taxes and smoke-free public spaces.

Low vitamin E in pregnant women increases asthma risk in offspring

Research presented at the AAAAI Annual Meeting suggests a link between maternal vitamin E levels and childhood asthma development.

Ultrasound vs radiology for diagnosing pneumonia

Point of care lung ultrasound is an accurate tool for the diagnosis of pneumonia, according to researchers.

Cystic fibrosis: consensus diagnostic guidelines for clinicians

The guidelines outline the diagnosis of CF and clarify diagnostic criteria and terminology for other disorders associated with CFTR mutations.

Inhaled corticosteroids not tied to pneumonia in children with asthma

Results showed no link between inhaled corticosteroids and risk of pharyngitis, otitis media, or sinusitis.

Fruit and vegetable consumption reduces risk of COPD in smokers

A strong inverse association between total fruit and vegetable consumption and COPD was observed in smokers but not in never-smokers.

Vitamin D supplementation reduces the risk of acute respiratory tract infection

Patients receiving vitamin D for deficiency without bolus doses experienced the most benefit.

More antimicrobial treatments needed in community-acquired pneumonia

Findings from a US claims-based retrospective study call for more effective antimicrobial treatments for patients with community-acquired pneumonia.

2017 Adult immunization schedule released by the CDC

The ACIP has released the 2017 recommended immunization schedule for adults.

2017 immunization schedule for children and adolescents released by CDC

The schedule includes new or revised recommendations for several vaccines for children and adolescents.

Electronic cigarette use linked to higher CVD risk

Electronic cigarettes cause an imbalance of cardiac autonomic tone and increased oxidative stress, which may increase cardiovascular risk.

High-potency statins increase hospitalization for community-acquired pneumonia

Higher-potency statins increased hospitalization for community-acquired pneumonia compared with lower-potency statins.

Recurrent pneumonia resulting from misdiagnosed endobronchial suture—a case synopsis

Endobronchial suture should be considered in patients with recurrent pneumonia that is unresponsive to medical therapy.

Pneumococcal vaccination reduces pneumonia risk in COPD patients

Polyvalent pneumococcal vaccines offered protection against community-acquired pneumonia in COPD patients.

Pneumonia vaccine may not be effective in rheumatoid arthritis patients

The PPSV23 vaccine may not prevent pneumonia in patients with rheumatoid arthritis.

VA lung cancer screening program finds high rate of incidental findings, low cancer detection rate

An estimated 900,000 veterans of a population of 6.7 million VHA patients met the criteria for LCS.

One-third of asthma patients may be misdiagnosed

About one-third of adults with physician-diagnosed asthma in the last 5 years may not have a current diagnosis.

Monitoring asthma control in children: AAP recommendations for clinicians

Recent advances in measuring asthma control tools have enhanced ongoing assessment and monitoring of asthma.

COPD exacerbations reduced with budesonide/formoterol treatment

Budesonide/formoterol treatment decreased exacerbations in COPD after 3 months.

Patients with chronic diseases are frequently overly optimistic about life expectancy

Self-estimated life expectancy rates may differ from clinician-estimated rates of survival.

Morning symptoms in COPD linked to limited physical activity

Many patients with COPD report morning symptoms that are negatively associated with physical activity.

Medicare bundled payment initiative did not reduce COPD readmissions

The multidisciplinary care intervention did not reduce COPD readmissions or achieve substantial savings.

Prenatal fish oil supplementation may reduce asthma risk in children

Supplementation during pregnancy was associated with reduction in risk of persistent wheezing and asthma in offspring.

Higher cured meat intake linked to worsening asthma

Cured meat intake levels also had an indirect effect mediated by body mass index.

Exposure to mold and dampness may increase risk of asthma and rhinitis

Exposure during infancy was associated with increased risk up to 16 years of age, especially for nonallergic disease.

GOLD Report includes updated COPD management recommendations

The GOLD Report includes a revised definition of COPD and updates guidelines for managing exacerbations.

Proposing new concepts and definitions in COPD

It is important to use the right terminology when discussing medical terms, specifically ones associated with smoke-related respiratory conditions, according to the researchers.

Predicting COPD exacerbation onset with use of physiological parameters

Researchers conducted a systematic review of the effectiveness of monitoring physiological parameters to predict COPD exacerbations.

IV catheters vs oral antibiotic treatment for pediatric pneumonia

Children with complicated pneumonia should preferentially receive oral antibiotics at discharge when effective oral options are available

Smoking more harmful for HIV patients than the virus

Men and women who quit smoking after entering HIV care at age 40 years gained 5.7 years and 4.6 years of life expectancy, respectively, compared with those who continued to smoke.

Improvement needed in managing COPD in women

The prevalence of COPD globally is increasing more rapidly in women than in men.

COPD Assessment Test indicates mortality risk in interstitial lung disease

Researchers conducted a study to verify the CAT as a predictor of outcome among patients with interstitial lung disease.

Indoor environmental control strategies to manage asthma in children

Strategies include source removal, source control, and asthma education.

Questionnaire and peak expiratory flow identify undiagnosed COPD

The CAPTURE questionnaire with peak flow can identify patients who would benefit from COPD therapy.

Cancer-related deaths attributed to smoking vary across states

Cancer deaths attributed to cigarette smoking are common among the Southern states.

Long-term oxygen therapy not beneficial for COPD patients with moderate desaturation

Long-term supplemental oxygen has no benefit in patients with stable COPD and resting or exercise-induced moderate desaturation.

COPD and idiopathic pulmonary fibrosis may have common genetic network

Researchers used integrated genomics to identify convergent transcriptomic pathways in emphysema and IPF.

Omalizumab effective for asthma and overlapping COPD

Omalizumab is useful in the management of severe asthma with overlapping COPD.

Pulmonary embolism common in patients hospitalized for syncope

One in 6 patients hospitalized for a first episode of syncope experiences a pulmonary embolism.

Children with farm exposure have decreased regulatory T cells

Regulatory T cells are decreased with farm exposure and increased among those with asthma.

Number of COPD cases predicted to increase until 2030

Researchers predict that the number of COPD cases will increase by more than 150% from 2010 to 2030.

Endoscopic sinus surgery may improve asthma quality of life in rhinosinusitis

Endoscopic sinus surgery improved asthma quality of life and control in patients with uncontrolled asthma.

Allergic sensitization is common in pediatric asthma

Children were assessed for allergic sensitization by two microarray system. As a result, 47% of children had allergic sensitization.

Acute exacerbations may accelerate lung function decline in smokers with COPD

Exacerbations were associated with accelerated lung function loss in patients with established COPD.

Screening for latent tuberculosis infection: USPSTF finalizes recommendation

The USPSTF task force reviewed evidence regarding screening for LTBI in asymptomatic adults.

Sign Up for Free e-newsletters