Rheumatology News Archive

Anakinra May Be Effective for Treatment of Acute Gout Flares

Researchers evaluated the efficacy and safety of anakinra for the treatment of acute gout flares.

Working Group Endorses Patient-Reported Outcome Measure for PsA-Related Quality of Life

The Psoriatic Arthritis Impact of Disease questionnaire was endorsed as a core outcome measure for psoriatic arthritis-specific health-related quality of life.

Greater Walking Frequency, Duration May Reduce Risk for Low Back Pain

Regular and prolonged walking was found to be associated with a reduced the risk for low back pain in Koreans age >50.

Patients With Sleep Apnea Have Increased Gout Risk

Among OSA patients, risk for developing gout is highest 1 to 2 years after the index date.

Managing Bisphosphonate Drug Holidays in Patients With Osteoporosis

Ongoing treatment with bisphosphonate therapy may not be needed to prevent future fractures in certain patients due to the sustained effect of the drug.

Blunted Cardiovascular Stress Reactivity in Fibromyalgia With Comorbid PTSD

For women with fibromyalgia, comorbid posttraumatic stress disorder may contribute to blunted cardiovascular reactivity to stress.

Several Factors Tied to Early Readmission After Hip Fracture Surgery

Parkinson's, osteoarthritis, rheumatic disease, heavy alcoholism linked to increased risk for readmission.

Managing Psoriatic Arthritis: Updated 2018 Recommendations From ACR/NPF

The American College of Rheumatology and the National Psoriasis Foundation have released 2018 joint recommendations for the treatment of psoriatic arthritis.

Early PT Linked to Less Opioid Use in Musculoskeletal Pain

For opioid-naive patients, early physical therapy tied to less opioid use in shoulder, neck, knee, back pain.

BMI May Mediate Inverse Link Between Fiber Intake, Knee Osteoarthritis

But link between fiber intake and knee osteoarthritis was significant in only 1of 2 studies.

Smoking Linked to Cognitive Dysfunction in Fibromyalgia

In adjusted analysis, smoking tied to worse symptom severity, sleep problems, anxiety, depression.

Menopausal Hormone Therapy May Reduce Carpal Tunnel Syndrome Risk

To investigate the association between hormone therapy and carpal tunnel syndrome risk, researchers conducted a secondary analysis of the Women's Health Initiative (WHI) hormone therapy trials.

Subclinical Myocardial Inflammation Common in Rheumatoid Arthritis

Data show that myocardial inflammation in rheumatoid arthritis is related to disease activity and may contribute to increased risk for heart failure.

Examining the Role of Diet in Rheumatoid Arthritis

Many components of diet have been implicated as possible risk factors for RA, with varying degrees of evidence.

Joint Mobilization Plus Exercise Beneficial for Knee Osteoarthritis

At 24 weeks, improvements seen in pain, function for osteoarthritis patients who did patellar mobilization.

Parental Chronic Spinal Pain May Affect Prognosis in Adult Offspring

Individuals with chronic spinal pain, particularly those who are overweight or obese, may be less likely to recover from this condition if both their parents also have chronic spinal pain.

Case Study: White Paste Found After Ankle Aspiration

A 53-year-old obese man with a history of diabetes and hypertension presents with migratory bilateral ankle pain that is worse on the left side.

Workplace, Clinical Factors Linked to Employment Outcomes in Axial Spondyloarthritis

Data identified both clinical and employment factors that may predict poor work outcomes in patients with axial spondyloarthritis.

Examining Insurance Complications in the Shared Decision Making Process for Rheumatoid Arthritis

The addition of third-party insurance companies in the shared decision-making process complicated efficiency in terms of participants' decisions as well as timely treatment.

Bone Erosions More Frequent With Old Age at Onset of Early RA

Bone erosions more frequent in those older at early RA onset even if they had clinical remission.

Functional Disability Progression More Rapid in Postmenopausal Women With RA

Functional disability progressed more rapidly in postmenopausal compared with premenopausal women with rheumatoid arthritis.

CDC: About 1 in 3 Adults With Prediabetes Has Arthritis

About 1 in 3 adults with prediabetes has arthritis, and half of those with both conditions are physically inactive and/or obese.

Panel Issues Consensus Statement on Management of Gouty Arthritis of the Foot and Ankle

An expert panel evaluated 23 separate statements related to the etiology, diagnosis, and treatment of gout.

Failure to Meet Optimal Urate Levels Increases Mortality Risk in Gout

Patients with gout who did not reach a serum uric acid level below 6 mg/dL had a 2.4-fold increased risk for death.

ACR/ARHP 2018: Researchers Debate Hydroxychloroquine Dosing in SLE

Experts at the 2018 ACR/ARHP Annual Meeting discuss whether hydroxychloroquine dosing should be more than 5 mg/kg in patients with systemic lupus erythematosus.

Gout Outcomes Favorable With Nurse-Led Care

In a British study, nurse-led care emphasizing patient education and engagement significantly improved the proportion of gout sufferers who achieved target serum urate levels.

High Burden of Depression, Anxiety Reported Among Adults With Arthritis

Data from the CDC show that the prevalence of anxiety and depression is higher among adults with arthritis compared with the general population.

Gabapentin Superior to Pregabalin for Chronic Sciatica

For patients with chronic sciatica, gabapentin is superior to pregabalin, with fewer and less severe adverse events.

Expanding Healthcare Access With Nurse-Led Care in Rheumatoid Arthritis

A recent systematic review found that nurse-led care is effective, acceptable, and safe in patients with rheumatoid arthritis.

Allopurinol Dose Escalation for Gout Does Not Improve Mortality

Linked to small increase in mortality; at 2 years, 31% of dose escalators achieved serum urate goal.

Many RA Patients' Pain Related to Central Nervous System

MRIs show rheumatoid arthritis patients have neurobiologic features observed in fibromyalgia.

Effects of Pain, Depression, and Insomnia on Health Care Use in Older Adults With Osteoarthritis

The combined effects of pain with insomnia and pain with depression increased diverse types of health care use.

Mediterranean Diet Tied to Lower Risk of Rheumatoid Arthritis

Association only significant among men and only in seropositive rheumatoid arthritis.

Internet-Delivered Exposure Therapy Cost-Effective for Patients With Fibromyalgia

In a randomized control trial, researchers found that internet-delivered exposure therapy was more cost-effective for patients with fibromyalgia than a waitlist control, which did not involve any treatment during the experimental phase of the study.

Fifteen Genetic Determinants of Fracture Identified

All determinants also associated with bone mineral density, which showed causal effect on fracture.

EULAR Releases 2018 Recommendations for the Management of Hand Osteoarthritis

EULAR has released updated guidelines for the management of hand osteoarthritis.

Mobile Apps for Rheumatoid Arthritis Require More Comprehensive User Experiences

Most mobile apps directed toward individuals with rheumatoid arthritis do not provide a comprehensive experience.

Graded In Vivo Exposure Elements May Benefit Chronic Lower Back Pain Management

Integrating graded in vivo exposure into the management of chronic lower back pain may result in improved treatment efficacy and reduced pain-related fear.

Spinal Manipulation Plus Exercise Effective for Teen Low Back Pain

Spinal manipulative therapy plus exercise more effective than exercise alone over 1-year period.

Chronic Low Back Pain Levels Vary Between Sex and Race

Differences exist in race and gender in patients with chronic lower back pain, especially in pain sensitivity and severity due to aftersensations from mechanical punctuate pain and deep muscle hyperalgesia.

Elevated Late Mortality Persists After Blood or Marrow Transplant

But in past 3 decades, decrease in late mortality seen among those who underwent BMT in childhood.

Antirheumatic Medication Management for Orthopedic Surgery: An Interdisciplinary Perspective

A rheumatologist and orthopedic surgeon provide an interdisciplinary perspective on the perioperative management of antirheumatic medications in patients undergoing elective orthopedic surgery.

Combination Therapies for Low Back Pain, Sciatica May Not Have Added Benefit

There is a lack of evidence supporting the benefits of combination drug therapy over monotherapy for the management of low back pain and sciatica.

EULAR Releases 2018 Guideline on Physical Activity in Inflammatory Arthritis, Osteoarthritis

The European League Against Rheumatism has issued their 2018 recommendations for physical activity in patients with inflammatory arthritis and osteoarthritis.

Effect of Mediterranean Diet Plus Vitamin D3 on Bone Density in Osteoporosis

Investigators examined the effect of consuming a Mediterranean-style diet for 1 year on inflammatory response and bone health in the elderly.

Radiofrequency Denervation Efficacious in Treating Thoracic Zygapophyseal Joint Pain

Radiofrequency denervation, typically used to treat lumbar and cervical zygapophyseal joint pain, has shown efficacy in treating thoracic zygapophyseal joint pain.

Acute Coronary Syndrome Risk Elevated in Siblings of Patients With RA

Siblings of patients with rheumatoid arthritis appear to have an increased risk for acute coronary syndrome, which suggests there is a shared susceptibility between the 2 conditions.

NKTR-181 for Chronic Lower Back Pain: SUMMIT-07 Results

The phase 3 SUMMIT-07 trial assessed the safety, efficacy, and tolerability of a new mu-opioid receptor agonist analgesic in adults with moderate to severe chronic lower back pain.

Osteoporosis Fracture Risk Awareness Lacking in Postmenopausal Women

Postmenopausal women have little awareness of osteoporotic fracture risk and poor understanding that a fragility fracture may be indicative of osteoporosis and that it increases future fracture risk.

NSAID Use May Increase CVD Risk in Osteoarthritis

Nonsteroidal anti-inflammatory drug use mediated a substantial amount of cardiovascular disease risk in osteoarthritis.

Restless Legs Syndrome, Fibromyalgia, and Depression Frequent in Migraine

Patients with migraine may exhibit higher prevalence of restless leg syndrome, fibromyalgia, and depressive symptoms compared with individuals not experiencing migraines.

Moderate Alcohol Consumption Linked to Increased Disease Progression for Women With RA

Moderate consumption of alcohol is associated with increased radiological progression in women with early RA.

Corticosteroid Plus Lidocaine Injections Do Not Alleviate Pain in Central Lumbar Spinal Stenosis

Adding corticosteroids to epidural lidocaine injections does not improve patient-reported pain or function at 12 months.

Incident Gout Risk, Serum Urate, and Comorbidities: What Are the Links?

Ethnicity and hypertension have an association with incident gout that is not fully explained by differences in serum urate.

Adding Chiropractic to Usual Care Beneficial for Low Back Pain

Improvements in low back pain intensity and disability among active-duty military personnel

Hand Grip Strength Associated With All-Cause Mortality, Other Adverse Outcomes

Grip strength is strongly and inversely associated with all-cause mortality and incidence of and mortality from cardiovascular disease, respiratory disease, COPD, all cancer, and subtypes of cancer, with associations being modestly stronger in the younger age groups.

Rheumatology Curriculum Outline Aims to Train and Integrate NPs and PAs

The ACR/ ARHP created a rheumatology curriculum outline that can be used to create more efficient integration of NPs and PAs into rheumatology practice.

Case Report: Nephrotic Syndrome and Chronic HCV in a 72-Year-Old Woman

A 72-year-old Japanese woman with a 40-year history of lupus nephritis presented with leg edema that had lasted for several weeks.

Addition of Peripheral Nerve Blocks Beneficial for TKA

Lower numeric rating scale pain scores on ambulation on postoperative days zero, one, and two

Tai Chi May Be Therapeutic Option for Fibromyalgia

Tai chi interventions may be more effective at treating fibromyalgia than aerobic exercise.

Pain sensation may be altered by verum, sham electroacupuncture

Functional magnetic resonance imaging was used to monitor brain activity in patients with osteoarthritis who were administered either genuine or placebo electroacupuncture.

FDA warns that febuxostat may increase risk of heart-related mortality

Preliminary clinical trial results show more heart-related deaths occur in patients taking febuxostat compared to allopurinol.

USPSTF recommends osteoporosis screening, testing in women aged 65 and older

The USPSTF has updated its recommendations on osteoporosis screening and testing in women and men.

Steroid treatment effective for carpal tunnel syndrome

The researchers found that four weeks after treatment there was significant improvement in Boston Carpal Tunnel Questionnaire scores.

Early antiretroviral therapy initiation linked to bone loss in HIV patients

Early antiretroviral therapy initiation may increase the rate of bone loss in HIV patients.

DASH diet associated with lower risk of gout

The DASH diet could offer a dietary strategy that may help prevent gout and its comorbidities in high-risk patients with hyperuricemia.

Osteoporotic fracture risk linked to mental disorders and related medication use

Researchers used FRAX scores to examine the association of mental disorders and related medication use with osteoporotic fracture risk in clinical practice.

PAs may help fill rheumatology workforce shortage

The gap between supply and demand in the rheumatology workforce is expected to widen substantially by 2030.

FDA approves radiofrequency treatment for osteoarthritis knee pain

The FDA has cleared Halyard Health's COOLIEF Radiofrequency Treatment for relief of chronic osteoarthritis knee pain.

Stroke risk increases after herpes zoster in patients with autoimmune disease

Herpes zoster was linked to an increased stroke risk in first 90 days among patients with an autoimmune disease.

NSAIDs have little effect for spinal pain

The researchers estimated that only 1 in 6 patients gained a benefit from taking NSAIDs.

Raynaud phenomenon: a cold-weather condition

A thorough work-up can differentiate between primary and secondary forms, mitigating progression of a more severe underlying disease.

Alternative strategies effective for diagnosing gout

Multidimensional algorithms may help clinicians make a provisional diagnosis of gout.

Functional outcomes in septic arthritis after ultrasonography

Patients with septic arthritis with poor functional outcome who underwent ultrasonography showed decreased synovial thickness at 3 months.

Benefits of structured rehabilitation program for hand osteoarthritis

Patients benefit from non-pharmacological treatment in a structured arthritis rehabilitation program.

Consultation rates for symptoms related to inflammatory arthritis increase prior to diagnosis

Consultations for musculoskeletal symptoms and infections increase prior to an inflammatory arthritis diagnosis.

Platelet-rich plasma SIJ injection cuts low back pain

The researchers found that patients who received the injection had significantly lower intensity of pain at six weeks and at three months compared with patients who didn't.

Multibiomarker disease activity predicts relapse in rheumatoid arthritis patients

Multibiomarker disease activity improved relapse prediction in RA patients who are in remission.

Patient personality may affect treatment adherence in rheumatoid arthritis

Early and aggressive management of RA is urged by investigators.

Age as a determining factor in TNFi discontinuation in rheumatoid arthritis

It is critical to identify disease-modifying antirheumatic drugs for elderly patients with rheumatoid arthritis.

Ultrasonography used to guide drug modification in arthritis

Researchers found that ultrasonography of selected joints can improve clinical assessment.

IV lidocaine plus amitriptyline has no impact in fibromyalgia

No difference was recorded between patients treated with lidocaine plus amitriptyline versus patients treated with acetaminophen and tramadol.

For chronic low back pain, opioids only moderately effective

For patients with chronic low back pain, opioids may provide some short-term relief but are unlikely to be effective within recommended doses.

Cannabinoids may provide moderate benefit for rheumatic conditions

Researchers found no serious adverse events related to treatment with cannabinoids.

Oral glucocorticoid use increases risk of diabetes in patients with rheumatoid arthritis

Glucocorticoid therapy in patients with rheumatoid arthritis has been linked to elevated risk of diabetes.

Probiotics improve clinical, metabolic status in rheumatoid arthritis

After 8 weeks, patients with rheumatoid arthritis who took probiotics showed improvements in disease activity and metabolic health.

Pain complexities in rheumatoid arthritis

Nearly 12% of patients in remission from RA still experience clinically significant pain.

High fatigue common in psoriatic arthritis

Nearly 50% of patients with psoriatic arthritis report elevated levels of fatigue.

Overweight, obese patients have increased osteoarthritis risk

The risk of developing hand, hip, and knee osteoarthritis is increased in people who are overweight or obese.

FDA approves Inflectra biosimilar for rheumatoid arthritis, psoriasis

The biosimilar has also been approved for Crohn's disease, ulcerative colitis, and ankylosing spondylitis.

In rheumatoid arthritis, radiologic measures underrate ulnar deviation

In patients with rheumatoid arthritis, there are disparities between radiologic and goniometric measurements of joint deviation.

Mindfulness, CBT can reduce chronic low back pain

Mindfulness-based stress reduction and cognitive behavior therapy may be useful to improve chronic low back pain.

Green tea compound shows potential for rheumatoid arthritis

A molecule found in green tea may block a protein that causes the symptoms of rheumatoid arthritis.

A multidisciplinary approach to treating enteropathic spondyloarthritis

A multidisciplinary approach to diagnosing and treating enteropathic spondyloarthritis (ESpA) is the best way to ensure a patient gets comprehensive care.

Biologic treatment for RA leads to low disease activity, clinical remission

RA patients treated with biologics have exhibited either clinical remission or low disease activity on follow-up visits.

Cardiovascular deaths reduced among patients with RA

Cardiovascular deaths have significantly decreased among people with rheumatoid arthritis.

Decrease in mortality for patients with rheumatoid arthritis

Due to improved treatment options, rheumatoid arthritis mortality rates have decreased since 2000.

DMARDs remain first choice of therapy for rheumatoid arthritis

Updated American College of Rheumatology recommendations suggest using first-line DMARDs in combination with biologic agents and nonbiologic DMARDs to achieve therapeutic efficacy in rheumatoid arthritis treatment.

Rheumatoid arthritis disease activity improvement with bariatric surgery

Research has shown a positive correlation between bariatric surgery-associated weight loss and decreased rheumatoid arthritis disease activity.

Patients with RA display lower disease activity at NP, PA-staffed practices

Patients with rheumatoid arthritis who are treated at practices with NPs and PAs exhibited lower disease activity over 2 years.

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